Rawan K. El-Himri
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View article: Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis
Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis Open
Immune checkpoint inhibitors (ICIs) target advanced malignancies with high efficacy but also predispose patients to immune-related adverse events like immune-mediated colitis (IMC). Given the association between gut bacteria with response …
View article: Bacteroides ovatus alleviates dysbiotic microbiota-induced intestinal graft-versus-host disease
Bacteroides ovatus alleviates dysbiotic microbiota-induced intestinal graft-versus-host disease Open
Acute gastrointestinal intestinal GVHD (aGI-GVHD) is a serious complication of allogeneic hematopoietic stem cell transplantation, and the intestinal microbiota is known to impact on its severity. However, an association between treatment …
View article: Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment Open
Not all patients with cancer and severe neutropenia develop fever, and the fecal microbiome may play a role. In a single-center study of patients undergoing hematopoietic cell transplant ( n = 119), the fecal microbiome was characterized a…
View article: Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease
Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease Open
View article: Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment Open
Not all cancer patients with severe neutropenia develop fever, and the fecal microbiome may play a role. In neutropenic hematopoietic cell transplant patients (n=119), 63 (53%) developed a subsequent fever and had increased fecal Akkermans…