Rena Okawa
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View article: Evaluation of Streptococcus mutans strains possessing genes encoding collagen-binding proteins in the Japanese population
Evaluation of Streptococcus mutans strains possessing genes encoding collagen-binding proteins in the Japanese population Open
Background Streptococcus mutans harbors collagen-binding protein genes, namely cnm and cbm , which are implicated in its virulence and pathogenicity in both oral and extraoral infections. Although both genes were initially identified in S.…
View article: Effect of Pembrolizumab on Lymph Node Dissection in Patients Who Experienced Bladder Cancer Recurrence Following Radical Cystectomy
Effect of Pembrolizumab on Lymph Node Dissection in Patients Who Experienced Bladder Cancer Recurrence Following Radical Cystectomy Open
Lymph node resection was not associated with prognosis and efficacy of pembrolizumab in patients with bladder cancer. However, as the resection of more than 14 lymph nodes was associated with a poorer prognosis and reduced efficacy of pemb…
View article: Efficacy of prostatectomy using a Retzius‐sparing approach as an additional excision in anal canal carcinoma after brachytherapy for prostate adenocarcinoma
Efficacy of prostatectomy using a Retzius‐sparing approach as an additional excision in anal canal carcinoma after brachytherapy for prostate adenocarcinoma Open
Introduction Standard treatments for squamous cell carcinoma of the anal canal include chemoradiotherapy and surgical resection. We report a rare case of squamous cell carcinoma of the anal canal with prostate invasion treated with curativ…
View article: Japanese nationwide dental survey of hypophosphatasia reveals novel oral manifestations
Japanese nationwide dental survey of hypophosphatasia reveals novel oral manifestations Open
Hypophosphatasia (HPP) is a common inherited skeletal disease. Early exfoliation of primary teeth is known as a dental manifestation of HPP, and sometimes this symptom leads to a diagnosis of HPP. This study aimed to investigate the dental…
View article: Multilocus sequence typing and phenotypic properties of Streptococcus mutans from Thai children with different caries statuses
Multilocus sequence typing and phenotypic properties of Streptococcus mutans from Thai children with different caries statuses Open
Background Streptococcus mutans is studied for its acidogenic and aciduric characteristics, notably its biofilm formation in the presence of sucrose, toward its role in the caries process. Variations in both genotype and phenotype have bee…
View article: Inhibitory Effects of Surface Pre-Reacted Glass Ionomer Filler Eluate on Streptococcus mutans in the Presence of Sucrose
Inhibitory Effects of Surface Pre-Reacted Glass Ionomer Filler Eluate on Streptococcus mutans in the Presence of Sucrose Open
The surface pre-reacted glass ionomer (S-PRG) filler is a type of bioactive functional glass that releases six different ions. This study examined the effects of the S-PRG filler eluate on Streptococcus mutans in the presence of sucrose. I…
View article: Evaluation of dental manifestations in X-linked hypophosphatemia using orthopantomography
Evaluation of dental manifestations in X-linked hypophosphatemia using orthopantomography Open
Background X-linked hypophosphatemia (XLH) is the most common inherited form of rickets. The presence of sequence variations in the phosphate regulating endopeptidase homolog X-linked (PHEX) gene is associated with increased production of …
View article: Effects of mouthwash on periodontal pathogens and glycemic control in patients with type 2 diabetes mellitus
Effects of mouthwash on periodontal pathogens and glycemic control in patients with type 2 diabetes mellitus Open
Periodontitis is known to be associated with type 2 diabetes mellitus (T2DM), and gargling with mouthwash is known to reduce the incidence of periodontitis by inhibiting periodontal pathogens. However, the effects of mouthwash on oral and …
View article: Panoramic Radiograph Generation and Image Reconstruction from Latent Vectors Using a Generative Adversarial Network
Panoramic Radiograph Generation and Image Reconstruction from Latent Vectors Using a Generative Adversarial Network Open
In this study, StyleGAN2 was trained with panoramic radiographs, and original images were projected into the latent space of StyleGAN2. The resulting latent vectors were input into StyleGAN2, and corresponding images were generated to reco…
View article: Inhibitory Effects of Shikonin Dispersion, an Extract of Lithospermum erythrorhizon Encapsulated in β-1,3-1,6 Glucan, on Streptococcus mutans and Non-Mutans Streptococci
Inhibitory Effects of Shikonin Dispersion, an Extract of Lithospermum erythrorhizon Encapsulated in β-1,3-1,6 Glucan, on Streptococcus mutans and Non-Mutans Streptococci Open
Shikonin is extracted from the roots of Lithospermum erythrorhizon, and shikonin extracts have been shown to have inhibitory effects on several bacteria. However, shikonin extracts are difficult to formulate because of their poor water sol…
View article: Tooth Development Prediction Using a Generative Machine Learning Approach
Tooth Development Prediction Using a Generative Machine Learning Approach Open
Kokomoto K., Okawa R., Nakano K., et al. Tooth Development Prediction Using a Generative Machine Learning Approach. IEEE Access 12, 87645 (2024); https://doi.org/10.1109/ACCESS.2024.3416748.
View article: Automatic dental age calculation using orthopantomogram and deep learning
Automatic dental age calculation using orthopantomogram and deep learning Open
Background: Dental age is crucial for treatment planning in pediatric and orthodontic dentistry. Dental age calculation methods can be categorized into morphological, biochemical, and radiological methods. Radiological methods are commonly…
View article: Inhibitory Effect of Adsorption of Streptococcus mutans onto Scallop-Derived Hydroxyapatite
Inhibitory Effect of Adsorption of Streptococcus mutans onto Scallop-Derived Hydroxyapatite Open
Hydroxyapatite adsorbs various substances, but little is known about the effects on oral bacteria of adsorption onto hydroxyapatite derived from scallop shells. In the present study, we analyzed the effects of adsorption of Streptococcus m…
View article: In vitro analysis of durability of S-PRG filler-containing composite crowns for primary molar restoration
In vitro analysis of durability of S-PRG filler-containing composite crowns for primary molar restoration Open
The crowns fabricated with the experimental CAD/CAM RC incorporating S-PRG filler yielded greater fracture loads and reliability than the crowns manufactured with commercially available CAD/CAM RC regardless of the luting materials. These …
View article: Sublingual Dermoid Cyst in Young Child
Sublingual Dermoid Cyst in Young Child Open
A dermoid cyst is a benign congenital lesion of ectodermal origin that can arise in any region of the body, though occurrence is rare. A young girl aged 2 years 4 months was referred to our hospital because of a painless mass in the floor …
View article: Effect of Conventional Treatment on Dental Complications and Ectopic Ossifications Among 30 Adults With XLH
Effect of Conventional Treatment on Dental Complications and Ectopic Ossifications Among 30 Adults With XLH Open
Context Conventional treatment of X-linked hypophosphatemia (XLH) was reported to prevent dental complications, but whether the preventive effect was different among different types of teeth, including anterior teeth and molar teeth, is un…
View article: Osteomyelitis Possibly Caused by Exfoliation of Primary Teeth in a Patient with Osteopetrosis
Osteomyelitis Possibly Caused by Exfoliation of Primary Teeth in a Patient with Osteopetrosis Open
Osteopetrosis is a rare inherited skeletal disease characterized by increased density in the bones and can be detected by radiographs. Sclerosis makes the jaw bones extremely susceptible to infections, osteomyelitis, and fractures. Here, w…
View article: Different Dental Manifestations in Sisters with the Same ALPL Gene Mutation: A Report of Two Cases
Different Dental Manifestations in Sisters with the Same ALPL Gene Mutation: A Report of Two Cases Open
Hypophosphatasia (HPP) is an inherited disease caused by mutation of the alkaline phosphatase (ALPL) gene in an autosomal dominant or an autosomal recessive manner. The main symptoms of HPP are bone hypomineralization and early exfoliation…
View article: Large-Scale Survey of Missing Deciduous Anterior Teeth on Medical Examination at the Age of 3.5 Years
Large-Scale Survey of Missing Deciduous Anterior Teeth on Medical Examination at the Age of 3.5 Years Open
Tooth anomalies in childhood may negatively affect the healthy development of the dentition and occlusion; hence, it is important to examine the actual oral condition at an early stage. The present study was performed to understand the sta…
View article: Dental Manifestations and Oral Management of X-Linked Hypophosphatemia
Dental Manifestations and Oral Management of X-Linked Hypophosphatemia Open
X-linked hypophosphatemia (XLH) is the most common genetic form of rickets and osteomalacia and is characterized by growth retardation, deformities of the lower limbs, and bone and muscular pain. Spontaneous dental abscesses caused by endo…
View article: A Case of X-Linked Hypophosphatemic Rickets with Dentin Dysplasia in Mandibular Third Molars
A Case of X-Linked Hypophosphatemic Rickets with Dentin Dysplasia in Mandibular Third Molars Open
X-linked hypophosphatemic rickets (XLH) is a disease characterized by impaired bone mineralization, and its dental features include gingival abscesses and large pulp spaces due to dentin dysplasia. A 20-year-old woman with XLH was referred…
View article: Evaluation of alveolar bone hypomineralization in pediatric hypophosphatasia using orthopantomography
Evaluation of alveolar bone hypomineralization in pediatric hypophosphatasia using orthopantomography Open
Hypophosphatasia (HPP) is a metabolic disease characterized by impaired bone mineralization and early exfoliation of primary teeth. This study was performed to develop a method for quantitatively evaluating alveolar bone hypomineralization…