Renata Hajdu
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View article: The unfolded protein response regulates ER exit sites via SNRPB-dependent RNA splicing and contributes to bone development
The unfolded protein response regulates ER exit sites via SNRPB-dependent RNA splicing and contributes to bone development Open
Splicing and endoplasmic reticulum (ER)-proteostasis are two key processes that ultimately regulate the functional proteins that are produced by a cell. However, the extent to which these processes interact remains poorly understood. Here,…
View article: Identification of a link between splicing and endoplasmic reticulum proteostasis
Identification of a link between splicing and endoplasmic reticulum proteostasis Open
The role of general splicing in endoplasmic reticulum (ER)-proteostasis remains poorly understood. Here, we identify SNRPB, a component of the spliceosome, as a novel regulator of export from the ER. Mechanistically, SNRPB regulates the sp…