Renan O. Silva
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View article: Phytochemistry and Anti-Inflammatory and Antioxidant Activities of Cinnamomum osmophloeum and Its Bioactive Constituents: A Review
Phytochemistry and Anti-Inflammatory and Antioxidant Activities of Cinnamomum osmophloeum and Its Bioactive Constituents: A Review Open
Cinnamomum osmophloeum, commonly known as indigenous cinnamon, is a tree species native to Taiwan’s hardwood forests. It has been extensively investigated for its chemical composition and bioactivities. Several reports have shown that C. o…
View article: Bacillus clausii Attenuates 5-Fluorouracil-Induced Intestinal Mucositis in Mice
Bacillus clausii Attenuates 5-Fluorouracil-Induced Intestinal Mucositis in Mice Open
5-Fluorouracil (5-FU) is an antimetabolite widely prescribed in cancer treatments, but its use in highly proliferative tissues can cause significant problems such as mucositis. Bacillus clausii is a probiotic commonly used for protection a…
View article: Iota-Carrageenan from Marine Alga Solieria filiformis Prevents Naproxen-Induced Gastrointestinal Injury via Its Antioxidant and Anti-Inflammatory Activities
Iota-Carrageenan from Marine Alga Solieria filiformis Prevents Naproxen-Induced Gastrointestinal Injury via Its Antioxidant and Anti-Inflammatory Activities Open
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in therapy due to their anti-inflammatory and analgesic properties. However, their clinical use is often associated with gastrointestinal complications. Thus, this …
View article: Anti-Inflammatory and Antioxidant Activities of Eugenol: An Update
Anti-Inflammatory and Antioxidant Activities of Eugenol: An Update Open
Medicinal plants are a rich source of bioactive compounds that possess pharmacological properties for preventing and treating inflammation-related diseases. Essential oils is a chemical class that contains many bioactive compounds, such as…
View article: Novos biomarcadores séricos para o diagnóstico de pacientes com colite ulcerativa
Novos biomarcadores séricos para o diagnóstico de pacientes com colite ulcerativa Open
Objetivo: realizar uma revisão da literatura sobre possíveis marcadores séricos em pacientes com RU com o objetivo de identificar potenciais biomarcadores. Métodos: os descritores “Colitis Ulcerative”, “Biomarkers” e “Diagnosis” foram util…
View article: Essential Oils: Chemistry and Pharmacological Activities
Essential Oils: Chemistry and Pharmacological Activities Open
In this review, we provide an overview of the current understanding of the main mechanisms of pharmacological action of essential oils and their components in various biological systems. A brief introduction on essential oil chemistry is p…
View article: A novel experimental procedure for lock-in thermography on solar cells
A novel experimental procedure for lock-in thermography on solar cells Open
The occurrence of defects in solar cells is intrinsically related to a reduction in the efficiency and reliability of these devices. Therefore, monitoring techniques, such as lock-in thermography, electroluminescence and the I-V character…
View article: Peptide Isolated from Noni Seeds Confers Gastroprotective Effect by Improving Inflammation and Oxidative Stress in Mice
Peptide Isolated from Noni Seeds Confers Gastroprotective Effect by Improving Inflammation and Oxidative Stress in Mice Open
Plant molecules are continuously investigated to prevent and treat inflammatory and ulcerative disorders associated with the gastrointestinal tract, such as gastritis, colitis, mucositis, and ulcer. However, most of the work published is d…
View article: Lactobacillus reuteri DSM 17938 Protects against Gastric Damage Induced by Ethanol Administration in Mice: Role of TRPV1/Substance P Axis
Lactobacillus reuteri DSM 17938 Protects against Gastric Damage Induced by Ethanol Administration in Mice: Role of TRPV1/Substance P Axis Open
This study aimed to evaluate the effect of Lactobacillus reuteri DSM 17938 (DSM) on ethanol-induced gastric injury, and if its possible mechanism of action is related to inhibiting the transient receptor potential vanilloid type 1 (TRPV1).…
View article: Neutrophils contribute to the pathogenesis of hemorrhagic cystitis induced by ifosfamide
Neutrophils contribute to the pathogenesis of hemorrhagic cystitis induced by ifosfamide Open
View article: An Overview on the Anti‐inflammatory Potential and Antioxidant Profile of Eugenol
An Overview on the Anti‐inflammatory Potential and Antioxidant Profile of Eugenol Open
The bioactive compounds found in foods and medicinal plants are attractive molecules for the development of new drugs with action against several diseases, such as those associated with inflammatory processes, which are commonly related to…
View article: Envolvimento do receptor TRPV1 em um novo modelo de doença do refluxo não erosiva (NERD): da inflamação ao defeito funcional
Envolvimento do receptor TRPV1 em um novo modelo de doença do refluxo não erosiva (NERD): da inflamação ao defeito funcional Open
Non-erosive reflux disease (NERD) affects about 70% of patients with reflux symptoms. These patients do not present erosions in the esophageal mucosa at endoscopy, but exhibit impaired epithelial integrity and increased expression of trans…
View article: Nitric Oxide and Hydrogen Sulfide Interact When Modulating Gastric Physiological Functions in Rodents
Nitric Oxide and Hydrogen Sulfide Interact When Modulating Gastric Physiological Functions in Rodents Open
View article: Delivery system for mefenamic acid based on the nanocarrier layered double hydroxide: Physicochemical characterization and evaluation of anti-inflammatory and antinociceptive potential
Delivery system for mefenamic acid based on the nanocarrier layered double hydroxide: Physicochemical characterization and evaluation of anti-inflammatory and antinociceptive potential Open
View article: Laticifer proteins from Plumeria pudica inhibit the inflammatory and nociceptive responses by decreasing the action of inflammatory mediators and pro-inflammatory cytokines
Laticifer proteins from Plumeria pudica inhibit the inflammatory and nociceptive responses by decreasing the action of inflammatory mediators and pro-inflammatory cytokines Open
Some publications have described the pharmacological properties of latices proteins. Thus, in the present study proteins from Plumeria pudica Jacq., Apocynaceae, latex were evaluated for anti-inflammatory and antinociceptive activities. Ob…
View article: Polysaccharide fraction isolated from<i>P</i><i>assiflora edulis</i>inhibits the inflammatory response and the oxidative stress in mice
Polysaccharide fraction isolated from<i>P</i><i>assiflora edulis</i>inhibits the inflammatory response and the oxidative stress in mice Open
Objectives The aim of the study was to investigate the anti-inflammatory, antioxidant and antinociceptive actions of PFPe, a polysaccharide fraction isolated from the dried fruit of the Passiflora edulis. Methods Animals were pretreated wi…
View article: The role of nitric oxide in alendronate-mediated acceleration of gastric emptying and gastrointestinal transit in rats
The role of nitric oxide in alendronate-mediated acceleration of gastric emptying and gastrointestinal transit in rats Open
The effect of the alendronate (ALD; 30 mg/kg, pH 7.0, p.o.) and sodium nitroprusside (SNP; 10 mg/kg, p.o.; a nitric oxide (NO) donor) on gastric dye retention (GDR) and proximal, medial and distal small intestine dye retentions (IDR) was i…