Reem Malouf
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View article: Behavioural and cognitive changes in young adults towards food and nutrition after exposure to digital food communication: a mixed-methods systematic review
Behavioural and cognitive changes in young adults towards food and nutrition after exposure to digital food communication: a mixed-methods systematic review Open
View article: Perioperative immunotherapy strategies for resectable non-small cell lung cancer
Perioperative immunotherapy strategies for resectable non-small cell lung cancer Open
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To compare, via a network meta-analysis, the effectiveness and safety of different immunotherapy agents that are administered in a perioperative settin…
View article: Prognosis of surgically resected clinical stage 1A non-small cell lung cancers manifesting as a subsolid nodule on computed tomography including pure ground glass nodules
Prognosis of surgically resected clinical stage 1A non-small cell lung cancers manifesting as a subsolid nodule on computed tomography including pure ground glass nodules Open
This is a protocol for a Cochrane Review (prognosis). The objectives are as follows: To quantify the risk of tumour relapse/recurrence after a surgical resection of stage 1A non-small cell lung cancer (NSCLC) as manifested on computed tomo…
View article: Prognostic value of blood eosinophils for predicting survival and treatment outcomes in people with non-small cell lung cancer
Prognostic value of blood eosinophils for predicting survival and treatment outcomes in people with non-small cell lung cancer Open
This is a protocol for a Cochrane Review (prognosis). The objectives are as follows: To assess the prognostic value of measuring pretreatment baseline blood eosinophil levels in adults receiving systemic treatment for any stage of non-smal…
View article: Association of current Schistosoma mansoni, Schistosoma japonicum, and Schistosoma mekongi infection status and intensity with periportal fibrosis: a systematic review and meta-analysis
Association of current Schistosoma mansoni, Schistosoma japonicum, and Schistosoma mekongi infection status and intensity with periportal fibrosis: a systematic review and meta-analysis Open
Nuffield Department of Population Health Pump Priming Fund, Wellcome Trust Institutional Strategic Support Fund, John Fell Fund, Robertson Foundation, and UK Research and Innovation Engineering and Physical Sciences Research Council.
View article: Immune checkpoint inhibitors plus platinum-based chemotherapy compared to platinum-based chemotherapy with or without bevacizumab for first-line treatment of older people with advanced non-small cell lung cancer
Immune checkpoint inhibitors plus platinum-based chemotherapy compared to platinum-based chemotherapy with or without bevacizumab for first-line treatment of older people with advanced non-small cell lung cancer Open
Compared to platinum-based chemotherapy alone, adding ICIs to platinum-based chemotherapy probably leads to higher overall survival and progression-free survival, without an increase in treatment-related adverse events (grade 3 or higher),…
View article: Overall prognosis of index lung cancer recurrence or of second primary lung cancer in people with non-small cell lung cancer operated with complete resection
Overall prognosis of index lung cancer recurrence or of second primary lung cancer in people with non-small cell lung cancer operated with complete resection Open
This is a protocol for a Cochrane Review (prognosis). The objectives are as follows: We aim to compare overall survival in people with recurrence and second primary lung cancer (SPLC) after lung cancer surgery. If survival differs between …
View article: Factors associated with posttraumatic stress and anxiety among the parents of babies admitted to neonatal care: a systematic review
Factors associated with posttraumatic stress and anxiety among the parents of babies admitted to neonatal care: a systematic review Open
Background Posttraumatic stress (PTS) and anxiety are common mental health problems among parents of babies admitted to a neonatal unit (NNU). This review aimed to identify sociodemographic, pregnancy and birth, and psychological factors a…
View article: Association of current<i>Schistosoma mansoni, S. japonicum,</i>and<i>S. mekongi</i>infection status and intensity with periportal fibrosis: a systematic review and meta-analysis
Association of current<i>Schistosoma mansoni, S. japonicum,</i>and<i>S. mekongi</i>infection status and intensity with periportal fibrosis: a systematic review and meta-analysis Open
Summary Background Periportal fibrosis (PPF) is a severe morbidity caused by both current and past exposure to intestinal schistosomes. We assessed the association between current/active infection status and intensity of Schistosoma manson…
View article: Brain health measurement: a scoping review
Brain health measurement: a scoping review Open
Objectives Preservation of brain health is an urgent priority for the world’s ageing population. The evidence base for brain health optimisation strategies is rapidly expanding, but clear recommendations have been limited by heterogeneity …
View article: Body Composition and Risk of Incident Heart Failure in 1 Million Adults: A Systematic Review and Dose–Response Meta‐Analysis of Prospective Cohort Studies
Body Composition and Risk of Incident Heart Failure in 1 Million Adults: A Systematic Review and Dose–Response Meta‐Analysis of Prospective Cohort Studies Open
Background The aim of this systematic review was to quantify the associations between body composition measures and risk of incident heart failure (HF) and its subtypes in the general population. Methods and Results We searched Medline, Em…
View article: Correlates of chronic hepatitis B virus infection in the general adult population of China: Systematic review and meta‐analysis
Correlates of chronic hepatitis B virus infection in the general adult population of China: Systematic review and meta‐analysis Open
Chronic infection with hepatitis B virus (HBV) is a significant public health issue in China. Understanding factors associated with chronic HBV is important to enable targeted screening and education and to improve early diagnosis and prev…
View article: Impact of low-dose computed tomography (LDCT) screening on lung cancer-related mortality
Impact of low-dose computed tomography (LDCT) screening on lung cancer-related mortality Open
We performed the search in collaboration with the Information Specialist of the Cochrane Lung Cancer Group and included the Cochrane Lung Cancer Group Trial Register, Cochrane Central Register of Controlled Trials (CENTRAL, the Cochrane Li…
View article: Prevalence of anxiety and post-traumatic stress (PTS) among the parents of babies admitted to neonatal units: A systematic review and meta-analysis
Prevalence of anxiety and post-traumatic stress (PTS) among the parents of babies admitted to neonatal units: A systematic review and meta-analysis Open
This research is funded by the National Institute for Health Research (NIHR) Policy Research Programme, conducted through the Policy Research Unit in Maternal and Neonatal Health and Care, PR-PRU-1217-21202. The views expressed are those o…
View article: Body composition and risk of heart failure: protocol for a systematic review and meta-analysis
Body composition and risk of heart failure: protocol for a systematic review and meta-analysis Open
Introduction Although there is strong evidence of an association between general adiposity and incidence of heart failure, previous systematic reviews and meta-analyses have not reliably assessed the association of heart failure risk with …
View article: The top 10 research priorities in diabetes and pregnancy according to women, support networks and healthcare professionals
The top 10 research priorities in diabetes and pregnancy according to women, support networks and healthcare professionals Open
Aims To undertake a Priority Setting Partnership (PSP) to establish priorities for future research in diabetes and pregnancy, according to women with experience of pregnancy, and planning pregnancy, with any type of diabetes, their support…
View article: Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevacizumab for people with advanced non-small cell lung cancer
Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevacizumab for people with advanced non-small cell lung cancer Open
Authors' conclusions The evidence in this review suggests that single-agent ICI in people with NSCLC and PD-L1 ≥50% probably leads to a higher overall survival rate and may lead to a higher progression-free survival and overall response ra…
View article: Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevacizumab for people with advanced non-small cell lung cancer
Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevacizumab for people with advanced non-small cell lung cancer Open
Authors' conclusions The evidence in this review suggests that single-agent ICI in people with NSCLC and PD-L1 ≥50% probably leads to a higher overall survival rate and may lead to a higher progression-free survival and overall response ra…
View article: Impact of obstetric unit closures, travel time and distance to obstetric services on maternal and neonatal outcomes in high-income countries: a systematic review
Impact of obstetric unit closures, travel time and distance to obstetric services on maternal and neonatal outcomes in high-income countries: a systematic review Open
Objectives To systematically review (1) The effect of obstetric unit (OU) closures on maternal and neonatal outcomes and (2) The association between travel distance/time to an OU and maternal and neonatal outcomes. Design Systematic review…
View article: First-Time Mothers’ Expectations and Experiences of Postnatal Care in England
First-Time Mothers’ Expectations and Experiences of Postnatal Care in England Open
Postnatal care is the aspect of maternity care with which women in England are least satisfied. Little is known about first-time mothers’ expectations of postnatal care, or how these expectations relate to their experiences and appraisal o…
View article: Women's ideal and real expectations of postnatal care during their first pregnancy: An online survey in England
Women's ideal and real expectations of postnatal care during their first pregnancy: An online survey in England Open
View article: First time mothers’ expectations and experiences of postnatal care in England: a longitudinal qualitative descriptive study
First time mothers’ expectations and experiences of postnatal care in England: a longitudinal qualitative descriptive study Open
Background: Effective postnatal care can support a safe and confident transition to parenthood, but it is the aspect of maternity care with which women in England are least satisfied. Little is known about first time mothers’ expectations …
View article: Expectations and experiences of hospital postnatal care in the UK: a systematic review of quantitative and qualitative studies
Expectations and experiences of hospital postnatal care in the UK: a systematic review of quantitative and qualitative studies Open
Objectives To report on women’s and families’ expectations and experiences of hospital postnatal care, and also to reflect on women’s satisfaction with hospital postnatal care and to relate their expectations to their actual care experienc…
View article: Prophylactic platelet transfusions prior to surgery for people with a low platelet count
Prophylactic platelet transfusions prior to surgery for people with a low platelet count Open
Background People with thrombocytopenia often require a surgical procedure. A low platelet count is a relative contraindication to surgery due to the risk of bleeding. Platelet transfusions are used in clinical practice to prevent and trea…
View article: Antidepressants for treating depression in dementia
Antidepressants for treating depression in dementia Open
BackgroundThe use of antidepressants in dementia accompanied by depressive symptoms is widespread, but their clinical efficacy is uncertain. This review updates an earlier version, first published in 2002.ObjectivesTo determine the efficac…
View article: Comparison of a therapeutic-only versus prophylactic platelet transfusion policy for people with congenital or acquired bone marrow failure disorders
Comparison of a therapeutic-only versus prophylactic platelet transfusion policy for people with congenital or acquired bone marrow failure disorders Open
We found no evidence to determine the safety and efficacy of therapeutic platelet transfusion compared with prophylactic platelet transfusion for people with long-term bone marrow failure disorders. This review underscores the urgency of p…
View article: Prophylactic platelet transfusions prior to surgery for people with a low platelet count
Prophylactic platelet transfusions prior to surgery for people with a low platelet count Open
Findings of this review were based on three small trials involving minor surgery in adults with thrombocytopenia. We found insufficient evidence to recommend the administration of preprocedure prophylactic platelet transfusions in this sit…
View article: Pathogen-reduced platelets for the prevention of bleeding
Pathogen-reduced platelets for the prevention of bleeding Open
Findings from this review were based on 12 trials, and of the 1981 participants who received a platelet transfusion only 44 did not have a haematological or oncological diagnosis.In people with haematological or oncological disorders who a…
View article: Access and quality of maternity care for disabled women during pregnancy, birth and the postnatal period in England: data from a national survey
Access and quality of maternity care for disabled women during pregnancy, birth and the postnatal period in England: data from a national survey Open
Objectives More disabled women are becoming mothers, and yet, their care is rarely the focus of quantitative research. This study aimed to investigate access and quality of maternity care for women with differing disabilities. Design Secon…
View article: What influences birth place preferences, choices and decision-making amongst healthy women with straightforward pregnancies in the UK? A qualitative evidence synthesis using a ‘best fit’ framework approach
What influences birth place preferences, choices and decision-making amongst healthy women with straightforward pregnancies in the UK? A qualitative evidence synthesis using a ‘best fit’ framework approach Open