Tobias Reichlin
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View article: Characterization of sedation strategies in real-world use of pulsed field ablation Sub-analysis of the EU-PORIA registry
Characterization of sedation strategies in real-world use of pulsed field ablation Sub-analysis of the EU-PORIA registry Open
Background With the introduction of pulsed field ablation (PFA) to treat atrial fibrillation (AF), there is interest in studying workflow and sedation strategies to optimize integration into clinical practice. This sub-analysis characteriz…
View article: Adverse outcomes in patients with atrial fibrillation and a pacemaker: a cohort study
Adverse outcomes in patients with atrial fibrillation and a pacemaker: a cohort study Open
Aims Patients with atrial fibrillation (AF) are at a high risk of adverse cardiovascular outcomes. Little is known about the specific population of AF patients with implanted pacemaker (PM) and their prognosis. Therefore, we aimed to compa…
View article: Swiss national cardiac device registry: Changing trends in implantation procedures over the last two decades
Swiss national cardiac device registry: Changing trends in implantation procedures over the last two decades Open
There was a pronounced increase in the number of pacemaker procedures in Switzerland in the last two decades and a marked increase in ICD procedures, which have plateaued recently. Overall, there is a constant increase in mean age of patie…
View article: Safety and effectiveness of left atrial appendage occlusion in patients with atrial fibrillation and high bleeding risk: a cardinality-matched comparison with direct oral anticoagulation on long-term stroke and bleeding rates
Safety and effectiveness of left atrial appendage occlusion in patients with atrial fibrillation and high bleeding risk: a cardinality-matched comparison with direct oral anticoagulation on long-term stroke and bleeding rates Open
STUDY AIMS: Left atrial appendage occlusion (LAAO) is an accepted alternative stroke prevention strategy for patients with atrial fibrillation (AF) and contraindications to oral anticoagulation despite the lack of randomised data in this p…
View article: Inadvertent ventricular fibrillation induced by radiofrequency ablation with the lattice-tip catheter in proximity to implantable cardioverter-defibrillator leads
Inadvertent ventricular fibrillation induced by radiofrequency ablation with the lattice-tip catheter in proximity to implantable cardioverter-defibrillator leads Open
View article: Use of a large-area focal lattice-tip catheter for cavotricuspid isthmus ablation
Use of a large-area focal lattice-tip catheter for cavotricuspid isthmus ablation Open
View article: Beyond the learning curve: How operator experience affects pulsed-field ablation outcomes
Beyond the learning curve: How operator experience affects pulsed-field ablation outcomes Open
Although the learning curve for "single-shot" PFA is approximately 20 cases per operator based on procedure and fluoroscopy times, improvements in long-term PVI durability were observed after 60 cases. No difference in freedom from arrhyth…
View article: Impact of alternative efficacy end point definitions on reported outcomes after ablation of paroxysmal atrial fibrillation – Insights from the COMPARE-CRYO study using continuous rhythm monitoring
Impact of alternative efficacy end point definitions on reported outcomes after ablation of paroxysmal atrial fibrillation – Insights from the COMPARE-CRYO study using continuous rhythm monitoring Open
Alternative efficacy end point definitions have a significant impact on reported outcomes and health care utilization metrics after AF ablation. These findings are important when considering end point definitions other than the traditional…
View article: External Validation of the REACT‐HF Score for Predicting Heart Failure in Patients With Atrial Fibrillation
External Validation of the REACT‐HF Score for Predicting Heart Failure in Patients With Atrial Fibrillation Open
Background Validated risk prediction scores for incident heart failure (HF) in patients with atrial fibrillation are lacking. We aimed to externally validate the the HF prediction risk score derived from three large control randomized tria…
View article: Hemolysis Induced by Pulsed‐Field Ablation of Atrial Arrhythmias: A Comparative Analysis of Current Systems
Hemolysis Induced by Pulsed‐Field Ablation of Atrial Arrhythmias: A Comparative Analysis of Current Systems Open
Introduction Pulsed‐field ablation (PFA) is an emerging technology associated with dose‐dependent hemolysis as a recently recognized side effect. This study aimed to compare hemolysis levels and assess dose‐dependency across three PFA syst…
View article: Pulsed-field ablation vs. thermal ablation for paroxysmal atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials
Pulsed-field ablation vs. thermal ablation for paroxysmal atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials Open
View article: Biomarker panels for improved risk prediction and enhanced biological insights in patients with atrial fibrillation
Biomarker panels for improved risk prediction and enhanced biological insights in patients with atrial fibrillation Open
Atrial fibrillation (AF) increases the risk of adverse cardiovascular events, yet the underlying biological mechanisms remain unclear. We evaluate a panel of 12 circulating biomarkers representing diverse pathophysiological pathways in 381…
View article: Behavioural insights in the underuse of cardiac resynchronisation therapy in heart failure: a pilot survey on incentive perceptions among referring cardiologists.
Behavioural insights in the underuse of cardiac resynchronisation therapy in heart failure: a pilot survey on incentive perceptions among referring cardiologists. Open
These findings suggest that interventions drawing on behavioural economics, particularly those utilising social incentives and choice architecture redesign, may offer more effective to increasing CRT referrals than traditional incentives. …
View article: Colchicine in patients with aortic stenosis undergoing transcatheter aortic valve replacement: a double-blind randomized trial
Colchicine in patients with aortic stenosis undergoing transcatheter aortic valve replacement: a double-blind randomized trial Open
An inflammatory process may increase the risk of arrhythmias after transcatheter aortic valve replacement (TAVR). In this single-centre, double-blind, placebo-controlled, randomized trial we investigated the efficacy of colchicine to reduc…
View article: Safety and efficacy of a lattice-tip catheter for ventricular arrhythmia ablation: the AFFERA Ventricular Arrhythmia Ablation Registry (AVAAR)
Safety and efficacy of a lattice-tip catheter for ventricular arrhythmia ablation: the AFFERA Ventricular Arrhythmia Ablation Registry (AVAAR) Open
Aims The feasibility and safety of the lattice-tip catheter for ventricular arrhythmia (VA) ablation in humans remain largely unknown. This study aimed to assess feasibility, safety profile as well as patient outcomes after VA ablation wit…
View article: 72355 | Long-Term Continuous Rhythm Monitoring in Patients Undergoing Transcatheter Tricuspid Valve Replacement
72355 | Long-Term Continuous Rhythm Monitoring in Patients Undergoing Transcatheter Tricuspid Valve Replacement Open
View article: Voltage threshold adjustments for a novel pulsed-field ablation catheter with integrated mapping capabilities: lessons from a case series
Voltage threshold adjustments for a novel pulsed-field ablation catheter with integrated mapping capabilities: lessons from a case series Open
Background Accurate electroanatomical mapping relies on voltage thresholds to differentiate electrically inactive areas, fibrotic scar, and healthy myocardium. These thresholds have been well established for high-density mapping catheters …
View article: Discrimination of atrial fibrillation burden using clinical and cardiac imaging data
Discrimination of atrial fibrillation burden using clinical and cardiac imaging data Open
Background Current literature suggests that atrial fibrillation (AF) burden has prognostic implications in AF patients. However, it is not feasible to assess AF burden in all AF patients. Therefore, we aim to investigate whether clinical a…
View article: NT-proBNP as a predictor of successful pulmonary vein isolation using pulsed-field, cryoballoon or radiofrequency ablation
NT-proBNP as a predictor of successful pulmonary vein isolation using pulsed-field, cryoballoon or radiofrequency ablation Open
Background B-Type natriuretic peptide (NT-proBNP) is recognized as a biomarker for atrial disease as well as a predictor for the success of pulmonary vein isolation (PVI). In recent years pulsed-field ablation (PFA) has emerged as a novel …
View article: Comparison of hemolysis induced by different pulsed-field ablation systems
Comparison of hemolysis induced by different pulsed-field ablation systems Open
Background Pulsed-Field Ablation (PFA) is an innovative ablation technology, which, as a side effect, causes dose-dependent hemolysis. Currently, three PFA systems are commercially available in Europe: A pentaspline catheter, a lattice-tip…
View article: Characteristics of patients with isolated late recurrences after paroxysmal atrial fibrillation ablation - insights from the randomized COMPARE-CRYO study using continuous rhythm monitoring
Characteristics of patients with isolated late recurrences after paroxysmal atrial fibrillation ablation - insights from the randomized COMPARE-CRYO study using continuous rhythm monitoring Open
Background Early recurrences of atrial tachyarrythmias (ERAT) after pulmonary vein isolation (PVI) are common. While many correlate to subsequent late recurrences of atrial tachyarrhythmias (LRAT, definition: after the blanking period betw…
View article: Impact of left atrial anatomy on acute and long-term pulmonary vein isolation
Impact of left atrial anatomy on acute and long-term pulmonary vein isolation Open
Background The left atrial anatomy plays an important role in determining the success of balloon-based pulmonary vein isolation (PVI) for the treatment of atrial fibrillation (AF). The introduction of a second cryoballoon (CB) system neces…
View article: Adverse outcomes in patients with atrial fibrillation and a pacemaker: a cohort study
Adverse outcomes in patients with atrial fibrillation and a pacemaker: a cohort study Open
Background Patients with atrial fibrillation (AF) have a higher rate of pacemaker (PM) implantations compared to the general population. Little is known if a present PM in AF patients is associated with adverse cardiovascular outcomes. We …
View article: Biomarker and cognitive decline in atrial fibrillation: a prospective cohort study
Biomarker and cognitive decline in atrial fibrillation: a prospective cohort study Open
View article: Pulsed‐Field Ablation for Persistent Atrial Fibrillation in EU‐PORIA Registry
Pulsed‐Field Ablation for Persistent Atrial Fibrillation in EU‐PORIA Registry Open
Background Real‐life data on efficacy and safety of pulsed‐field ablation (PFA) using the pentaspline multi‐electrode catheter in symptomatic atrial fibrillation (AF) patients is still scarce. Objective This study aims to assess the effica…
View article: Long-Term Outcomes of Patients Requiring Pacemaker Implantation After Transcatheter Aortic Valve Replacement
Long-Term Outcomes of Patients Requiring Pacemaker Implantation After Transcatheter Aortic Valve Replacement Open
View article: The Association of Heart Failure and Liver T1 Mapping in Cardiac Magnetic Resonance Imaging
The Association of Heart Failure and Liver T1 Mapping in Cardiac Magnetic Resonance Imaging Open
Background/Objectives: The objective of this study was to investigate the association between congestive heart failure (CHF) and T1 mapping in both liver lobes using cardiac MRI. Methods: This retrospective study included patients who unde…
View article: Characterization of ventricular tachycardia ablation in end-stage heart failure patients with left ventricular assist device (CHANNELED registry)
Characterization of ventricular tachycardia ablation in end-stage heart failure patients with left ventricular assist device (CHANNELED registry) Open
Aims Patients with left ventricular assist devices (LVADs) are at high risk for ventricular tachycardia (VT), and data on VT ablation in patients with LVAD are scarce. This multicentre registry assessed the mechanism of VT, procedural para…
View article: Impact of the presence of sinus rhythm during cavotricuspid isthmus ablation for atrial flutter on the incidence of future new-onset atrial fibrillation: insights from an international multi-centre registry
Impact of the presence of sinus rhythm during cavotricuspid isthmus ablation for atrial flutter on the incidence of future new-onset atrial fibrillation: insights from an international multi-centre registry Open
View article: Dose-dependent ventricular lesion formation using a novel large-area pulsed field ablation catheter: A preclinical feasibility study
Dose-dependent ventricular lesion formation using a novel large-area pulsed field ablation catheter: A preclinical feasibility study Open
A novel large-area focal ablation catheter with the ability for 3D mapping and PFA was able to create dose-dependent deep ventricular lesions durable 1 week after ablation.