Reed Chen
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View article: Finite element analysis of a neural implant for cytostatic hypothermia and a novel heat management system
Finite element analysis of a neural implant for cytostatic hypothermia and a novel heat management system Open
The treatment of glioblastoma (GBM) presents significant challenges, with median survival rates remaining low despite standard-of-care therapies. A novel approach, cytostatic hypothermia (CH), is under development against GBM; it is a wind…
View article: Emulating Clinical Quality Muscle B-mode Ultrasound Images from Plane Wave Images Using a Two-Stage Machine Learning Model
Emulating Clinical Quality Muscle B-mode Ultrasound Images from Plane Wave Images Using a Two-Stage Machine Learning Model Open
Research ultrasound scanners such as the Verasonics Vantage often lack the advanced image processing algorithms used by clinical systems. Image quality is even lower in plane wave imaging - often used for shear wave elasticity imaging (SWE…
View article: EXTH-74. COOLING GLIOBLASTOMA WITH A NEURAL IMPLANT
EXTH-74. COOLING GLIOBLASTOMA WITH A NEURAL IMPLANT Open
Survival rates for glioblastoma (GBM) patients are low due to the difficulty in eradicating all tumor cells, leading to frequent recurrence. This recurrence is frequently within 2-cm from the original site. Studies indicate that supra-tota…
View article: Finite element analysis of a neural implant for cytostatic hypothermia and a novel heat management system
Finite element analysis of a neural implant for cytostatic hypothermia and a novel heat management system Open
The treatment of glioblastoma (GBM) presents significant challenges, with median survival rates remaining low despite standard-of-care therapies. This study expands upon the findings of a novel approach to managing GBM, namely cytostatic h…
View article: EXTH-04. CYTOSTATIC HYPOTHERMIA AGAINST GLIOBLASTOMA AND THE DEVELOPMENT OF A NEURAL IMPLANT FOR RODENTS AND SWINE
EXTH-04. CYTOSTATIC HYPOTHERMIA AGAINST GLIOBLASTOMA AND THE DEVELOPMENT OF A NEURAL IMPLANT FOR RODENTS AND SWINE Open
Survival rates for patients with glioblastoma (GBM) remain discouraging due to the near-impossibility of eradicating all tumor cells, resulting in frequent recurrence. However, studies have shown that recurrence is predominantly localized …
View article: Cytostatic hypothermia and its impact on glioblastoma and survival
Cytostatic hypothermia and its impact on glioblastoma and survival Open
Patients with glioblastoma (GBM) have limited options and require novel approaches to treatment. Here, we studied and deployed nonfreezing “cytostatic” hypothermia to stunt GBM growth. This growth-halting method contrasts with ablative, cr…
View article: Cytostatic hypothermia and its impact on glioblastoma and survival
Cytostatic hypothermia and its impact on glioblastoma and survival Open
Novel therapeutic approaches are needed for patients with glioblastoma (GBM) who otherwise have limited options. Here we studied and deployed non-freezing ‘cytostatic’ hypothermia to stunt GBM growth. This contrasts with ablative, cryogeni…
View article: Cryo-ZSSR: multiple-image super-resolution based on deep internal learning
Cryo-ZSSR: multiple-image super-resolution based on deep internal learning Open
Single-particle cryo-electron microscopy (cryo-EM) is an emerging imaging modality capable of visualizing proteins and macro-molecular complexes at near-atomic resolution. The low electron-doses used to prevent sample radiation damage, res…