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Safety assessment of RhD-positive red cell transfusion in RhD-negative liver-transplant recipients Open
Background & objectives: The number of blood components required during a liver-transplant surgery is significant. It is challenging for blood transfusion services to provide the required RhD-negative red blood cells (RBCs) for recipients …
Prophylactic administration of oral calcium carbonate during plateletpheresis: A bicentric prospective study Open
Prophylactic oral calcium carbonate supplementation would help in to reduce the risk of citrate toxicity. Therefore, we suggest for prophylactic oral administration of 3000 mg elemental calcium carbonate in three divided doses to make PP p…
Severe drug-induced immune hemolysis due to ceftriaxone Open
Drug-induced immune hemolytic anemia (DIIHA) is a rare condition that results primarily due to drug-induced antibodies, either drug dependent or drug independent. For its diagnosis, specialized immunohematology laboratory is often required…
Patient blood management in a patient with multiple red cell antibodies (anti-C, anti-e, and anti-K) undergoing liver transplant in South India: A team approach Open
End-stage liver disease (ESLD) patients undergoing liver transplant (LT) surgery are often multiply alloimmunized and pose significant challenges to the transfusion services in terms of red cell cross-match incompatibility, unpredictable b…
Comparison of a column agglutination technology-based automated immunohematology analyzer and a semiautomated system in pretransfusion testing Open
Based on study results, Vision was approved for routine use in laboratory. It was found to be reliable with considerably shorter TAT and capable of handling high throughput of immunohematological tests.
Comparison of conventional immunochromatographic assay with new automated-Treponema pallidum hemagglutination assay for screening of syphilis in blood donors Open
Introduction: Serological tests for syphilis contributed greatly to the detection of Treponema pallidum infection in blood donors and especially in those who were missed during the medical selection. Although several different treponemal a…
Successful treatment of Sezary syndrome with extracorporeal photopheresis – The first attempt in India Open
Sezary syndrome (SS) is more aggressive leukemic variant of cutaneous T-cell lymphoma in which a significant number of circulating malignant (Sezary) cells are observed in peripheral blood. Although single-agent or combination chemotherapy…
Evaluation of new indigenous “point‑of‑care” ABO and Rh grouping device Open
BACKGROUND: Erycard 2.0 is a “point-of-care” device that is primarily being used for patient blood grouping before transfusion. MATERIALS AND METHODS: Erycard 2.0 was compared with conventional slide technology for accuracy and time taken …
Advantages of type and screen policy: Perspective from a developing country! Open
Use of 'TS with IS crossmatch' policy provides multiple advantages to all the stakeholders; blood banker, clinician, patient, and the hospital management.
Alloimmunization in autoimmune hemolytic anemia patient: The differential adsorption approach Open
Patients of β-thalassemia major are dependent on regular blood transfusions for their entire lifetime. Development of antibodies against red blood cell (RBC) antigen which may be alloantibody or autoantibody, several times as a result of f…
First Indian study to establish safety of immediate-spin crossmatch for red blood cell transfusion in antibody screen-negative recipients Open
In AS-negative patients, IS crossmatch is as safe as conventional AHG crossmatch and can, therefore, replace conventional AHG crossmatch protocol.
Evaluation of nonspecific treponemal test rapid plasma reagin in comparison with specific treponemal test immunochromatographic assay for screening healthy blood donors Open
Introduction: Serological tests for syphilis (STS) contributed greatly to the detection of Treponema pallidum infection in blood donors and especially in those who were not identified during the medical selection. Most of the blood centers…
Total leukocyte count-based predictor tool for calculating hematopoietic progenitor cell dose in bone-marrow harvest Open
Background: Hematopoietic progenitor cell transplantation is increasingly being used as the curative therapy in India for various clinical conditions. There are three main sources of hematopoietic progenitor cells; hematopoietic progenitor…
Comparison of two algorithms to confirm and discriminate samples initially reactive for nucleic acid amplification tests Open
The study data suggest that replicate testing strategy and Ultrio Plus reduce the number of "inconclusive results" seen with earlier commonly used algorithm. We recommend a replicate testing strategy in ID-NAT testing since it will increas…
Newly established stem cell transplant program: 100 days follow-up of patients and its comparison with published Indian literature Open
Background: Hematopoietic progenitor stem cell transplantation (HPSCT) is used as a standard treatment option to improve outcome in hematological and nonhematological disorders. It is important for new HPSCT program to look at its patient …