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Tobacco smoking is associated with combined pulmonary fibrosis and emphysema and worse outcomes in interstitial lung disease Open

Dylan Douglas, L. Keating, R. Strykowski, Cathryn T. Lee, Nicole Garcia , et al. · 2023

Smoking in ILD is associated with combined pulmonary fibrosis and emphysema and worse clinical outcomes.

Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts Open

Ayodeji Adegunsoye, Chad A. Newton, Justin M. Oldham, Brett Ley, Cathryn T. Lee , et al. · 2023

Pulmonary fibrosis (PF) is characterized by profound scarring and poor survival. We investigated the association of leukocyte telomere length (LTL) with chronological age and mortality across racially diverse PF cohorts. LTL measurements a…

Evaluation of Pulmonary Fibrosis Outcomes by Race and Ethnicity in US Adults Open

Ayodeji Adegunsoye, Elizabeth Freiheit, Emily White, Bhavika Kaul, Chad A. Newton , et al. · 2023

Importance Pulmonary fibrosis (PF) is characterized by progressive scarring of lung tissue and poor survival. Racial and ethnic minority populations face the greatest risk of morbidity and mortality from disparities impacting respiratory h…

Sex- and Race-Based Differences in the Treatment of Interstitial Lung Diseases in North America and Australasia Open

Deborah Assayag, Ayodeji Adegunsoye, Robert Sheehy, Julie Morisset, Nasreen Khalil , et al. · 2023

Mortality Risk From COVID-19 Among Unvaccinated Subjects With Autoimmune Phenotypes of Interstitial Lung Disease Open

Rachel K Strykowski, Maria Poonawalla, Albina Tyker, Iazsmin Bauer Ventura, Cathryn Lee , et al. · 2022

Interstitial Lung Disease in Firefighters: An Emerging Occupational Hazard Open

Cathryn T. Lee, Iazsmin Bauer Ventura, Emily Phillips, A. Leahy, Renea Jablonski , et al. · 2022

Introduction Occupational risk factors for interstitial lung disease (ILD) are a remediable aspect of this progressive pulmonary disorder. The association between firefighting and ILD is unknown. Our objective was to assess the characteris…

High-titer rheumatoid factor seropositivity predicts mediastinal lymphadenopathy and mortality in rheumatoid arthritis-related interstitial lung disease Open

Albina Tyker, Iazsmin Bauer Ventura, Cathryn T. Lee, R. Strykowski, Nicole Garcia , et al. · 2021

Mortality Risk from COVID-19 among Unvaccinated Subjects with Autoimmune Phenotypes of Interstitial Lung Disease Open

R. Strykowski, Maria Poonawalla, Albina Tyker, Iazsmin Bauer Ventura, Cathryn Lee , et al. · 2021

Background: The impact of the SARS-CoV-2 virus on patients with interstitial lung disease (ILD) remains poorly understood. As patients with ILD often have severe underlying lung parenchymal involvement, and immunosuppressive therapy is com…

MORPHOLOGICAL INDICES ASSOCIATED WITH PULMONARY HYPERTENSION AND MORTALITY PREDICTION IN INTERSTITIAL LUNG DISEASE Open

R. Boente, Kavitha Selvan, LINDA BOCANEGRA-ENGLISH, John Donatelli, Danielle Stahlbaum , et al. · 2021

Association of antinuclear antibody seropositivity with inhaled environmental exposures in patients with interstitial lung disease Open

Kathleen Biblowitz, Cathryn Lee, Daisy Zhu, Imre Noth, Rekha Vij , et al. · 2021

Background Interstitial lung diseases (ILDs) are diffuse parenchymal lung disorders that cause substantial morbidity and mortality. In patients with ILD, elevated antinuclear antibody (ANA) titres may be a sign of an autoimmune process. In…

Differentiation of Idiopathic Pulmonary Fibrosis from Connective Tissue Disease-Related Interstitial Lung Disease Using Quantitative Imaging Open

Jonathan H. Chung, Ayodeji Adegunsoye, Brenna Cannon, Rekha Vij, Justin M. Oldham , et al. · 2021

A usual interstitial pneumonia (UIP) imaging pattern can be seen in both idiopathic pulmonary fibrosis (IPF) and connective tissue disease-related interstitial lung disease (CTD-ILD). The purpose of this multicenter study was to assess whe…

Correction to: Vessel-related structures predict UIP pathology in those with a non-IPF pattern on CT Open

Jonathan H. Chung, Ayodeji Adegunsoye, Justin M. Oldham, Rekha Vij, Aliya N. Husain , et al. · 2021

High-Titer Rheumatoid Factor Seropositivity Predicts Mediastinal Lymphadenopathy and Mortality Risk in Rheumatoid Arthritis-Interstitial Lung Disease Open

Albina Tyker, Iazsmin Bauer Ventura, Charles Oshinsky, C.T. Lee, R. Strykowski , et al. · 2021

The MUC5B rs35705950 Allele Associates with Increased Honeycombing Risk in Individuals of Diverse Ancestry with Pulmonary Fibrosis Open

Ayodeji Adegunsoye, Nicole Garcia, A. Tyker, C.T. Lee, R. Strykowski , et al. · 2021

Background:Radiologic honeycombing (HC), a form of pulmonary fibrosis (PF), is common in interstitial lung disease (ILD), has a devastating effect on survival, and is strongly associated with the gain-of-function MUC5B promoter polymorphis…

Hypothyroidism Is Prevalent Across the Pulmonary Fibrosis Spectrum Independent of Radiologic Honeycombing Open

Nicole Garcia, Albina Tyker, C.T. Lee, R. Strykowski, Iazsmin Bauer Ventura , et al. · 2021

Blood Transcriptomics Predicts Progression of Pulmonary Fibrosis and Associated Natural Killer Cells Open

Yong Huang, Justin M. Oldham, Shwu‐Fan Ma, Avraham Unterman, Shu-Yi Liao , et al. · 2021

Rationale: Disease activity in idiopathic pulmonary fibrosis (IPF) remains highly variable, poorly understood, and difficult to predict. Objectives: To identify a predictor using short-term longitudinal changes in gene expres…

Characteristics and Prevalence of Domestic and Occupational Inhalational Exposures Across Interstitial Lung Diseases Open

Cathryn T. Lee, Ayodeji Adegunsoye, Jonathan H. Chung, Iazsmin Bauer Ventura, Renea Jablonski , et al. · 2021

Automated CT Analysis of Major Forms of Interstitial Lung Disease Open

Marlee S. Crews, Brian J. Bartholmai, Ayodeji Adegunsoye, Justin M. Oldham, Steven M. Montner , et al. · 2020

This study aimed to determine diagnostic and prognostic differences in major forms of interstitial lung disease using quantitative CT imaging. A retrospective study of 225 subjects with a multidisciplinary diagnosis of idiopathic pulmonary…

Telomere biology disorder prevalence and phenotypes in adults with familial hematologic and/or pulmonary presentations Open

Simone Feurstein, Ayodeji Adegunsoye, Danijela Mojsilovic, Rekha Vij, Allison DePersia , et al. · 2020

Telomere biology disorders (TBDs) present heterogeneously, ranging from infantile bone marrow failure associated with very short telomeres to adult-onset interstitial lung disease (ILD) with normal telomere length. Yield of genetic testing…

CPAP Adherence, Mortality, and Progression-Free Survival in Interstitial Lung Disease and OSA Open

Ayodeji Adegunsoye, Julie M. Neborak, Daisy Zhu, Benjamin Cantrill, Nicole Garcia , et al. · 2020

Specialty Pharmacy Role in a Pulmonary Fibrosis Clinic at a Large Academic Medical Center Open

Shannon M. Rotolo, L.K. Flowers, Angela Leahy, M.E. Strek, Rekha Vij , et al. · 2020

Impact of a Historical Asthma Diagnosis on Pulmonary Function of Patients with Interstitial Lung Disease Open

Alexandra Weiss, C. Klyman, C. Lee, Iazsmin Bauer Ventura, Jonathan H. Chung , et al. · 2020

Interstitial Lung Disease and Inhalational Exposures: Demographic, Clinical, and Radiologic Characteristics Open

C. Lee, Ayodeji Adegunsoye, Jonathan H. Chung, Alexandra Weiss, Renea Jablonski , et al. · 2020

Firefighters with Interstitial Lung Disease: An Emerging Occupational Exposure Open

C. Lee, Emily Phillips, Renea Jablonski, A. Leahy, Steven M. Montner , et al. · 2020

005. COMPARATIVE EVALUATION OF RADIOGRAPHIC AND AUTOIMMUNE SEROLOGIC FEATURES BETWEEN ANCA- ASSOCIATED ILD AND IPAF Open

Iazsmin Bauer Ventura, Ayodeji Adegunsoye, Mary E. Strek, Jonathan H. Chung, Rekha Vij , et al. · 2019

Integrating Genomics Into Management of Fibrotic Interstitial Lung Disease Open

Ayodeji Adegunsoye, Rekha Vij, Imre Noth · 2019

Computed Tomography Honeycombing Identifies a Progressive Fibrotic Phenotype with Increased Mortality across Diverse Interstitial Lung Diseases Open

Ayodeji Adegunsoye, Justin M. Oldham, Shashi Bellam, Steven M. Montner, Matthew M. Churpek , et al. · 2019

Rationale: Honeycombing on chest computed tomography (CT) has been described in diverse forms of interstitial lung disease (ILD); however, its prevalence and association with mortality across the spectrum of ILD remains unclear. …

View article: T cell Co-Stimulatory molecules ICOS and CD28 stratify idiopathic pulmonary fibrosis survival

T cell Co-Stimulatory molecules ICOS and CD28 stratify idiopathic pulmonary fibrosis survival Open

Catherine A. Bonham, Cara L. Hrusch, Kelly Blaine, Stephenie T. Manns, Rekha Vij , et al. · 2019

Idiopathic pulmonary fibrosis (IPF) is a devastating disease that kills as many Americans as breast cancer each year. This study investigated whether lung function decline and survival associates with adaptive immunity in patients with IPF…

View article: Anti-RNA binding protein positivity in idiopathic interstitial pneumonia

Anti-RNA binding protein positivity in idiopathic interstitial pneumonia Open

Rene S. Bermea, Ayodeji Adegunsoye, Justin M. Oldham, Iazsmin Bauer Ventura, Cathryn Lee , et al. · 2018

View article: African-American race and mortality in interstitial lung disease: a multicentre propensity-matched analysis

African-American race and mortality in interstitial lung disease: a multicentre propensity-matched analysis Open

Ayodeji Adegunsoye, Justin M. Oldham, Shashi Bellam, Jonathan H. Chung, Paul A. Chung , et al. · 2018

We studied whether African-American race is associated with younger age and decreased survival time at diagnosis of interstitial lung disease (ILD). We performed a multicentre, propensity score-matched analysis of patients with an ILD diag…