Rebecca S. LaRue
YOU?
Author Swipe
View article: C/EBPβ deletion in macrophages impairs mammary gland alveolar budding during the estrous cycle
C/EBPβ deletion in macrophages impairs mammary gland alveolar budding during the estrous cycle Open
Macrophages have important roles in mammary gland development and tissue homeostasis, but the specific mechanisms that regulate macrophage function need further elucidation. We have identified C/EBPβ as an important transcription factor ex…
View article: Nuclear corepressors NCOR1 and NCOR2 entrain thymocyte signaling, selection, and emigration
Nuclear corepressors NCOR1 and NCOR2 entrain thymocyte signaling, selection, and emigration Open
T cell development proceeds via discrete stages that require both gene induction and gene repression. Transcription factors direct gene repression by associating with corepressor complexes containing chromatin-remodeling enzymes; the corep…
View article: Scedosporium infection disseminated “from toe to head” in allogeneic stem cell transplant recipient: a case report
Scedosporium infection disseminated “from toe to head” in allogeneic stem cell transplant recipient: a case report Open
View article: Supplementary Figures 1 through 7 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy
Supplementary Figures 1 through 7 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy Open
PDF - 930K, Supplementary Figure 1. Individual modifications to culture medium yield a fraction of CD62L+ cells in extended culture Supplementary Figure 2. Cells cultured in cocktail containing medium have greater viability. Supplementary …
View article: Data from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy
Data from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy Open
Cytotoxic T cells typically are expanded ex vivo in culture with IL2 for adoptive immunotherapy. This culture period leads to a differentiated phenotype and acquisition of effector function, as well as a loss of in vivo proli…
View article: Data from <i>Sleeping Beauty</i> Screen Identifies <i>RREB1</i> and Other Genetic Drivers in Human B-cell Lymphoma
Data from <i>Sleeping Beauty</i> Screen Identifies <i>RREB1</i> and Other Genetic Drivers in Human B-cell Lymphoma Open
Follicular lymphoma and diffuse large B-cell lymphoma (DLBCL) are the most common non-Hodgkin lymphomas distinguishable by unique mutations, chromosomal rearrangements, and gene expression patterns. Here, it is demonstrated that early B-ce…
View article: Supplementary Table 1 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy
Supplementary Table 1 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy Open
XLSX - 35K, Supplementary Table 1. Upstream regulators predicted to be more activated in CD62L+CD44+ cocktail grown OT-I CD8 T cells versus sorted CD62L-CD44+ IL-2 grown OT-I CD8 T cells by transcriptional profiling.
View article: Supplementary Table 1 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy
Supplementary Table 1 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy Open
XLSX - 35K, Supplementary Table 1. Upstream regulators predicted to be more activated in CD62L+CD44+ cocktail grown OT-I CD8 T cells versus sorted CD62L-CD44+ IL-2 grown OT-I CD8 T cells by transcriptional profiling.
View article: Supplementary Table 2 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy
Supplementary Table 2 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy Open
XLSX - 276K, Supplementary Table 2. Differentially expressed genes between sorted populations of memory cocktail and IL-2 grown OT-I CD8 T cells.
View article: Supplemental Figures 1-10 from <i>Sleeping Beauty</i> Screen Identifies <i>RREB1</i> and Other Genetic Drivers in Human B-cell Lymphoma
Supplemental Figures 1-10 from <i>Sleeping Beauty</i> Screen Identifies <i>RREB1</i> and Other Genetic Drivers in Human B-cell Lymphoma Open
PDF with supplemental figures 1-10 with each containing a figure legend at the bottom fo the figure.
View article: Supplementary Table 2 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy
Supplementary Table 2 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy Open
XLSX - 276K, Supplementary Table 2. Differentially expressed genes between sorted populations of memory cocktail and IL-2 grown OT-I CD8 T cells.
View article: Data from <i>Sleeping Beauty</i> Screen Identifies <i>RREB1</i> and Other Genetic Drivers in Human B-cell Lymphoma
Data from <i>Sleeping Beauty</i> Screen Identifies <i>RREB1</i> and Other Genetic Drivers in Human B-cell Lymphoma Open
Follicular lymphoma and diffuse large B-cell lymphoma (DLBCL) are the most common non-Hodgkin lymphomas distinguishable by unique mutations, chromosomal rearrangements, and gene expression patterns. Here, it is demonstrated that early B-ce…
View article: Supplementary Figures 1 through 7 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy
Supplementary Figures 1 through 7 from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy Open
PDF - 930K, Supplementary Figure 1. Individual modifications to culture medium yield a fraction of CD62L+ cells in extended culture Supplementary Figure 2. Cells cultured in cocktail containing medium have greater viability. Supplementary …
View article: Supplemental Figures 1-10 from <i>Sleeping Beauty</i> Screen Identifies <i>RREB1</i> and Other Genetic Drivers in Human B-cell Lymphoma
Supplemental Figures 1-10 from <i>Sleeping Beauty</i> Screen Identifies <i>RREB1</i> and Other Genetic Drivers in Human B-cell Lymphoma Open
PDF with supplemental figures 1-10 with each containing a figure legend at the bottom fo the figure.
View article: Data from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy
Data from Antigen-Specific Culture of Memory-like CD8 T Cells for Adoptive Immunotherapy Open
Cytotoxic T cells typically are expanded ex vivo in culture with IL2 for adoptive immunotherapy. This culture period leads to a differentiated phenotype and acquisition of effector function, as well as a loss of in vivo proli…
View article: Data from Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma
Data from Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma Open
Multiple studies have identified transcriptome subtypes of high-grade serous ovarian carcinoma (HGSOC), but their interpretation and translation are complicated by tumor evolution and polyclonality accompanied by extensive accumulation of …
View article: Supplemental Table 6 from Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma
Supplemental Table 6 from Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma Open
Supplemental Table 6. Gene Cluster Expression Summary Scores. Tab 1 Human GCESS values Tab 2 Mouse GCESS values Tab 3 Dog GCESS values Tab 4 GSE212257 GCESS values
View article: Supplemental Table 2 from Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma
Supplemental Table 2 from Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma Open
Tumor Counts, number of Outcome events and GCESS Outcome threshold values
View article: Data from Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma
Data from Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma Open
Multiple studies have identified transcriptome subtypes of high-grade serous ovarian carcinoma (HGSOC), but their interpretation and translation are complicated by tumor evolution and polyclonality accompanied by extensive accumulation of …
View article: Supplementary Data and Figures from Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma
Supplementary Data and Figures from Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma Open
Supplementary methods contains additional information describing methods used and description of all supplemental data included. Supplemental Figures Supplemental Figure 1. Real human data clustered Supplemental Figure 2. Random human data…
View article: Data from Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia
Data from Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia Open
Standard chemotherapy for acute myeloid leukemia (AML) targets proliferative cells and efficiently induces complete remission; however, many patients relapse and die of their disease. Relapse is caused by leukemia stem cells (LSC), the cel…
View article: Supplementary Data from Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma
Supplementary Data from Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma Open
Supplementary Materials & Methods. Supplemental Tables 1-3 and Supplemental Figures 1-19.
View article: Figure S4 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset
Figure S4 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset Open
Figure S4 shows metastasis data following clodronate administration and characterization of lipid-loaded BMDMs.
View article: Supplementary Dataset 3 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset
Supplementary Dataset 3 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset Open
Gene set enrichment analysis of cluster 6 compared to gene sets from a published manuscript and MSigDB.
View article: Supplemental Table 4 from Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma
Supplemental Table 4 from Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma Open
Supplemental Table 4. Gene lists identified in the clustering. Tab 1 Genes in Human clusters (n=7), mouse clusters (n=11), dog clusters (n=5), GSE212257 (n=14) Tab 2 Overlap counts of RNASEQ cluster lists. Tab 3 Overlap of human cluster 1 …
View article: Supplementary Data from Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia
Supplementary Data from Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia Open
Supplementary Materials and Methods and Figures. Suppl Figs: SF1. Workflow; SF2: Cell Surface Markers; SF3: HSPC Markers; SF4: Human AML, SF5: Sorting Strategy, SF6: Post-sort; SF7: Viability and Immunophenotype; SF8: CD36 and CD69 in Huma…
View article: Data from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset
Data from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset Open
While macrophages are among the most abundant immune cell type found within primary and metastatic mammary tumors, how their complexity and heterogeneity change with metastatic progression remains unknown. Here, macrophages were isolated f…
View article: Tables 1-7 from Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia
Tables 1-7 from Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia Open
Supplementary Tables: ST1: Differentially Expressed Genes; ST2: IPA, ST3: Clinical Data, ST4: Mutational Profiles, ST5: qPCR Gene Panel, ST6: qPCR Enriched, ST7: NGS Gene panel
View article: Tables 1-7 from Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia
Tables 1-7 from Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia Open
Supplementary Tables: ST1: Differentially Expressed Genes; ST2: IPA, ST3: Clinical Data, ST4: Mutational Profiles, ST5: qPCR Gene Panel, ST6: qPCR Enriched, ST7: NGS Gene panel
View article: Supplementary Table S1 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset
Supplementary Table S1 from Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset Open
Table S1 shows the classification of the macrophage clusters identified by scRNA-seq.