Rebecca N. Baergen
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View article: Releasing Placentas to Families: A Unified Recommendation From the Perinatal Committee of the Society for Pediatric Pathology
Releasing Placentas to Families: A Unified Recommendation From the Perinatal Committee of the Society for Pediatric Pathology Open
As perinatal pathologists, we acknowledge that some families would like to take their placenta home with them from the hospital for various sociocultural and/or religious beliefs and practices (eg, special burial, and, not uncommonly, cons…
View article: Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy
Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy Open
The effect of SARS-CoV-2 infection on placental function is not well understood. Analysis of placentas from women who tested positive at delivery showed SARS-CoV-2 genomic and subgenomic RNA in 22 out of 52 placentas. Placentas from two mo…
View article: SARS-CoV-2 and Placental Pathology: Malperfusion Patterns Are Dependent on Timing of Infection During Pregnancy.
SARS-CoV-2 and Placental Pathology: Malperfusion Patterns Are Dependent on Timing of Infection During Pregnancy. Open
The extent to which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection at different points in the pregnancy timeline may affect maternal and fetal outcomes remains unknown. We sought to characterize the impact of SARS-C…
View article: Placental pathology, neonatal birthweight and Apgar score in acute and distant SARS-CoV-2 infection
Placental pathology, neonatal birthweight and Apgar score in acute and distant SARS-CoV-2 infection Open
SARS-CoV-2 infection during pregnancy has demonstrable effects on the placenta with potential significant impacts for maternal and fetal health. Prevention of maternal SARS-CoV-2 infection, primarily through vaccination, remains the best m…
View article: Inflammatory Responses in the Placenta upon SARS-CoV-2 Infection Late in Pregnancy - IHC data
Inflammatory Responses in the Placenta upon SARS-CoV-2 Infection Late in Pregnancy - IHC data Open
SARS-CoV-2 infection during pregnancy does not affect the large majority of neonates but presents an increased risk for adverse pregnancy outcome. The effects of SARS-CoV-2 of its recently identified variants on placental function are not …
View article: Inflammatory Responses in the Placenta upon SARS-CoV-2 Infection Late in Pregnancy - IHC data
Inflammatory Responses in the Placenta upon SARS-CoV-2 Infection Late in Pregnancy - IHC data Open
SARS-CoV-2 infection during pregnancy does not affect the large majority of neonates but presents an increased risk for adverse pregnancy outcome. The effects of SARS-CoV-2 of its recently identified variants on placental function are not …
View article: SARS-CoV-2 Infects Syncytiotrophoblast and Activates Inflammatory Responses in the Placenta
SARS-CoV-2 Infects Syncytiotrophoblast and Activates Inflammatory Responses in the Placenta Open
SARS-CoV-2 infection during pregnancy leads to an increased risk of adverse pregnancy outcomes. Although the placenta itself can be a target of virus infection, most neonates are virus free and are born healthy or recover quickly. Here, we…
View article: Placental Pathology in COVID-19
Placental Pathology in COVID-19 Open
Objectives To describe histopathologic findings in the placentas of women with coronavirus disease 2019 (COVID-19) during pregnancy. Methods Pregnant women with COVID-19 delivering between March 18, 2020, and May 5, 2020, were identifie…
View article: Placental Pathology in Covid-19 Positive Mothers: Preliminary Findings
Placental Pathology in Covid-19 Positive Mothers: Preliminary Findings Open
This study describes the pathology and clinical information on 20 placentas whose mother tested positive for the novel Coronovirus (2019-nCoV) cases. Ten of the 20 cases showed some evidence of fetal vascular malperfusion or fetal vascular…
View article: Gestational choriocarcinoma
Gestational choriocarcinoma Open
The malignant transformation of trophoblast is interesting to contemplate, as trophoblast normally behaves in a manner that is interpreted as indicative of malignancy. First of all, trophoblasts show "controlled invasion" at the placental …
View article: Indications for submission and macroscopic examination of the placenta
Indications for submission and macroscopic examination of the placenta Open
The placenta is a fetal organ, composed of fetal DNA and as such reflects the fetal phenotype. The placenta consists of an umbilical cord, fetal membranes (amnion and chorion), and the placental disc which in turn is comprised of villous t…
View article: Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia
Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia Open
Preeclampsia (PE) is considered the leading cause of maternal and perinatal morbidity and mortality. The placenta seems to play an essential role in this disease, probably due to factors involved in its formation and development. The prese…