Razina Rouf
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View article: Antipsychotic effect of Aegiceras corniculatum (L.) Blanco: Evidence from murine behavioral assays and computational studies
Antipsychotic effect of Aegiceras corniculatum (L.) Blanco: Evidence from murine behavioral assays and computational studies Open
Introduction: Antipsychotic therapy targets the mesolimbic dopaminergic hyperactivity observed in schizophrenia. Drugs such as olanzapine (Zyprexa) alleviate positive symptoms by suppressing this pathway, although they are often associated…
View article: Assessment of antiemetic and modulatory activity of dihydrocoumarin on copper sulfate induced emetic chicks: An in vivo investigation
Assessment of antiemetic and modulatory activity of dihydrocoumarin on copper sulfate induced emetic chicks: An in vivo investigation Open
Dihydrocoumarin (DHC) is a natural compound found in plants like sweet clover and tonka beans, commonly used as a flavoring agent in food and as a fragrance in cosmetics. This study investigates the potential antiemetic properties of DHC u…
View article: Effects of <i>Ganoderma lucidum</i> Supplementation on Obesity and Metabolic Alterations Induced by High‐Carbohydrate‐High‐Fat Diet in Rats
Effects of <i>Ganoderma lucidum</i> Supplementation on Obesity and Metabolic Alterations Induced by High‐Carbohydrate‐High‐Fat Diet in Rats Open
Ganoderma lucidum (GL), commonly called Reishi mushroom, has been utilized in traditional medicine against multiple ailments including obesity and metabolic complications. The purpose of this study was to evaluate the ability of the powder…
View article: Protodioscin exerts antagonistic analgesic and antidiarrheal properties through the cyclooxygenase and µ-opioid receptor interaction pathways
Protodioscin exerts antagonistic analgesic and antidiarrheal properties through the cyclooxygenase and µ-opioid receptor interaction pathways Open
Protodioscin (PRO), a natural steroidal saponin, shows potential for treating pain and diarrhea due to its anti-inflammatory and analgesic properties. The study aims to investigate the analgesic and antidiarrheal effects of PRO, comparing …
View article: Antidiabetic potential of fenugreek (<i>Trigonella foenum‐graecum</i>): A magic herb for diabetes mellitus
Antidiabetic potential of fenugreek (<i>Trigonella foenum‐graecum</i>): A magic herb for diabetes mellitus Open
Fenugreek ( Trigonella foenum‐graecum ) is a widely grown dietary herb in Asia, and its seeds are traditionally used for several diseases, including diabetes. The seeds and leaves possess a variety of compounds that play an important role …
View article: A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant
A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant Open
Aegiceras corniculatum, commonly referred to as Khalsi, is a member of the mangrove Myrsinaceae family. The various parts of this plant have been used in traditional medicinal systems for their potential therapeutic effects in conditions s…
View article: SCREENING OF AGGLUTINATION ACTIVITIES OF COMMON VEGETABLES IN BANGLADESH
SCREENING OF AGGLUTINATION ACTIVITIES OF COMMON VEGETABLES IN BANGLADESH Open
Lectins are capable of cell agglutination by interacting with the cell surface exposed glycans. Lectins that agglutinate erythrocytes are called hemagglutinin. These compounds occur in various organisms including plants. In this study, twe…
View article: IN-VITRO STUDIES OF THE EFFECT OF ARSENIC ON THE BINDING OF METRONIDAZOLE AT THE BINDING SITES OF BOVINE SERUM ALBUMIN
IN-VITRO STUDIES OF THE EFFECT OF ARSENIC ON THE BINDING OF METRONIDAZOLE AT THE BINDING SITES OF BOVINE SERUM ALBUMIN Open
The effect of arsenic on the binding of metronidazole (an anti-amoebic agent) to bovine serum albumin (BSA) was studied by equilibrium dialysis (ED) method in order to justify the nature of binding capability of the drug and arsenic to BSA…
View article: Therapeutic Potential of Nelumbo nucifera (Sacred Lotus) in CNS Disorders
Therapeutic Potential of Nelumbo nucifera (Sacred Lotus) in CNS Disorders Open
Nelumbo nucifera (sacred lotus), locally known as Poddo, has been used as food and traditional remedy in Ayurvedic system in India and Traditional Chinese Medicine for a wide range of diseases. During past two decades, there are numerous s…
Phytochemical Evaluation and Pharmacological Activities of <i>Antidesma Montanum</i> Blume Leaf Extract Open
The demand for medicinal plants and their derived substances is increasing day by day due to their relevance in the context of drug discovery and development. The goal of this investigation is to assess the pharmacological and phytochemica…
Pesticidal Activity of Sundarban Mangrove Plant Extracts against Sitophilus Pests and Identification of Active Constituents Using LC-MS Open
Plants act as a rich source of novel natural pesticides. In the backdrop of the recent revival of interest in developing plant-based insecticides, this study was carried out to investigate the pesticidal activity of Sundarban mangrove plan…
Hepatoprotective Plants from Bangladesh: A Biophytochemical Review and Future Prospect Open
Liver diseases are quite prevalant in many densely populated countries, including Bangladesh. The liver and its hepatocytes are targeted by virus and microbes, as well as by chemical environmental toxicants, causing wide-spread disruption …
PROXIMATE COMPOSITION AND HPLC-DAD ANALYSIS OF BIOACTIVE POLYPHENOLS IN LEAFY VEGETABLES CONSUMED IN THE DIET FOUND IN SOUTHERN PART OF BANGLADESH Open
Four leafy vegetables, Phyla nodiflora, Amaranthus spinosus, Amaranthus viridis and Chenopodium album usually consumed by the Southern people of Bangladesh. In this study, we tested proximate composition and antioxidant potential of four l…
Amaranthus spinosus Attenuated Obesity-Induced Metabolic Disorders in High-Carbohydrate-High-Fat Diet-Fed Obese Rats Open
Amaranthus spinosus is a common vegetable of Bangladesh and well-known for its ethnomedicinal uses. In this study, we have evaluated the ability of powdered supplementation, methanol extract, and aqueous extract of A. spinosus in attenuati…
Antioxidant properties and phenolic profiling by UPLC-QTOF-MS of Ajwah, Safawy and Sukkari cultivars of date palm Open
Date palm (P. dactylifera) plays a vital role in ethnomedicinal practices in several parts of the world. There are over 2000 cultivars of date palm that differ in chemical composition and extent of bioactivity. The present study was undert…
Ethnobotany and Antimicrobial Peptides From Plants of the Solanaceae Family: An Update and Future Prospects Open
The Solanaceae is an important plant family that has been playing an essential role in traditional medicine and human nutrition. Members of the Solanaceae are rich in bioactive metabolites and have been used by different tribes around the …
A Systematic Review on Anti-diabetic and Cardioprotective Potential of Gallic Acid: A Widespread Dietary Phytoconstituent Open
Gallic acid (GA) is a bioactive phytoconstituent that has been reported to prevent a number of diseases. However, there is no systematic review to-date on its anti-diabetic and cardioprotective potential including molecular mechanisms for …
Molecular docking study of the phytol and its derivatives against COX-2 induced inflammation: A combined density functional study Open
This study aimed to determine the activity of PYT and its derivatives against COX-2, including 5IKR protein induced inflammation by using the computational tools. PYT and its derivatives have been designed by utilizing density functional t…
A systematic review on antioxidant and antiinflammatory activity of Sesame (<span><i>Sesamum indicum</i></span> L.) oil and further confirmation of antiinflammatory activity by chemical profiling and molecular docking Open
Traditionally, sesame oil (SO) has been used as a popular food and medicine. The review aims to summarize the antioxidant and antiinflammatory effects of SO and its identified compounds as well as further fatty acid profiling and molecular…
Agathisflavone: Botanical sources, therapeutic promises, and molecular docking study Open
In this article, we have summarized the biological sources and pharmacological activities of agathisflavone along with molecular docking studies to correlate the interaction of this biflavonoid and biomacromolecules involving in its biolog…
Analgesic Activity, Chemical Profiling and Computational Study on Chrysopogon aciculatus Open
Present study was undertaken to evaluate the analgesic activity of the ethanol extract of Chrysopogon aciculatus. In addition to bioassays in mice, chemical profiling was done by LC-MS and GC-MS to identify phytochemicals, which were furth…
Anticancer activity of thymol: A literature‐based review and docking study with Emphasis on its anticancer mechanisms Open
This review aims to summarize the anticancer effects of the natural monoterpene phenol derivative of cymenethymol and its derivatives as well as further molecular docking study to correlate the interaction of thymol and biomacromolecules t…
Biophysical characterization and structural determination of the potent cytotoxic<i>Psathyrella asperospora</i>lectin Open
A lectin with strong cytotoxic effect on human colon cancer HT29 and monkey kidney VERO cells was recently identified from the Australian indigenous mushroom Psathyrella asperospora and named PAL. We herein present its biochemical and stru…
Comparative study of neuropharmacological, analgesic properties and phenolic profile of Ajwah, Safawy and Sukkari cultivars of date palm (Phoenix dactylifera) Open
In addition to the rich nutritional value, date palm is also used in various ethnobotanical practices for the treatment of various disease conditions. Present investigation was undertaken to examine the neuropharmacological and antinocicep…