Rebecca T. Ruck
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View article: Celebrating women in process research at MSD
Celebrating women in process research at MSD Open
View article: Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back
Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back Open
ADVERTISEMENT RETURN TO ARTICLES ASAPEditorialNEXTEmpowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting BackElinor H. Cantor*Elinor H. CantorPhiladelphia Chapter, Association for Women in Science, Phoenixville…
View article: Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back
Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back Open
ADVERTISEMENT RETURN TO ISSUEPREVEditorialNEXTEmpowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting BackElinor H. Cantor*Elinor H. CantorPhiladelphia Chapter, Association for Women in Science, Phoenixville, Pe…
View article: Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back
Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back Open
ADVERTISEMENT RETURN TO ARTICLES ASAPEditorialNEXTEmpowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting BackElinor H. CantorElinor H. CantorMore by Elinor H. Cantor, Margaret M. FaulMargaret M. FaulMore by Mar…
View article: The Catalysis Laboratory at Merck: 20 Years of Catalyzing Innovation
The Catalysis Laboratory at Merck: 20 Years of Catalyzing Innovation Open
The Catalysis Laboratory at Merck was established in 2002 to discover and develop asymmetric hydrogenation transformations for application to the company's pipeline. Twenty years later, it is safe to say that not only was what now feels li…
View article: Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods
Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods Open
An efficient route to the HCV antiviral agent uprifosbuvir was developed in 5 steps from readily available uridine in 50% overall yield.
View article: Eric Jacobsen and Gender Diversity in Organic Chemistry
Eric Jacobsen and Gender Diversity in Organic Chemistry Open
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View article: Gender Diversity in Process Chemistry
Gender Diversity in Process Chemistry Open
ADVERTISEMENT RETURN TO ISSUEEditorialNEXTGender Diversity in Process ChemistryRebecca T. Ruck*Rebecca T. RuckMRL, Merck & Co., Inc., 126 East Lincoln Avenue, Rahway, New Jersey 07065, United States*E-mail: [email protected]. Telephone: 73…
View article: CCDC 1865869: Experimental Crystal Structure Determination
CCDC 1865869: Experimental Crystal Structure Determination Open
View article: CCDC 1586349: Experimental Crystal Structure Determination
CCDC 1586349: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1529293: Experimental Crystal Structure Determination
CCDC 1529293: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1529294: Experimental Crystal Structure Determination
CCDC 1529294: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1586348: Experimental Crystal Structure Determination
CCDC 1586348: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1529292: Experimental Crystal Structure Determination
CCDC 1529292: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1512974: Experimental Crystal Structure Determination
CCDC 1512974: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1523527: Experimental Crystal Structure Determination
CCDC 1523527: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1525737: Experimental Crystal Structure Determination
CCDC 1525737: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1512975: Experimental Crystal Structure Determination
CCDC 1512975: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1525797: Experimental Crystal Structure Determination
CCDC 1525797: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1525736: Experimental Crystal Structure Determination
CCDC 1525736: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1512973: Experimental Crystal Structure Determination
CCDC 1512973: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: The protecting-group free selective 3′-functionalization of nucleosides
The protecting-group free selective 3′-functionalization of nucleosides Open
The direct and chemoselective 3′-phosphoramidation, phosphorylation and acylation of nucleosides are described.
View article: CCDC 1523526: Experimental Crystal Structure Determination
CCDC 1523526: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1523528: Experimental Crystal Structure Determination
CCDC 1523528: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions
A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions Open
Detailed mechanistic studies of a Pd-catalyzed asymmetric C–N coupling led to a rational design of a new series of bis-phosphine mono-oxides ligated Pd(ii) pre-catalysts that allow for reliable and complete catalyst activation.
View article: Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor
Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor Open
We have been focused on identifying a structurally different next generation inhibitor to MK-5172 (our Ns3/4a protease inhibitor currently under regulatory review), which would achieve superior pangenotypic activity with acceptable safety …