Ryo� Saito
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View article: Disease Duration of Urticaria: A Sub‐Analysis of a Survey on Subtypes and Clinical Characteristics of 1061 Patients With Urticaria in the Primary Care Institutes in Japan
Disease Duration of Urticaria: A Sub‐Analysis of a Survey on Subtypes and Clinical Characteristics of 1061 Patients With Urticaria in the Primary Care Institutes in Japan Open
Disease duration of urticaria is variable from days to decades. However, the mechanism of persistence for urticaria is largely unknown. To investigate factors which relate to the prognosis of urticaria, we conducted a cross‐sectional analy…
View article: Novel Methylation‐Based Model for Accurate Diagnosis of Upper Mediastinal Lymph Node Metastasis in Esophagogastric Junction Adenocarcinoma
Novel Methylation‐Based Model for Accurate Diagnosis of Upper Mediastinal Lymph Node Metastasis in Esophagogastric Junction Adenocarcinoma Open
Even after surgical resection, the prognosis is poor for patients with esophagogastric junction adenocarcinoma who develop upper mediastinal lymph node metastasis. Moreover, the current preoperative diagnostic accuracy for upper mediastina…
View article: Incidence rates of post-pancreatectomy complications are similar between octogenarians and non-octogenarians and decrease after minimally invasive pancreatic surgery : a retrospective cohort study
Incidence rates of post-pancreatectomy complications are similar between octogenarians and non-octogenarians and decrease after minimally invasive pancreatic surgery : a retrospective cohort study Open
View article: miR‑100‑5p and miR‑203a‑3p suppress esophageal squamous cell carcinoma progression by targeting FKBP5
miR‑100‑5p and miR‑203a‑3p suppress esophageal squamous cell carcinoma progression by targeting FKBP5 Open
Poorly differentiated cancers, including esophageal squamous cell carcinoma (ESCC), exhibit higher malignant potential and worse prognoses than well‑differentiated types. The present study aimed to identify microRNAs (miRNAs or miRs) invol…
View article: A case of an infant with eating disorder associated with lip incompetence due to congenital Blandin-Nuhn cyst
A case of an infant with eating disorder associated with lip incompetence due to congenital Blandin-Nuhn cyst Open
View article: Decoding Spine Nanostructure in Mental Disorders Reveals a Schizophrenia-Linked Role for Ecrg4
Decoding Spine Nanostructure in Mental Disorders Reveals a Schizophrenia-Linked Role for Ecrg4 Open
Dendritic spine dysfunction may contribute to the etiology and symptom expression of neuropsychiatric disorders. The intimate relationship between spine morphology and function suggests that decoding disease-related abnormalities from spin…
View article: Potential of Platelet‐Based Drug Delivery System for Treating Peritoneal Metastasis of Gastric Cancer
Potential of Platelet‐Based Drug Delivery System for Treating Peritoneal Metastasis of Gastric Cancer Open
Peritoneal metastasis is a lethal manifestation of gastric cancer, with poor prognosis and limited treatment options. A targeted drug delivery system minimizing systemic toxicity is urgently needed. Given that platelets form stable aggrega…
View article: Clinical Characteristics and Risk Factors for Cutaneous Manifestations Associated With Nemolizumab in Atopic Dermatitis: A Multicenter Retrospective Study in Japan
Clinical Characteristics and Risk Factors for Cutaneous Manifestations Associated With Nemolizumab in Atopic Dermatitis: A Multicenter Retrospective Study in Japan Open
Nemolizumab, an anti‐interleukin‐31 receptor A monoclonal antibody, has been approved in Japan for treating atopic dermatitis (AD)‐associated pruritus. While it is effective for itch control, nemolizumab‐associated cutaneous adverse events…
View article: 0068 Skin eruption shape-based pathological state inference for personalized treatment in chronic spontaneous urticaria
0068 Skin eruption shape-based pathological state inference for personalized treatment in chronic spontaneous urticaria Open
View article: Oncostatin M enhances the lengthening of sensory nerves and skin hypersensitivity
Oncostatin M enhances the lengthening of sensory nerves and skin hypersensitivity Open
Background Oncostatin M (OSM) is a cytokine that mediates inflammatory processes and is overexpressed in skin lesions of atopic dermatitis (AD). By amplifying neural responses to chemicals such as histamine, OSM increases sensitivity to pr…
View article: Comparative study of feline spinal cord tumors for distinction between peripheral nerve sheath tumor and meningioma
Comparative study of feline spinal cord tumors for distinction between peripheral nerve sheath tumor and meningioma Open
Peripheral nerve sheath tumors (PNSTs) and meningiomas in feline spinal canal are sometimes difficult to differentiate solely on the basis of histopathology. In this study, immunohistochemical markers for differentiating PNSTs from meningi…
View article: Mechanical Thrombectomy for Acute Medium Vessel Occlusion Because of Paradoxical Cerebral Embolism in a Patient with a Right Aortic Arch: A Case Report
Mechanical Thrombectomy for Acute Medium Vessel Occlusion Because of Paradoxical Cerebral Embolism in a Patient with a Right Aortic Arch: A Case Report Open
Access to the left common carotid artery in right aortic arch cases can be anatomically challenging. Preoperative imaging evaluation of the access route is crucial for quick and safe mechanical thrombectomy.
View article: Gastric T-cell lymphoma in a European wolf (<i>Canis lupus lupus</i>)
Gastric T-cell lymphoma in a European wolf (<i>Canis lupus lupus</i>) Open
A 15-year and 7-month-old male European wolf kept in a zoological park since birth, became emaciated and died. At necropsy, the gastric and mesenteric lymph nodes were enlarged, and perforation was observed in the stomach. Histopathologica…
View article: A case of AA amyloidosis with biliary cystadenoma and cervical thymoma in a striped skunk (<i>Mephitis mephitis</i>)
A case of AA amyloidosis with biliary cystadenoma and cervical thymoma in a striped skunk (<i>Mephitis mephitis</i>) Open
A 6-year and 11-months-old male striped skunk, Mephitis mephitis, showed inappetence and died. Necropsy revealed multiple hepatic masses, an enlarged spleen, wedge-shaped lesions in the kidneys, and a cervical cyst with white nodules. Hist…
View article: Comparison of the influence of postoperative oral nutritional supplementation between octogenarian and non-octogenarian patients undergoing gastrectomy for cancer
Comparison of the influence of postoperative oral nutritional supplementation between octogenarian and non-octogenarian patients undergoing gastrectomy for cancer Open
Postoperative ONS could prevent body weight loss, malnutrition, and sarcopenia especially in octogenarian patients who underwent gastrectomy for gastric cancer.
View article: 335. IMPACT OF POSTOPERATIVE COMPLICATIONS ON LONG-TERM OUTCOMES AFTER ESOPHAGECTOMY
335. IMPACT OF POSTOPERATIVE COMPLICATIONS ON LONG-TERM OUTCOMES AFTER ESOPHAGECTOMY Open
Background Recently, it has been reported that postoperative complications after esophagectomy not only prolong hospital stay and reduce quality of life, but also have impact on the long-term outcomes. However, this still remains controver…
View article: 270. ANALYSIS OF THE RELATIONSHIP BETWEEN CARDIAC DIAMETER AND ANASTOMOTIC TROUBLE IN TRANS HIATAL ESOPHAGOGASTRIC JUNCTION CANCER SURGERY
270. ANALYSIS OF THE RELATIONSHIP BETWEEN CARDIAC DIAMETER AND ANASTOMOTIC TROUBLE IN TRANS HIATAL ESOPHAGOGASTRIC JUNCTION CANCER SURGERY Open
Background The number of esophagogastric junction (EGJ) cancers has been increasing in recent years, and the trans hiatal lower esophagectomy is widely used for cases with shorter esophageal invasion. However, the mediastinal surgical view…
View article: Hyperactive mTORC1 in striatum dysregulates dopamine receptor expression and odor preference behavior
Hyperactive mTORC1 in striatum dysregulates dopamine receptor expression and odor preference behavior Open
Mechanistic target of rapamycin (mTOR) plays an important role in brain development and synaptic plasticity. Dysregulation of the mTOR pathway is observed in various human central nervous system diseases, including tuberous sclerosis compl…
View article: Laparoscopic Transhiatal Resection of an Esophageal Diverticulum in a Patient With Systemic Lupus Erythematosus: A Case Report
Laparoscopic Transhiatal Resection of an Esophageal Diverticulum in a Patient With Systemic Lupus Erythematosus: A Case Report Open
Esophageal diverticula are relatively uncommon, especially supradiaphragmatic diverticula. Esophageal diverticula are normally managed by observation; however, surgical treatment is sometimes indicated for large diverticula or diverticula …
View article: The Japanese vision for the Black Hole Explorer mission
The Japanese vision for the Black Hole Explorer mission Open
Akiyama, Kazunori et al.-- Full list of authors: Akiyama, Kazunori; Niinuma, Kotaro; Hada, Kazuhiro; Doi, Akihiro; Hagiwara, Yoshiaki; Higuchi, Aya E.; Honma, Mareki; Kawashima, Tomohisa; Kolev, Dimitar; Koyama, Shoko; Masui, Sho; Ohsuga, …
View article: Molecular mechanisms driving the interactions between platelet and gastric cancer cells during peritoneal dissemination
Molecular mechanisms driving the interactions between platelet and gastric cancer cells during peritoneal dissemination Open
Platelets (PLTs) facilitate tumor progression and the spread of metastasis. They also interact with cancer cells in various cancer types. Furthermore, PLTs form complexes with gastric cancer (GC) cells via direct contact and promote their …
View article: Evaluation of the validity of pancreatoduodenectomy in older patients with distal cholangiocarcinoma in terms of recurrence
Evaluation of the validity of pancreatoduodenectomy in older patients with distal cholangiocarcinoma in terms of recurrence Open
Background This retrospective study investigated the validity of pancreatoduodenectomy (PD) with regard to recurrence in older patients with distal cholangiocarcinoma (DC). Methods We compared 32 patients aged ≥ 75 years and 68 patients ag…
View article: Concomitant use of interleukin-2 and tacrolimus suppresses follicular helper T cell proportion and exerts therapeutic effect against lupus nephritis in systemic lupus erythematosus-like chronic graft versus host disease
Concomitant use of interleukin-2 and tacrolimus suppresses follicular helper T cell proportion and exerts therapeutic effect against lupus nephritis in systemic lupus erythematosus-like chronic graft versus host disease Open
Introduction Defective interleukin-2 (IL-2) production contributes to immune system imbalance in patients with systemic erythematosus lupus (SLE). Recent clinical studies suggested that low-dose IL-2 treatment is beneficial for SLE and the…
View article: Survey of hereditary angioedema episodes and quality of life impairment through a patient-participatory registry
Survey of hereditary angioedema episodes and quality of life impairment through a patient-participatory registry Open
Hereditary angioedema (HAE) adversely affects patients’ social and daily life significantly, and the disease burden is high. We recruited study participants from a patient-participatory registry, Rare and Undiagnosed Diseases Study (RUDY) …
View article: A Case of Distal Pancreatectomy after Distal Gastrectomy Preserving Remnant Stomach by Intraoperative Indocyanine Green Fluorography
A Case of Distal Pancreatectomy after Distal Gastrectomy Preserving Remnant Stomach by Intraoperative Indocyanine Green Fluorography Open
View article: A clinical case of enzootic bovine leukosis in a Holstein cow with minor clonality of B-cell in the peripheral blood
A clinical case of enzootic bovine leukosis in a Holstein cow with minor clonality of B-cell in the peripheral blood Open
A 4-year 9-month-old Holstein-Friesian dairy cow presented with anorexia. On physical examination, swelling of superficial lymph nodes, pelvic masses, and prolonged urination posture after urinating a small amount were noted. Hematological…
View article: Two-pore channel-2 and inositol trisphosphate receptors coordinate Ca2+ signals between lysosomes and the endoplasmic reticulum
Two-pore channel-2 and inositol trisphosphate receptors coordinate Ca2+ signals between lysosomes and the endoplasmic reticulum Open
View article: Exploring patient background and biomarkers associated with the development of dupilumab-associated conjunctivitis and blepharitis
Exploring patient background and biomarkers associated with the development of dupilumab-associated conjunctivitis and blepharitis Open
View article: Examination of nutritional indicators for elderly esophageal cancer
Examination of nutritional indicators for elderly esophageal cancer Open
View article: Analysis of serological immunonutritional indices and postoperative complications in rectal cancer
Analysis of serological immunonutritional indices and postoperative complications in rectal cancer Open