Raquel Espinosa-Romero
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View article: 68P Prognosis of ovarian cancer patients with the Mexican founder mutation (a BRCA1 long genomic rearrangement) compared with other BRCA1/2 mutations
68P Prognosis of ovarian cancer patients with the Mexican founder mutation (a BRCA1 long genomic rearrangement) compared with other BRCA1/2 mutations Open
Mexican women with ovarian cancer have a high prevalence of germline BRCA mutations. The most frequent alteration is the deletion of exons 9 to 12 of BRCA1 (BRCA1-Del Exon 9-12), which has been associated with a founder effect in this popu…
View article: Clinical Benefits of Olaparib in Mexican Ovarian Cancer Patients With Founder Mutation BRCA1-Del ex9-12
Clinical Benefits of Olaparib in Mexican Ovarian Cancer Patients With Founder Mutation BRCA1-Del ex9-12 Open
Background: Ovarian cancer (OC) is gynecologic cancer with the highest mortality rate. It is estimated that 13–17% of ovarian cancers are due to heritable mutations in BRCA1 and BRCA2 . The BRCA1 ( BRCA1 -Del ex9-12) Mexican founder mutati…
View article: Standard Treatment with Bevacizumab as Targeted Therapy in Cervical Cancer
Standard Treatment with Bevacizumab as Targeted Therapy in Cervical Cancer Open
View article: Experience with the use of olaparib in patients with ovarian cancer
Experience with the use of olaparib in patients with ovarian cancer Open
Introducción: Más del 20 % de los cánceres de ovario puede ser hereditario y la mayoría tiene mutaciones BRCA.El 33 % de las pacientes mexicanas con mutación BRCA1 tiene la mutación fundadora, la cual es una deleción de los exones 9 al 12 …
View article: High prevalence of human papillomavirus and European variants of HPV 16 infecting concomitantly to cervix and oral cavity in HIV positive women
High prevalence of human papillomavirus and European variants of HPV 16 infecting concomitantly to cervix and oral cavity in HIV positive women Open
The high prevalence of HPV, multiple infections and presence of the EP350G intravariant in both anatomical regions are strongly related to the persistence of the virus, which is fundamental for the development of cancer. Therefore, it is v…
View article: Clinical Evaluation of BRCA1/2 Mutation in Mexican Ovarian Cancer Patients
Clinical Evaluation of BRCA1/2 Mutation in Mexican Ovarian Cancer Patients Open
View article: Experiencia con el uso de olaparib en pacientes con cáncer de ovario
Experiencia con el uso de olaparib en pacientes con cáncer de ovario Open
Olaparib offers greater PFS benefit as maintenance therapy after a first and second relapse. Patients with founder mutation have had sustained PFS.
View article: Cuarto Consenso Nacional de Cáncer de Ovario
Cuarto Consenso Nacional de Cáncer de Ovario Open
View article: Epidemiological overview, advances in diagnosis, prevention, treatment and management of epithelial ovarian cancer in Mexico
Epidemiological overview, advances in diagnosis, prevention, treatment and management of epithelial ovarian cancer in Mexico Open
The epithelial ovarian cancer (EOC) has been underdiagnosed because it does not have a specific clinical presentation, and the signs and symptoms are similar to the irritable bowel syndrome and pelvic inflammatory disease. EOC is less comm…