Rasna Gupta
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View article: Clinical Significance of Tumor Grade in Triple-Negative Breast Cancer: A Retrospective Cohort Analysis
Clinical Significance of Tumor Grade in Triple-Negative Breast Cancer: A Retrospective Cohort Analysis Open
Triple-negative breast cancer (TNBC) is a heterogeneous cancer that lacks estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptor 2 (HER2) proteins. Here, we investigated the prognostic value of gra…
View article: Real-World Experience with CDK4/6 Inhibitors in the First-Line Palliative Setting for HR+/HER2− Advanced Breast Cancer
Real-World Experience with CDK4/6 Inhibitors in the First-Line Palliative Setting for HR+/HER2− Advanced Breast Cancer Open
Introduction: CDK4/6 inhibitors in combination with aromatase inhibitors (AIs) are the standard first-line treatment for hormone receptor-positive (HR+), HER2-negative (HER2−) metastatic breast cancer. Landmark trials have demonstrated a c…
View article: Real-World Experience with CDK4/6 Inhibitors in the First-Line Palliative Setting for HR+/HER2- Advanced Breast Cancer
Real-World Experience with CDK4/6 Inhibitors in the First-Line Palliative Setting for HR+/HER2- Advanced Breast Cancer Open
Introduction: CDK4/6 inhibitors in combination with aromatase inhibitors (AI) are the standard first-line treatment for hormone receptor-positive (HR+), HER2-negative (HER2-) metastatic breast cancer. Landmark trials have demonstrated comp…
View article: Presentation and Outcome of Patients with Multiple Myeloma (MM), Single Centre Experience from Windsor Essex Regional Cancer Centre
Presentation and Outcome of Patients with Multiple Myeloma (MM), Single Centre Experience from Windsor Essex Regional Cancer Centre Open
Our study showed comparable outcome for patients with multiple myeloma despite older age and higher risk disease. Outcome is expected to improve with the introduction of more novel agents.
View article: A Retrospective Single Center Study Investigating the Clinical Significance of Grade in Triple Negative Breast Cancer
A Retrospective Single Center Study Investigating the Clinical Significance of Grade in Triple Negative Breast Cancer Open
management is primarily chemotherapy and surgical resection of localized tumors [9,10], followed by radiotherapy.Despite advances in novel immunotherapies and the discovery of additional biomarkers serving as therapeutic targets, TNBC rema…
View article: Prevalence of Chronic Kidney Disease and its Association with Risk Factors in Eastern Uttar Pradesh, India
Prevalence of Chronic Kidney Disease and its Association with Risk Factors in Eastern Uttar Pradesh, India Open
Background: Chronic kidney disease (CKD) is a global health problem with high mortality and morbidity rates. CKD is found associated with a number of life threatening diseases such as diabetes, anemia, liver and cardiovascular diseases. CK…
View article: Survival of patients with pancreatic cancer treated with varied modalities: A single-centre study
Survival of patients with pancreatic cancer treated with varied modalities: A single-centre study Open
The present retrospective chart review examined the overall survival (OS) of patients with pancreatic ductal adenocarcinoma based on the disease stage in a sample of 296 patients with pancreatic cancer. Secondary outcome measurements inclu…
View article: Early Stage Triple Negative Breast Cancer Has Significantly Better Outcomes than More Advanced Disease: A Single Centre Retrospective Review
Early Stage Triple Negative Breast Cancer Has Significantly Better Outcomes than More Advanced Disease: A Single Centre Retrospective Review Open
A retrospective, serial analysis of 181 triple negative breast cancer (TNBC) patients was undertaken at a regional cancer centre in Canada. The primary focus of the analysis was to investigate the effect of presenting stage in patients wit…
View article: Real world experience with dose dense ac-paclitaxel: Two canadian cancer centers’ experience
Real world experience with dose dense ac-paclitaxel: Two canadian cancer centers’ experience Open
Early breast cancer treatment with dose dense Adriamycin-Cyclophosphamide and Paclitaxel (AC-P) has been shown to increase survival. However, it is commonly associated with neutropenia, anemia or both. This retrospective chart review study…