Reiko Watanabe
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View article: Series development of coaxial pulsed plasma thruster from 1 J to 8 J
Series development of coaxial pulsed plasma thruster from 1 J to 8 J Open
View article: Successful Treatment of Anemia With Ringed Sideroblasts Induced by Antidepressants Through Vitamin B6 Supplementation and Discontinuation of Antidepressants
Successful Treatment of Anemia With Ringed Sideroblasts Induced by Antidepressants Through Vitamin B6 Supplementation and Discontinuation of Antidepressants Open
Vitamin B6 (VB6) is a vital coenzyme for δ‐aminolevulinic acid synthase (ALAS) in heme biosynthesis. We report a 49‐year‐old male with severe microcytic anemia and ringed sideroblasts initially diagnosed as myelodysplastic syndrome (MDS). …
View article: Prognostic Value of Tertiary Lymphoid Structures in Epithelial Ovarian Carcinoma
Prognostic Value of Tertiary Lymphoid Structures in Epithelial Ovarian Carcinoma Open
Tertiary lymphoid structures (TLSs) have become the focus of antitumor immunity. However, the prognostic significance of TLSs in epithelial ovarian cancer (EOC) treated with primary debulking surgery (PDS) or interval debulking surgery (ID…
View article: Erythrodermic mycosis fungoides associated with Hodgkin lymphoma : A case report
Erythrodermic mycosis fungoides associated with Hodgkin lymphoma : A case report Open
View article: Pathologic method for extracting good prognosis group in triple‐negative breast cancer after neoadjuvant chemotherapy
Pathologic method for extracting good prognosis group in triple‐negative breast cancer after neoadjuvant chemotherapy Open
The area of residual tumor (ART) is a prognostic factor in patients treated with neoadjuvant chemotherapy (NAC) for lung, pancreatic, and rectal cancers. This study aimed to evaluate the usefulness of ART as a method for predicting the pro…
View article: Utility of a multidisciplinary team approach with transanal total mesorectal excision for resection of a large pelvic solitary fibrous tumor
Utility of a multidisciplinary team approach with transanal total mesorectal excision for resection of a large pelvic solitary fibrous tumor Open
Introduction Solitary fibrous tumors require complete surgical resection to avoid recurrence. Large solitary fibrous pelvic tumors are difficult to resect completely with conventional surgical methods. We herein report a case in which a jo…
View article: Changes in Central Venous Catheter Use in the Hematology Unit with the Introduction of Ultrasound Guidance and a Peripherally Inserted Central Venous Catheter
Changes in Central Venous Catheter Use in the Hematology Unit with the Introduction of Ultrasound Guidance and a Peripherally Inserted Central Venous Catheter Open
Objective A central venous catheter (CVC) is often needed to treat hematologic diseases, but it is accompanied by many complications. Ultrasound guidance (USG) or a peripherally inserted central venous catheter (PICC) can reduce such compl…
View article: Novel Indicators of Transplant Outcomes for PhALL: Current Molecular-Relapse-Free Survival
Novel Indicators of Transplant Outcomes for PhALL: Current Molecular-Relapse-Free Survival Open
Molecular relapse after allogeneic hematopoietic cell transplantation (allo-HCT) has been thought to predict clinical relapse in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (PhALL). Tyrosine kinase inhibitor…
View article: Prognostic impact of peripheral blood neutrophil to lymphocyte ratio in advanced-stage pulmonary large cell neuroendocrine carcinoma and its association with the immune-related tumour microenvironment
Prognostic impact of peripheral blood neutrophil to lymphocyte ratio in advanced-stage pulmonary large cell neuroendocrine carcinoma and its association with the immune-related tumour microenvironment Open
View article: Efficacy of physical exercise using the balance board game on physical and psychological function in patients with hematological malignancies confined to a bioclean room
Efficacy of physical exercise using the balance board game on physical and psychological function in patients with hematological malignancies confined to a bioclean room Open
Improvements in physical function were clearly observed following the use of Wii PT in patients confined to a bioclean room. However, compared to Therapist PT, Wii PT was less effective in improving the psychological function of patients.
View article: Rice bran protein ameliorates diabetes, reduces fatty liver, and has renoprotective effects in Zucker Diabetic Fatty rats
Rice bran protein ameliorates diabetes, reduces fatty liver, and has renoprotective effects in Zucker Diabetic Fatty rats Open
The beneficial effects of rice bran protein (RBP), which comprises 12.8% of rice bran, have not been fully characterized. Therefore, the effects of RBP on diabetes, fatty liver, and diabetic nephropathy were investigated in Zucker Diabetic…
View article: Clinical status and prognostic factors in Japanese patients with uterine leiomyosarcoma
Clinical status and prognostic factors in Japanese patients with uterine leiomyosarcoma Open
Despite complete removal of the primary lesion, the clinical course of patients with uLMS was poor due to recurrence of distant metastasis. The application of a suitable biomarker and effective adjuvant chemotherapy are required to improve…
View article: Outcomes and Prognostic Factors for Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia Who Underwent Allogeneic Hematopoietic Cell Transplantation: A KSGCT Multicenter Analysis
Outcomes and Prognostic Factors for Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia Who Underwent Allogeneic Hematopoietic Cell Transplantation: A KSGCT Multicenter Analysis Open
A multicenter retrospective study was performed to evaluate the prognostic factors in 104 patients with relapsed or refractory acute lymphoblastic leukemia (ALL), who underwent allogeneic hematopoietic cell transplantation (HCT) between 20…
View article: Allogeneic hematopoietic stem cell transplantation for aplastic anemia with pre‐transplant conditioning using fludarabine, reduced‐dose cyclophosphamide, and low‐dose thymoglobulin: A KSGCT prospective study
Allogeneic hematopoietic stem cell transplantation for aplastic anemia with pre‐transplant conditioning using fludarabine, reduced‐dose cyclophosphamide, and low‐dose thymoglobulin: A KSGCT prospective study Open
The optimal pre‐transplant conditioning for aplastic anemia (AA) remains unclear. We performed a prospective study on allogeneic transplantation from a related or unrelated donor for adult patients with AA. We assessed whether reduced‐dose…
View article: Higher estimated net endogenous acid production with lower intake of fruits and vegetables based on a dietary survey is associated with the progression of chronic kidney disease
Higher estimated net endogenous acid production with lower intake of fruits and vegetables based on a dietary survey is associated with the progression of chronic kidney disease Open
View article: Physiological Multifunctions of Rice Proteins of Endosperm and Bran
Physiological Multifunctions of Rice Proteins of Endosperm and Bran Open
Although it is considered a staple food, rice intake is under serious debate for its physiological usefulness, especially for diabetic patients, because of starch content. However, rice protein, the second major component of rice, has gain…
View article: A Prospective, Longitudinal Observation of the Incidence, Treatment, and Survival of Late Acute and Chronic Graft-versus-Host Disease by National Institutes of Health Criteria in a Japanese Cohort
A Prospective, Longitudinal Observation of the Incidence, Treatment, and Survival of Late Acute and Chronic Graft-versus-Host Disease by National Institutes of Health Criteria in a Japanese Cohort Open
To prospectively validate the incidence, manifestations, and outcomes of graft-versus-host disease (GVHD) by National Institutes of Health criteria, we recruited 406 hematopoietic stem cell transplantation recipients at 16 transplant cente…
View article: PF407 TREATMENT‐FREE REMISSION IN PATIENTS WITH CHRONIC MYELOGENOUS LEUKEMIA FOLLOWING FIRST‐LINE DASATINIB, 1ST DADI/IMIDAS4
PF407 TREATMENT‐FREE REMISSION IN PATIENTS WITH CHRONIC MYELOGENOUS LEUKEMIA FOLLOWING FIRST‐LINE DASATINIB, 1ST DADI/IMIDAS4 Open
Background: The main treatment goal for patients with chronic phase chronic myelogenous leukemia (CML‐CP) is discontinuation of tyrosine kinase inhibitor (TKI) therapy. In the previous DAsatinib Discontinuation (DADI) trial, we showed that…
View article: Feasibility and utility of a panel testing for 114 cancer‐associated genes in a clinical setting: A hospital‐based study
Feasibility and utility of a panel testing for 114 cancer‐associated genes in a clinical setting: A hospital‐based study Open
Next‐generation sequencing ( NGS ) of tumor tissue (ie, clinical sequencing) can guide clinical management by providing information about actionable gene aberrations that have diagnostic and therapeutic significance. Here, we undertook a h…
View article: Pretreatment evaluation of fluorescence resonance energy transfer‐based drug sensitivity test for patients with chronic myelogenous leukemia treated with dasatinib
Pretreatment evaluation of fluorescence resonance energy transfer‐based drug sensitivity test for patients with chronic myelogenous leukemia treated with dasatinib Open
Tyrosine kinase inhibitors ( TKI ) are used for primary therapy in patients with newly diagnosed CML . However, a reliable method for optimal selection of a TKI from the viewpoint of drug sensitivity of CML cells has not been established. …
View article: Prognostic relevance of genetic alterations in diffuse lower-grade gliomas
Prognostic relevance of genetic alterations in diffuse lower-grade gliomas Open
BACKGROUND: Diffuse lower-grade gliomas (LGGs) are genetically classified into 3 distinct subtypes based on isocitrate dehydrogenase (IDH) mutation status and codeletion of chromosome 1p and 19q (1p/19q). However, the subtype-specific effe…
View article: The aggressive clinical courses of Hodgkin lymphoma primarily diagnosed as methotrexate-induced non-specific lymphoproliferative disorder in patients with rheumatoid arthritis
The aggressive clinical courses of Hodgkin lymphoma primarily diagnosed as methotrexate-induced non-specific lymphoproliferative disorder in patients with rheumatoid arthritis Open
Recently, attention has been focused on methotrexate-induced lymphoproliferative disease (MTX-LPD), and atypical phenotypes are occasionally documented. We encountered two patients with rheumatoid arthritis (RA) who were diagnosed with non…
View article: The Role Recognition of Assistant Head Nurses and Their Thoughts Upon Assuming Their Posts
The Role Recognition of Assistant Head Nurses and Their Thoughts Upon Assuming Their Posts Open
目 的：本研究の目的は, 副看護師長が新規着任時に抱いた思いと, 自身の役割認識を明らかにすること. 方 法：新任副看護師長37名を対象に, 「任に就いての思い」「今時点で認識している副看護師長の役割」「現在の課題」について自記式質問紙にて調査を行った. 結 果：着任時の思いとして,【担うことへの煩悶】【自身に必要とされる力への思案】【自身の評価に対する心配】【着任への抵抗】【昇格への意気込み】の5カテゴリーが, 着任した時点で認識している役割についても,【師長との連携】【…
View article: Rice endosperm protein slows progression of fatty liver and diabetic nephropathy in Zucker diabetic fatty rats
Rice endosperm protein slows progression of fatty liver and diabetic nephropathy in Zucker diabetic fatty rats Open
We previously reported that rice endosperm protein (REP) has renoprotective effects in Goto–Kakizaki rats, a non-obese diabetic model. However, whether these effects occur in obese diabetes remains unclear. This study aimed to clarify the …
View article: Endometrial Cancer Occurring 27 Years after Radiation Therapy for Cervical Carcinoma
Endometrial Cancer Occurring 27 Years after Radiation Therapy for Cervical Carcinoma Open
View article: Comparative Effectiveness of Blonanserin and Paliperidone in 93 In-patients with Acute- to Maintenance-phase Schizophrenia
Comparative Effectiveness of Blonanserin and Paliperidone in 93 In-patients with Acute- to Maintenance-phase Schizophrenia Open
When initiating treatment for acute-phase schizophrenia, careful consideration needs to be given to which drug will be used in the subsequent maintenance phase. Since blonanserin (BNS) and paliperidone (PAL) are both first-line treatments …
View article: A case report of diffuse large B-cell lymphoma, spindle cell variant
A case report of diffuse large B-cell lymphoma, spindle cell variant Open
背景 : びまん性大細胞型 B 細胞リンパ腫 (diffuse large B-cell lymphoma ; DLBCL) のまれな細胞形態である紡錘形細胞亜型 (spindle cell variant ; Sp) を経験したので報告する.
View article: Therapeutic approach for primary plasma cell leukemia: case reports and a review of the literature
Therapeutic approach for primary plasma cell leukemia: case reports and a review of the literature Open
View article: Effect of the order of TBI and cyclophosphamide administration on the outcome of allogeneic hematopoietic stem cell transplantation
Effect of the order of TBI and cyclophosphamide administration on the outcome of allogeneic hematopoietic stem cell transplantation Open
View article: <scp>TM</scp>‐233, a novel analog of 1′‐acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both <scp>JAK</scp>/<scp>STAT</scp> and proteasome activities
<span>TM</span>‐233, a novel analog of 1′‐acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both <span>JAK</span>/<span>STAT</span> and proteasome activities Open
Although the introduction of bortezomib and immunomodulatory drugs has led to improved outcomes in patients with multiple myeloma, the disease remains incurable. In an effort to identify more potent and well‐tolerated agents for myeloma, w…