Raul Mihailov
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View article: Laparoscopic Management of Boerhaave Syndrome: Case Series and Narrative Review
Laparoscopic Management of Boerhaave Syndrome: Case Series and Narrative Review Open
Boerhaave syndrome, or spontaneous rupture of the esophageal wall, is a rare condition that occurs after a violent increase in intraesophageal pressure associated with negative intrathoracic pressure after forceful vomiting or retching. Ru…
View article: The deadly triple M (mistrust, misinformation, and missed opportunities): understanding Romania’s COVID-19 vaccination campaign and its lasting impact on public health
The deadly triple M (mistrust, misinformation, and missed opportunities): understanding Romania’s COVID-19 vaccination campaign and its lasting impact on public health Open
Romania’s COVID-19 vaccination campaign presents a compelling case study on the intersection of public health policy, societal dynamics, and political influences in pandemic response. Despite an initially promising rollout, Romania ultimat…
View article: The Potential of Artificial Intelligence in the Diagnosis and Prognosis of Sepsis: A Narrative Review
The Potential of Artificial Intelligence in the Diagnosis and Prognosis of Sepsis: A Narrative Review Open
Background/Objectives: Sepsis is a severe medical condition characterized by a dysregulated host response to infection, with potentially fatal outcomes, requiring early diagnosis and rapid intervention. The limitations of traditional sepsi…
View article: Literature Review of Prognostic Factors in Secondary Generalized Peritonitis
Literature Review of Prognostic Factors in Secondary Generalized Peritonitis Open
Generalized secondary peritonitis is a life-threatening intra-abdominal infection requiring urgent surgical intervention. Despite advances in surgical and antimicrobial therapy, morbidity and mortality remain high. Identifying key prognost…
View article: BCAA catabolism targeted therapy for heart failure with preserved ejection fraction
BCAA catabolism targeted therapy for heart failure with preserved ejection fraction Open
Rationale: Heart failure with preserved ejection fraction (HFpEF) is a major unmet medical need with limited effective treatments. A significant contributing factor to HFpEF, a multifactorial disease, is underlying metabolic dysfunc…
View article: The impact of Low-Anterior Resection Syndrome (LARS) on the Quality of Life in Rectal Cancer Survivors: a Narrative Review
The impact of Low-Anterior Resection Syndrome (LARS) on the Quality of Life in Rectal Cancer Survivors: a Narrative Review Open
Low anterior rectal cancer is based on oncological radicality and recurrence rates, which translate to survival. Rectal dysfunction occurred in at least one-quarter of patients. This dysfunction is a myriad of symptoms referred to as low a…
View article: Prognostic Factors of Postoperative Mortality in Patients with Complicated Right Colon Cancer
Prognostic Factors of Postoperative Mortality in Patients with Complicated Right Colon Cancer Open
The incidence of right colon cancer presenting in a stage with complications is significant. There are major differences in therapeutic approach between elective colon cancer surgery and emergency surgery. Complications such as hemorrhage,…
View article: Clinical and therapeutic aspects in skin cancer: Clinical study in a tertiary center from Romania
Clinical and therapeutic aspects in skin cancer: Clinical study in a tertiary center from Romania Open
Introduction: Skin cancer registers worldwide high morbidity and mortality rates, with costly medical services, its major histopathology subtypes being basal and squamous cell carcinoma, melanoma. Materials and method: This 5…
View article: Diagnostic and therapeutic particularities of a case admitted for low back pain and sciatica
Diagnostic and therapeutic particularities of a case admitted for low back pain and sciatica Open
Foreign bodies inserted urethral represent urological emergencies. Self-insertion of foreign bodies is a common practice, especially during states of pathological masturbation. Recently, presentations in emergency rooms with this type of p…
View article: Risk Factors for the Occurrence of Depressive Disorders in Pediatric Patients With Tuberculosis
Risk Factors for the Occurrence of Depressive Disorders in Pediatric Patients With Tuberculosis Open
Specific risk factors and vulnerabilities contribute to the development of depressive disorders in pediatric TB patients. Early identification and monitoring of these factors in a prospective framework are essential for improving the progn…
View article: Particular Aspects of Cardiac Rhythm Disorders in Pediatric Patients
Particular Aspects of Cardiac Rhythm Disorders in Pediatric Patients Open
Background: Cardiac rhythm disorders in children and adolescents have a high incidence. In certain conditions, sudden death may occur. Materials and Methods: We conducted a prospective study including 199 patients divided into two subgroup…
View article: Prognostic Factors of Postoperative Mortality in Patients with Complicated Right Colon Cancer
Prognostic Factors of Postoperative Mortality in Patients with Complicated Right Colon Cancer Open
The incidence of right colon cancer presented in the stage of complications is significant. There are major differences in therapeutic approach between elective colon cancer surgery and emergency surgery. Complications such as hemorrhage, …
View article: Prognostic Factors in Secondary Generalised Peritonitis
Prognostic Factors in Secondary Generalised Peritonitis Open
Introduction: Acute secondary peritonitis is a common clinical condition encountered in emergency hospital units, affecting a wide range of patients. The mortality rate for these patients is high and increases with the onset of sepsis, whi…
View article: Clinical Strategies for Identifying Pediatric Patients with Tuberculosis at Risk of Developing Depressive Disorders
Clinical Strategies for Identifying Pediatric Patients with Tuberculosis at Risk of Developing Depressive Disorders Open
Background: Tuberculosis remains a major global public health problem, affecting millions of people every year, including children. At the same time, depressive disorders are among the most common mental disorders in children and adolescen…
View article: The Management of Wound Healing in Infections after Hip Arthoplasty Using Stimulan and Negative Pressure Wound Therapy
The Management of Wound Healing in Infections after Hip Arthoplasty Using Stimulan and Negative Pressure Wound Therapy Open
Background: medical teams continue to face challenges with infections following hip replacement surgery, whether they occur shortly after the procedure or months or years later. Certain medical conditions like diabetes, rheumatoid arthriti…
View article: Serum Adiponectin Levels Increase in Acute Ischemic Stroke and Correlate with Patients’ Outcomes: A Pilot Study
Serum Adiponectin Levels Increase in Acute Ischemic Stroke and Correlate with Patients’ Outcomes: A Pilot Study Open
Stroke is a leading cause of death and severe disability worldwide. Rapid diagnosis is critical to ensure the timely administration of medical treatment. Given that in some cases CT scans fail to show the classic clinical signs of stroke, …
View article: The pathological and immunohistochemical profile of tumor angiogenesis in perforated sigmoid carcinoma–Case report and short literature review
The pathological and immunohistochemical profile of tumor angiogenesis in perforated sigmoid carcinoma–Case report and short literature review Open
Background: Little is known about the physiopathological factors or mechanisms that underlie tumor invasion of the serosa and lead to perforation in the peritoneal cavity. The aim of the work was to analyze the pathological and immu…
View article: The Efficacy of Antibiotic-Loaded Calcium Sulfate Beads (Stimulan) in Patients with Hip Arthroplasty Infections
The Efficacy of Antibiotic-Loaded Calcium Sulfate Beads (Stimulan) in Patients with Hip Arthroplasty Infections Open
Background: Given the increasing rate of infections following hip arthroplasty, one of the current options is the application of a biocomposite at the site of the infection. One of the products used is Stimulan, a completely resorbable cal…
View article: New Horizons of Artificial Intelligence in Medicine and Surgery
New Horizons of Artificial Intelligence in Medicine and Surgery Open
Background: Ideas about Artificial intelligence appeared about half a century ago, but only now is it becoming an essential element of everyday life. The data provided are becoming a bigger pool and we need artificial intelligence that wil…
View article: Giant Intraabdominal Lymphangioma in a Pediatric Patient—A Challenging Diagnosis
Giant Intraabdominal Lymphangioma in a Pediatric Patient—A Challenging Diagnosis Open
Introduction: Intra-abdominal cystic formations represent heterogeneous pathologies with varied localization and clinical manifestation. The first challenge of a giant intra-abdominal cystic lesion is identifying the organ of origin. The c…
View article: Giant Intraabdominal Lymphangioma in a Pediatric Patient
Giant Intraabdominal Lymphangioma in a Pediatric Patient Open
Introduction. Intra-abdominal cystic formations represent heterogeneous pathologies with varied localization and clinical manifestation. The first challenge of a giant intra-abdominal cystic lesion is identifying the organ of origin. The c…
View article: New Horizons of Artificial Intelligence in Medicine and Surgery
New Horizons of Artificial Intelligence in Medicine and Surgery Open
Ideas about Artificial Intelligence appeared about half a century ago, but only now is it becoming an essential element of everyday life. The data provided is getting bigger and bigger and, in this case, we need artificial intelligence tha…
View article: Surgical Emergencies in Patients with Hemophilia A—What to Expect
Surgical Emergencies in Patients with Hemophilia A—What to Expect Open
Surgical emergencies in patients with hemophilia A represent a major risk of mortality without proper multidisciplinary management and require prompt and effective treatment to prevent complications and improve patient outcomes. We present…
View article: Innovative Surgical Approaches That Improve Individual Outcomes in Advanced Breast Cancer
Innovative Surgical Approaches That Improve Individual Outcomes in Advanced Breast Cancer Open
Breast cancer is the most common cause of cancer death in women and the second cause in the general population. The incidence has increased over time. Women in developing countries often present at an advanced stage where initial surgery i…
View article: Ruptured Recurrent Interstitial Ectopic Pregnancy Successfully Managed by Laparoscopy
Ruptured Recurrent Interstitial Ectopic Pregnancy Successfully Managed by Laparoscopy Open
Ectopic pregnancies are a frequently encountered cause of first-trimester metrorrhagia. They occur when an embryo is implanted and grows outside the normal uterine space. Uncommonly, the embryo can be implanted in the intramural portion of…
View article: Unusual Localization of AIDS-Related Kaposi’s Sarcoma in a Heterosexual Male during the COVID-19 Pandemic: A Case Report
Unusual Localization of AIDS-Related Kaposi’s Sarcoma in a Heterosexual Male during the COVID-19 Pandemic: A Case Report Open
Kaposi’s sarcoma is an AIDS-defining illness and remains the most frequent tumor arising in HIV-infected patients with multifactorial etiology. We present a case of a 30-year-old Caucasian male with an 18-year history of HIV infection. The…
View article: Dental Anxiety- a Prospective Study among Medical and Non-Medical Subjects
Dental Anxiety- a Prospective Study among Medical and Non-Medical Subjects Open
The subject of anxiety related to dental treatments is recognized and long debated in medical literature. There are various motivations, starting with individual, age-related, social, economic or strictly medical reasons. Considering the m…
View article: The Importance of Involving a Multidisciplinary Team in the Management of a Patient Diagnosed with TB, Associating Erythema Nodosum
The Importance of Involving a Multidisciplinary Team in the Management of a Patient Diagnosed with TB, Associating Erythema Nodosum Open
Tuberculosis (TB) is an important and topical problem at global level, so it remains a challenge for public health policies . According to the World Health Organization (WHO), in 2018, about 10 million new TB cases worldwide were estimated…
View article: Unraveling the Mechanisms of Intestinal Insufficiency in Acute Peritonitis: A Comprehensive Overview
Unraveling the Mechanisms of Intestinal Insufficiency in Acute Peritonitis: A Comprehensive Overview Open
Acute peritonitis is a severe complication of abdominal surgery with a high mortality rate. Intes-tinal insufficiency syndrome (IIS) is a key factor in the progression of peritonitis, contributing significantly to morbidity and mortality. …
View article: A narrative review of cutaneous manifestations and imaging landmarks of breast cancer
A narrative review of cutaneous manifestations and imaging landmarks of breast cancer Open
Breast cancer is the most prevalent form of malignancy among women worldwide. Breast cancer can emerge on the skin in two ways: directly, as skin metastases or a direct extension of the tumor; or indirectly, as a paraneoplastic disease. Br…