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View article: Feasibility and diagnostic yield of a photoplethysmography-based arrhythmia screening and integrated management pathway in a COPD outpatient clinic
Feasibility and diagnostic yield of a photoplethysmography-based arrhythmia screening and integrated management pathway in a COPD outpatient clinic Open
Background and aims Guidelines recommend opportunistic atrial fibrillation (AF) screening in high-risk populations, including COPD patients. This cohort study aimed to evaluate the feasibility and yield of a photoplethysmography (PPG)-base…
Associated factors of fatigue in patients with COPD: results from the FAntasTIGUE study Open
Background Fatigue is present in about half of the patients with COPD. The associated factors of fatigue in COPD remain unclear and have not been studied in an integrated and holistic analysis. The aim of this study is to identify associat…
The impact of bronchoscopic lung volume reduction with endobronchial valves with or without pulmonary rehabilitation on symptoms of fatigue, anxiety and depression: a multicentre randomised controlled trial Open
Background Bronchoscopic lung volume reduction using one-way endobronchial valves (BLVR-EBV) improves exercise capacity and quality of life in patients with severe emphysema. However, its effect on symptoms of fatigue, anxiety and depressi…
Successful treatment of a persistent air leak with an endobronchial valve in a 17‐year‐old patient with necrotizing pneumonia Open
Pleural empyema is a severe condition associated with high morbidity and mortality. Treatment usually consists of pleural drainage with chest tube or surgery, in combination with antimicrobial treatment. Severe pneumonia can evolve in a ne…
Systemic pro-inflammatory response following bronchoscopic lung volume reduction using endobronchial valves Open
Rationale Bronchoscopic lung volume reduction treatment using endobronchial valves (EBV) is an effective treatment for severe COPD patients by improving lung function and quality of life. However, little is known about its effects on syste…
Lung Hyperinflation as Treatable Trait in Chronic Obstructive Pulmonary Disease: A Narrative Review Open
Lung hyperinflation (LH) is a common clinical feature in patients with chronic obstructive pulmonary disease (COPD). It results from a combination of reduced elastic lung recoil as a consequence of irreversible destruction of lung parenchy…
Impact and timing of pulmonary rehabilitation in patients undergoing bronchoscopic lung volume reduction with endobronchial valves: A multicentre randomized controlled trial in patients with severe emphysema Open
Background and Objective Both bronchoscopic lung volume reduction with endobronchial valves (BLVR‐EBV) and pulmonary rehabilitation (PR) are effective treatments for improving exercise capacity and patient‐reported outcomes in patients wit…
Feasibility and diagnostic yield of a photoplethysmography-based arrhythmia screening and integrated management pathway in a chronic obstructive pulmonary disease outpatient clinic Open
Background Guidelines recommend opportunistic screening for atrial fibrillation (AF) in high-risk populations, including chronic obstructive pulmonary disease (COPD) patients. Purpose We aimed to assess the feasibility and yield of a photo…
Pulmonary function trajectories in COVID-19 survivors with- and without pre-existing respiratory disease at three and twelve months after hospital discharge Open
A significant proportion of COVID-19 survivors still experience a reduced diffusion capacity three and twelve months after discharge. We aimed to compare pulmonary function trajectories between hospitalized COVID-19 patients with pre-exist…
Differential Response to 12 Weeks of Once-Daily Tiotropium/Olodaterol Fixed Dose Combination in Patients with COPD: A Multidimensional Response Profiling in the TORRACTO Study Open
Individual responses on endurance time and pulmonary function after 12 weeks of T/O are heterogeneous. This study identified clusters in COPD patients with markedly different multidimensional response on LABD.
View article: High-Resolution Computed Tomography-approximated Perfusion Is Comparable to Nuclear Perfusion Imaging in Severe Chronic Obstructive Pulmonary Disease
High-Resolution Computed Tomography-approximated Perfusion Is Comparable to Nuclear Perfusion Imaging in Severe Chronic Obstructive Pulmonary Disease Open
"HRCT-Approximated Perfusion is Comparable to Nuclear Perfusion Imaging in Severe COPD." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp.
Impact of Coronavirus Disease 2019-Related Infection Prevention and Control Measures on the Occurrence of COPD Exacerbations During Inpatient Pulmonary Rehabilitation Open
COVID-19-related IPC measures did not significantly reduce the AECOPD rate during inpatient PR in a single-center setting. The current findings suggest that avoidance of health care may be an important factor in the observed reduction of A…
View article: The Impact of Long COVID-19 on Mental Health: Observational 6-Month Follow-Up Study
The Impact of Long COVID-19 on Mental Health: Observational 6-Month Follow-Up Study Open
Background The psychological impact of COVID-19 can be substantial. However, knowledge about long-term psychological outcomes in patients with COVID-19 is scarce. Objective In this longitudinal, observational study, we aimed to reveal symp…
Implementation of Bronchoscopic Lung Volume Reduction Using One-Way Endobronchial Valves: A Retrospective Single-Centre Cohort Study Open
Background: Bronchoscopic lung volume reduction (BLVR) using 1-way endobronchial valves (EBV) has become a guideline treatment in patients with advanced emphysema. Evidence from this minimally invasive treatment derives mainly from well-de…
View article: The Impact of Long COVID-19 on Mental Health: Observational 6-Month Follow-Up Study (Preprint)
The Impact of Long COVID-19 on Mental Health: Observational 6-Month Follow-Up Study (Preprint) Open
BACKGROUND The psychological impact of COVID-19 can be substantial. However, knowledge about long-term psychological outcomes in patients with COVID-19 is scarce. OBJECTIVE In this longitudinal, observational study, we aimed to reveal s…
View article: Severe Fatigue in Long COVID: Web-Based Quantitative Follow-up Study in Members of Online Long COVID Support Groups
Severe Fatigue in Long COVID: Web-Based Quantitative Follow-up Study in Members of Online Long COVID Support Groups Open
Background Fatigue is the most commonly reported symptom in patients with persistent complaints following COVID-19 (ie, long COVID). Longitudinal studies examining the intensity of fatigue and differentiating between physical and mental fa…
Functional Outcomes and Their Association With Physical Performance in Mechanically Ventilated Coronavirus Disease 2019 Survivors at 3 Months Following Hospital Discharge: A Cohort Study Open
OBJECTIVES: We performed a comprehensive health assessment in mechanically ventilated coronavirus disease 2019 survivors to assess the impact of respiratory and skeletal muscle injury sustained during ICU stay on physical performance at 3 …
View article: Recovery from COVID-19: a sprint or marathon? 6-month follow-up data from online long COVID-19 support group members
Recovery from COVID-19: a sprint or marathon? 6-month follow-up data from online long COVID-19 support group members Open
Background It remains unknown whether and to what extent members of online “long COVID” peer support groups remain symptomatic and limited over time. Therefore, we aimed to evaluate symptoms in members of online long COVID peer support gro…
View article: A multicentre cluster-randomized clinical trial to improve antibiotic use and reduce length of stay in hospitals: comparison of three measurement and feedback methods
A multicentre cluster-randomized clinical trial to improve antibiotic use and reduce length of stay in hospitals: comparison of three measurement and feedback methods Open
Background Various metrics of hospital antibiotic use might assist in guiding antimicrobial stewardship (AMS). Objectives To compare patient outcomes in association with three methods to measure and feedback information on hospital antibio…
Dual-Energy Computed Tomography Compared to Lung Perfusion Scintigraphy to Assess Pulmonary Perfusion in Patients Screened for Endoscopic Lung Volume Reduction Open
Background: Endoscopic lung volume reduction (ELVR) using one-way endobronchial valves is a technique to reduce hyperinflation in patients with severe emphysema by inducing collapse of a severely destroyed pulmonary lobe. Patient selection…
View article: Understanding and Being Understood: Information and Care Needs of 2113 Patients With Confirmed or Suspected COVID-19
Understanding and Being Understood: Information and Care Needs of 2113 Patients With Confirmed or Suspected COVID-19 Open
To become a proactive and informed partner in postacute coronavirus disease 2019 (COVID-19) management, patients need to have the knowledge, skills, and confidence to self-manage COVID-19-related health challenges. Due to several restricti…
View article: Generic and Respiratory-Specific Quality of Life in Non-Hospitalized Patients with COVID-19
Generic and Respiratory-Specific Quality of Life in Non-Hospitalized Patients with COVID-19 Open
The impact of coronavirus disease 2019 (COVID-19) on quality of life appears to be highly underestimated, especially in patients who have not been admitted to the hospital. Therefore, our aim was to assess respiratory-specific quality of l…
View article: Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome?
Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome? Open
Background Many patients with COVID-19 did not require hospitalisation, nor underwent COVID-19 testing. There is anecdotal evidence that patients with “mild” COVID-19 may complain about persistent symptoms, even weeks after the infection. …