Explanipedia

Optimizing the Workflow of Superficial Temporal Artery Mapping in Extracranial-Intracranial Bypass Surgery Using Mixed Reality: A Proof-of-Concept Study Open

Shovan Bhatia, Anne Huynh, Regan M. Shanahan, Michael R. Kann, A. Gopakumar , et al. · 2025

MR provides comparable STA mapping accuracy to Doppler while reducing the mapping time. These findings suggest that the planned incision is unlikely to differ, providing early evidence for the feasibility of MR-guided mapping for EC-IC byp…

Improving prognostic models of six-month clinical outcomes after severe traumatic brain injury with daily inpatient biomarkers: A Bayesian modelling approach Open

Shawn R. Eagle, Regan M. Shanahan, Jae‐Yong Shim, Anna L. Slingerland, Shovan Bhatia , et al. · 2025

Biomarkers typically collected as part of inpatient clinical workups over the first two weeks post-injury improved discrimination of unfavorable outcomes and mortality by six-months compared to IMPACT.

Freehand ventricular catheter placement in ventriculoperitoneal shunt surgery is associated with higher rates of proximal catheter failure compared to image guidance Open

Nikhil Sharma, Jeffery Head, Regan M. Shanahan, Shovan Bhatia, Michael R. Kann , et al. · 2025

Objective: Ventricular catheter (VC) revision due to proximal catheter failure is a well-known but potentially avoidable complication of ventriculoperitoneal shunting (VPS). Anatomical “freehand” VC placement is still commonplace, despite …

Calvarial Biopsy Using Augmented Reality Technology: A Case Report and Technical Note Open

Nikhil Sharma, Regan M. Shanahan, Shovan Bhatia, Michael R. Kann, Anthony Tang , et al. · 2025

Calvarial lesions are uncommonly encountered and are often a slow and progressive process. Biopsies of calvarial lesions can be uniquely challenging due to its proximity to critical structures. Augmented reality (AR) offers a potential alt…

Pharmaceutical Modulation of Intracranial Aneurysm Development and Rupture Open

Alex Crane, Regan M. Shanahan, Joseph S. Hudson, Kamil W. Nowicki, Zachary C. Gersey , et al. · 2024

Management of intracranial aneurysms (IAs) is determined by patient age, risk of rupture, and comorbid conditions. While endovascular and microsurgical interventions offer solutions to mitigate the risk of rupture, pharmacological manageme…

Preinjury Frailty Predicts 1-Year Mortality in Older Adults With Traumatic Spine Fractures Open

Daryl P. Fields, Gregory Varga, Ali Alattar, Regan M. Shanahan, Ashtah Das , et al. · 2024

BACKGROUND AND OBJECTIVES: Nearly 30% of older adults presenting with isolated spine fractures will die within 1 year. Attempts to ameliorate this alarming statistic are hindered by our inability to identify relevant risk factors. The prim…

Single institution series describing external ventricular drain (EVD) placement and short- and long-term complications related to placement accuracy Open

Nikhil Sharma, Jeffery Head, Arka N. Mallela, Regan M. Shanahan, Stephen P. Canton , et al. · 2024

Background: The placement of an external ventricular drain (EVD) for the treatment of acute hydrocephalus is one of the most common life-saving procedures that neurosurgeons perform worldwide. There are many well-known complications associ…

Atlantoaxial Facet Fixation Using Cervical Facet Cage: Technical Case Report and Review of the Literature Open

Sharath Kumar Anand, Regan M. Shanahan, Ali Alattar, H. Westley Phillips, David O. Okonkwo , et al. · 2024

In 1994, the use of interfacet spacer placement was for joint distraction, reduction, and fusion to supplement atlantoaxial or occipitocervical fixation. Here we present a unique case of bilateral atlantoaxial interfacet fixation using cer…

Sex-specific molecular differences in glioblastoma: assessing the clinical significance of genetic variants Open

Nicolina Jovanovich, Ahmed Habib, Akanksha Chilukuri, N. U. Farrukh Hameed, Hansen Deng , et al. · 2024

Introduction Glioblastoma multiforme (GBM) is one of the most aggressive types of brain cancer, and despite rigorous research, patient prognosis remains poor. The characterization of sex-specific differences in incidence and overall surviv…

Surgical management of metastatic Hürthle cell carcinoma to the skull base, cortex, and spine: illustrative case Open

Nazia Hameed, Meagan Hoppe, Ahmed Habib, Jeffrey Head, Regan M. Shanahan , et al. · 2023

BACKGROUND Hürthle cell carcinoma (HCC) is an unusual and aggressive variant of the follicular type of differentiated thyroid cancer (DTC), accounting for less than 3% of DTCs but posing the highest risk of metastasis. Brain metastases are…

Infant Rudimentary Meningocele with Tethering of the Cervical Cord: A Case Report Open

Regan M. Shanahan, Joseph S. Hudson, Sakibul Huq, Aimé Parra Legarreta, Daryl P. Fields , et al. · 2023

Rudimentary meningoceles of the spine with dural extension are very rare and warrant surgical excision to prevent infection and long-term neurological deficits in pediatric patients. We present the case of a 5-month-old infant with a tethe…

Comparing Continuous versus Intermittent-Threshold Drainage Strategies for Spinal Perfusion Pressure Optimization in Patients with Acute Traumatic Spinal Cord Injuries Open

Raj Swaroop Lavadi, Regan M. Shanahan, D. Kojo Hamilton, Thomas J. Buell, Nitin Agarwal , et al. · 2023

Study Design A cross-sectional study. Objective The primary objective of this study is to compare the efficacy of continuous versus threshold drainage strategies for maintaining spinal cord perfusion pressure (SCPP) in patients with new tr…

XRT-04. THE ROLE OF STEREOTACTIC RADIOSURGERY FOR MENINGIOMAS IN PEDIATRIC PATIENTS Open

Regan M. Shanahan, Zhishuo Wei, Tracy K. Miller, Hansen Deng, Ajay Niranjan , et al. · 2023

Despite the generally benign and slow-growing nature, meningiomas in pediatric populations often exhibit more aggressive behavior. Stereotactic radiosurgery (SRS) is a non-invasive modality that is widely used as an upfront or adjuvant tre…

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