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View article: PPNet: Identifying Functional Association Networks by Phylogenetic Profiling of Prokaryotic Genomes
PPNet: Identifying Functional Association Networks by Phylogenetic Profiling of Prokaryotic Genomes Open
This study developed PPNet, the first tool that can be used to infer large-scale bacterial functional association networks of a single species. PPNet includes a method for assigning the uniqueness of a bacterial strain using the average nu…
View article: Pathogenicity and Molecular Typing of Fowl Adenovirus-Associated With Hepatitis/Hydropericardium Syndrome in Central China (2015–2018)
Pathogenicity and Molecular Typing of Fowl Adenovirus-Associated With Hepatitis/Hydropericardium Syndrome in Central China (2015–2018) Open
In central China, a large number of broiler and layer flocks have suffered from outbreaks of severe hepatitis/hydropericardium syndrome (HHS). This resulted in huge economic losses to the poultry industry, from 2015 to 2018. To identify th…
View article: Identification of an Integrase That Responsible for Precise Integration and Excision of Riemerella anatipestifer Genomic Island
Identification of an Integrase That Responsible for Precise Integration and Excision of Riemerella anatipestifer Genomic Island Open
Riemerella anatipestifer is a Gram-negative, pathogenic bacterium, which is harmful to poultry. However, the genomic islands (GIs) in R. anatipestifer are not well-studied. In this study, a 10K genomic island was predicted by the bioinform…
View article: The Impact of<i>Lactobacillus plantarum</i>on the Gut Microbiota of Mice with DSS-Induced Colitis
The Impact of<i>Lactobacillus plantarum</i>on the Gut Microbiota of Mice with DSS-Induced Colitis Open
The pathogenesis of inflammatory bowel disease (IBD) is due in part to a loss of equilibrium among the gut microbiota, epithelial cells, and resident immune cells. The gut microbiota contains a large proportion of probiotic commensal Lacto…
View article: Deletion of the <i>Riemerella anatipestifer</i> type IX secretion system gene <i>sprA</i> results in differential expression of outer membrane proteins and virulence
Deletion of the <i>Riemerella anatipestifer</i> type IX secretion system gene <i>sprA</i> results in differential expression of outer membrane proteins and virulence Open
Riemerella anatipestifer (RA), the causative agent of infectious serositis that targets ducklings and other poultry, secretes protein via the type IX secretion system (T9SS). The proteins transported by T9SS are located on the bacterial ce…
View article: Identification and comparative profiling of gonadal microRNAs in the adult pigeon (<i>Columba livia</i>)
Identification and comparative profiling of gonadal microRNAs in the adult pigeon (<i>Columba livia</i>) Open
1. MicroRNAs are small noncoding RNA molecules that play crucial roles in gene expression. However, the comparative profiling of testicular and ovarian microRNAs in birds are rarely reported, particularly in pigeon. 2. In this study, Illum…
View article: Haemophilus parasuis Infection Disrupts Adherens Junctions and Initializes EMT Dependent on Canonical Wnt/β-Catenin Signaling Pathway
Haemophilus parasuis Infection Disrupts Adherens Junctions and Initializes EMT Dependent on Canonical Wnt/β-Catenin Signaling Pathway Open
In this study, animal experimentation verified that the canonical Wnt/β-catenin signaling pathway was activated under a reduced activity of p-β-catenin (Ser33/37/Thr41) and an increased accumulation of β-catenin in the lungs and kidneys of…
View article: Riemerella anatipestifer Type IX Secretion System Is Required for Virulence and Gelatinase Secretion
Riemerella anatipestifer Type IX Secretion System Is Required for Virulence and Gelatinase Secretion Open
Riemerella anatipestifer (RA), a major causative agent of septicemia anserum exsudativa in domesticated ducklings, has a protein secretion system known as the type IX secretion system (T9SS). It is unknown whether the T9SS contributes to t…
View article: The Role of the Regulator Fur in Gene Regulation and Virulence of Riemerella anatipestifer Assessed Using an Unmarked Gene Deletion System
The Role of the Regulator Fur in Gene Regulation and Virulence of Riemerella anatipestifer Assessed Using an Unmarked Gene Deletion System Open
Riemerella anatipestifer, an avian pathogen, has resulted in enormous economic losses to the duck industry globally. Notwithstanding, little is known regarding the physiological, pathogenic and virulence mechanisms of Riemerella anatipesti…
View article: A meta-analysis of transcriptomic characterization revealed extracellular matrix pathway involved in the H5N1 and H7N9 infections
A meta-analysis of transcriptomic characterization revealed extracellular matrix pathway involved in the H5N1 and H7N9 infections Open
Avian-origin H5N1 and H7N9 influenza A viruses are capable of causing lethal infection in humans, with serious lung pathology and leading to acute respiratory distress syndrome. The contribution of host response associated with the poor pr…
View article: A Novel RAYM_RS09735/RAYM_RS09740 Two-Component Signaling System Regulates Gene Expression and Virulence in Riemerella anatipestifer
A Novel RAYM_RS09735/RAYM_RS09740 Two-Component Signaling System Regulates Gene Expression and Virulence in Riemerella anatipestifer Open
The Gram-negative bacterium Riemerella anatipestifer is an important waterfowl pathogen, causing major economic losses to the duck-producing industry. However, little is known of the virulence factors that mediate pathogenesis during R. an…
View article: Probiotic mixture ameliorates heat stress of laying hens by enhancing intestinal barrier function and improving gut microbiota
Probiotic mixture ameliorates heat stress of laying hens by enhancing intestinal barrier function and improving gut microbiota Open
Heat stress (HS) is a major stressor for laying hens. It causes enormous financial losses worldwide annually. The purpose of this study was to investigate the effect and mechanism of a probiotic mixture of Bacillus subtilis and Enterococcu…
View article: Textural properties and morphology of soy 7S globulin-corn starch (amylose, amylopectin)
Textural properties and morphology of soy 7S globulin-corn starch (amylose, amylopectin) Open
The texture properties (hardness, adhesiveness, cohesion, elasticity) of composite gels with different ratios (0:100, 6:94, 8:92, 10:90, 12:88, and 14:86, respectively) of soy 7S globulin to corn starch (amylose, amylopectin) were studied.…
View article: Third-Generation Sequencing and Analysis of Four Complete Pig Liver Esterase Gene Sequences in Clones Identified by Screening BAC Library
Third-Generation Sequencing and Analysis of Four Complete Pig Liver Esterase Gene Sequences in Clones Identified by Screening BAC Library Open
This is the first report to confirm the complete sequences of four PLE genes. In addition, the study demonstrates that each PLE isoform is encoded by a single gene and that the various genes exhibit a high degree of sequence homology, sugg…
View article: Chicken gga-miR-19a Targets ZMYND11 and Plays an Important Role in Host Defense against Mycoplasma gallisepticum (HS Strain) Infection
Chicken gga-miR-19a Targets ZMYND11 and Plays an Important Role in Host Defense against Mycoplasma gallisepticum (HS Strain) Infection Open
Mycoplasma gallisepticum (MG), one of the most pathogenic Mycoplasmas, can cause chronic respiratory disease (CRD) in chickens. It has been suggested that micro-ribonucleic acids (miRNAs) are involved in microbial pathogenesis. However, li…
View article: Correction: Corrigendum: The Cipher Code of Simple Sequence Repeats in “Vampire Pathogens”
Correction: Corrigendum: The Cipher Code of Simple Sequence Repeats in “Vampire Pathogens” Open
Scientific Reports 5: Article number: 12441; published online: 28 July 2015; updated: 23 August 2016 In this Article, there is a typographical error in the Acknowledgments section. “This work was supported by grants from National Natural S…
View article: Research on the Technology of Inhibiting Browning in Chestnut Paste Processing
Research on the Technology of Inhibiting Browning in Chestnut Paste Processing Open
Chestnut (Castanea mollissima) is a multipurpose species that is cultivated for timber, nut, tannin and contributes positively to the forestry landscape. It is important in chestnut paste processing to prevent the chestnuts browning. For t…
View article: <i>Enterococcus faecium</i>HDRsEf1 Protects the Intestinal Epithelium and Attenuates ETEC-Induced IL-8 Secretion in Enterocytes
<i>Enterococcus faecium</i>HDRsEf1 Protects the Intestinal Epithelium and Attenuates ETEC-Induced IL-8 Secretion in Enterocytes Open
The probiotic Enterococcus faecium HDRsEf1 (Ef1) has been shown to have positive effects on piglet diarrhoea, but the mechanism has not yet been elucidated. In this study, using the IPEC-J2 cell line to mimic intestinal epithelial cells an…
View article: gga-miR-101-3p Plays a Key Role in Mycoplasma gallisepticum (HS Strain) Infection of Chicken
gga-miR-101-3p Plays a Key Role in Mycoplasma gallisepticum (HS Strain) Infection of Chicken Open
Mycoplasma gallisepticum (MG), one of the most pathogenic Mycoplasma, has caused tremendous economic loss in the poultry industry. Recently, increasing evidence has suggested that micro ribonucleic acids (miRNAs) are involved in microbial …
View article: Draft Genome Sequence of Listeria monocytogenes LM201, Isolated from Foodstuff
Draft Genome Sequence of Listeria monocytogenes LM201, Isolated from Foodstuff Open
Listeria monocytogenes is a facultative intracellular foodborne pathogen that can cause listeriosis in humans and animals. L. monocytogenes LM201 was isolated from foodstuff. The draft genome sequence of strain LM201 provides the genetic b…
View article: Complete mitochondrial genome of the Chinese Hwamei Garrulax canorus (Aves: Passeriformes): the first representative of the Leiothrichidae family with a duplicated control region
Complete mitochondrial genome of the Chinese Hwamei Garrulax canorus (Aves: Passeriformes): the first representative of the Leiothrichidae family with a duplicated control region Open
The Chinese Hwamei Garrulax canorus, a member of the family Leiothrichidae, is commonly found in central and southern China, northern Indochina, and on Hainan Island. In this study, we sequenced the complete mitochondrial genome of G. cano…