Rashmi Rasalkar
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View article: Low Pass Whole Genome sequencing - a cost-effective new technique for the identification of aneuploidies and copy number variations: a study of 1372 clinical samples in an Indian cohort
Low Pass Whole Genome sequencing - a cost-effective new technique for the identification of aneuploidies and copy number variations: a study of 1372 clinical samples in an Indian cohort Open
Background Identification and confirmation of copy number variation is an important aspect of genetic testing for several prenatal scenarios, such as abnormal maternal serum screening, abnormal ultrasound findings, high risk results on non…
View article: Mosaic embryo transfer after pre-implantation genetic testing for structural rearrangement: a case study
Mosaic embryo transfer after pre-implantation genetic testing for structural rearrangement: a case study Open
Background: Identifying the cause of recurrent pregnancy loss (RPL) helps in the direct management of future pregnancies. In 3%-4% of cases, a chromosomal structural rearrangement is identified in the couple. Pre-implantation genetic testi…
View article: MiRNA-146a Polymorphism Was Not Associated with Malaria in Southern India
MiRNA-146a Polymorphism Was Not Associated with Malaria in Southern India Open
Micro-RNAs (miRNAs) play a crucial role in immune regulation, and a common miRNA-146a polymorphism (rs2910164) increased the odds of falciparum malaria in pregnant African women. Here, we examined whether this association holds true in a d…
View article: Duffy antigen receptor for chemokines gene polymorphisms and malaria in Mangaluru, India
Duffy antigen receptor for chemokines gene polymorphisms and malaria in Mangaluru, India Open
Background Duffy blood group antigens serve as receptors for Plasmodium vivax invasion into erythrocytes, and they are determined by polymorphisms of the Duffy antigen receptor for chemokines (DARC), also known as Fy glycoprotein (FY). Duf…
View article: Characterization of Plasmodium vivax pvmdr1 Polymorphisms in Isolates from Mangaluru, India
Characterization of Plasmodium vivax pvmdr1 Polymorphisms in Isolates from Mangaluru, India Open
India accounts for approximately half of the global Plasmodium vivax cases, but information as to the presence of chloroquine (CQ) resistance is scarce. In an observational study in Mangaluru, south-western India, of 116 vivax malaria pati…
View article: Molecular Evidence for Plasmodium falciparum Resistance to Sulfadoxine–Pyrimethamine but Absence of K13 Mutations in Mangaluru, Southwestern India
Molecular Evidence for Plasmodium falciparum Resistance to Sulfadoxine–Pyrimethamine but Absence of K13 Mutations in Mangaluru, Southwestern India Open
In most of India, sulfadoxine–pyrimethamine (SP) plus artesunate serves as first-line treatment for uncomplicated falciparum malaria. In 112 clinical Plasmodium falciparum isolates from Mangaluru, southwestern India, we sequenced molecular…
View article: Manifestation of malaria in Mangaluru, southern India
Manifestation of malaria in Mangaluru, southern India Open