Alireza Shirazi
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View article: Evaluating food contact surface and its influence on restaurant health ratings
Evaluating food contact surface and its influence on restaurant health ratings Open
View article: Apigenin-Melatonin: a novel prostate cancer Radiation Sensitizer
Apigenin-Melatonin: a novel prostate cancer Radiation Sensitizer Open
Background : Radiotherapy is a common modality in prostate cancer (PrCa), with a dose of 80Gy. A higher dose of ionizing radiation is often needed to achieve an appropriate response; however, clinical evidence indicates that increasing the…
View article: 3D in vivo dosimetry of HDR gynecological brachytherapy using micro silica bead TLDs
3D in vivo dosimetry of HDR gynecological brachytherapy using micro silica bead TLDs Open
Purpose This study aimed to evaluate the feasibility of defining an in vivo dosimetry (IVD) protocol as a patient‐specific quality assurance (PSQA) using the bead thermoluminescent dosimeters (TLDs) for point and 3D IVD during brachytherap…
View article: An In-Vitro Study on Photochemical Internalization of Methylene Blue with Gold Nanoparticles Coated By Thio-Glucose
An In-Vitro Study on Photochemical Internalization of Methylene Blue with Gold Nanoparticles Coated By Thio-Glucose Open
Objectives: Photochemical internalization (PCI) is a novel PDT-based technology for intracellular delivery of hydrophilic macromolecular therapeutic agents and other drugs with limited ability to penetrate cellular membranes with intracell…
View article: Fatigue damage modeling based on cracking progress in unidirectional and cross-ply FRP composites
Fatigue damage modeling based on cracking progress in unidirectional and cross-ply FRP composites Open
The present study intends to investigate the fatigue damage response of various off-axis unidirectional and cross-ply fiber-reinforced polymer (FRP) composite laminates. A fatigue damage analysis for these composites has been developed bas…
View article: A hybrid approach to characterization and life assessment of trilayer assemblies of dissimilar materials under thermal cycles
A hybrid approach to characterization and life assessment of trilayer assemblies of dissimilar materials under thermal cycles Open
The current study puts forward non-local closed-form solutions for interfacial peel and shear stress, as well as warpage deformation, of trilayer structures under thermal cycling. Based on the solution, a hybrid experimental-analytical inv…
View article: Evaluation of ferrous benzoic methylthymol-blue gel as a dosimeter via magnetic resonance imaging
Evaluation of ferrous benzoic methylthymol-blue gel as a dosimeter via magnetic resonance imaging Open
View article: Development of a novel and low-cost anthropomorphic pelvis phantomfor 3D dosimetry in radiotherapy
Development of a novel and low-cost anthropomorphic pelvis phantomfor 3D dosimetry in radiotherapy Open
A customized pelvis phantom was successfully built and assessed to confirm properties similar to body tissues. Additionally, no significant perturbation effect with different bead resolutions was presented by the external TPS, with 0.1 mm …
View article: The radioprotective effect of melatonin against radiation-induced DNA double-strand breaks in radiology
The radioprotective effect of melatonin against radiation-induced DNA double-strand breaks in radiology Open
The present study showed that melatonin will prove effective in radioprotection against ionizing radiation (IR)-induced DNA damage in human lymphocytes. Our results suggest ingestion of 100-mg melatonin by patients before exposure to IR in…
View article: Brachial Plexopathy as a Complication of Radiotherapy: A Systematic Review
Brachial Plexopathy as a Complication of Radiotherapy: A Systematic Review Open
Background: Radiotherapy is a commonly used cancer treatment modality. However, radiation-induced complications are major drawbacks, especially at high doses. Radiation-induced brachial plexopathy (RIBP) is mostly observed in breast and lu…
View article: The effect of melatonin on Superoxide dismutase and Glutathione peroxidase activity, and Malondialdehyde levels in the targeted and the non-targeted lung and heart tissues after irradiation in xenograft mice colon cancer
The effect of melatonin on Superoxide dismutase and Glutathione peroxidase activity, and Malondialdehyde levels in the targeted and the non-targeted lung and heart tissues after irradiation in xenograft mice colon cancer Open
Introduction: Introduction: Radiation causes damage to irradiated tissues and also tissues that do not receive direct irradiation through a phenomenon called bystander effects. Melatonin as a potent antioxidant and anti-inflammatory agent …
View article: Study the effect of source to diaphragm distance (SDD) on beam penumbra width of Gamma Knife machine model 4C using Monte Carlo simulation
Study the effect of source to diaphragm distance (SDD) on beam penumbra width of Gamma Knife machine model 4C using Monte Carlo simulation Open
Introduction: Stereotactic radiosurgery (SRS) is one of the conformal radiotherapy methods and Gamma Knife is a non-invasive SRS technique to treat intracranial lesions with 201 Co- 60 sources without need to surgery and bleeding. Beam pen…
View article: Evaluating the expression of cyclooxygenase-2 enzyme by immunohistochemistry in normal and tumoral tissue before and after neoadjuvant chemoradiotherapy in patients with esophageal cancer in Khorasan Province
Evaluating the expression of cyclooxygenase-2 enzyme by immunohistochemistry in normal and tumoral tissue before and after neoadjuvant chemoradiotherapy in patients with esophageal cancer in Khorasan Province Open
The results indicated that expression of COX-2 in tumoral tissues exceeds the expression of COX-2 in normal tissue of the baseline biopsy. Patients with a high expression of COX-2 in baseline tumor biopsies had less response to treatment o…
View article: Radioprotective effect of melatonin on expression of Cdkn1a and Rad50 genes in rat peripheral blood
Radioprotective effect of melatonin on expression of Cdkn1a and Rad50 genes in rat peripheral blood Open
Based on our results, pretreatment with melatonin (100 mg/kg) may ameliorates injurious effects of 2 and 8 Gy ionization radiation by increasing the expression level of Cdkn1a and Rad50 in rat peripheral blood and assist in DNA double-stra…
View article: The Effect of Breast Reconstruction Prosthesis on Photon Dose Distribution in Breast Cancer Radiotherapy
The Effect of Breast Reconstruction Prosthesis on Photon Dose Distribution in Breast Cancer Radiotherapy Open
Introduction: Siliconeprosthetic implants are commonlyutilizedfor tissue replacement and breast augmentation after mastectomy. On the other hand, some patients require adjuvant radiotherapy in order to preventlocal-regional recurrence and …
View article: Dosimetric characteristics of LinaTech DMLC H multi leaf collimator: Monte Carlo simulation and experimental study
Dosimetric characteristics of LinaTech DMLC H multi leaf collimator: Monte Carlo simulation and experimental study Open
This study evaluated the basic dosimetric characteristics of a Dynamic Multi Leaf Collimator (DMLC) using a diode detector and film measurements for Intensity Modulated Radiation Therapy Quality Assurance (IMRT QA). The EGSnrc Monte Carlo …
View article: Expression Levels of Two DNA Repair-related Genes under 8 Gy Ionizing Radiation and 100 Mg/Kg Melatonin Delivery In Rat Peripheral Blood.
Expression Levels of Two DNA Repair-related Genes under 8 Gy Ionizing Radiation and 100 Mg/Kg Melatonin Delivery In Rat Peripheral Blood. Open
We concluded that, by increasing expression level of Ku70 and Xrcc4 genes, 100 mg/kg melatonin administration 8 and 24 h before 8 Gyionizing radiation can significantly affect the repair of DNA DSBs in NHEJ pathway.
View article: Modulation of radiation-induced base excision repair pathway gene expression by melatonin
Modulation of radiation-induced base excision repair pathway gene expression by melatonin Open
Our results suggested that MLT in mentioned dose may result in modulation of Ogg1, Apex1, and Xrcc1 gene expression in peripheral blood cells to reduce X-ray irradiation-induced DNA damage. Therefore, administration of…
View article: Introducing a Novel Method for Three Dimensional Dose Map by Optical Computed Tomography
Introducing a Novel Method for Three Dimensional Dose Map by Optical Computed Tomography Open
Background: Radiochromic gel is recently introduced as a three dimensional dosimeter that exhibits color changes by being exposed to ionizing radiation. Therefore, the read-out system of this dosimeter should be based on radiochromic respo…
View article: Evaluating the effect of Zinc Oxide nanoparticles doped with Gadolinium on dose enhancement factor by PRESAGE dosimeter
Evaluating the effect of Zinc Oxide nanoparticles doped with Gadolinium on dose enhancement factor by PRESAGE dosimeter Open
Evaluating the effect of Zinc Oxide nanoparticles doped with Gadolinium on dose enhancement factor by PRESAGE dosimeter
View article: Prophylactic role of some plants and phytochemicals against radio-genotoxicity in human lymphocytes
Prophylactic role of some plants and phytochemicals against radio-genotoxicity in human lymphocytes Open
Genotoxicity in lymphocytes of cancer patients undergoing radiotherapy can lead to lymphocytopenia. Lymphocytopenia induced by radiotherapy is one of the most unfavorable prognostic biological markers in cancer patients, since it has been …
View article: Experimental Evaluation of Depth Dose by Exit Surface Diode Dosimeters for Off-Axis Wedged Fields in Radiation Therapy
Experimental Evaluation of Depth Dose by Exit Surface Diode Dosimeters for Off-Axis Wedged Fields in Radiation Therapy Open
Introduction Evaluation of the delivered dose of externally wedged photon beams by external diode dosimeters during the treatment process requires the estimation of exit surface dose correction factors in various wedge angles and field siz…
View article: Validation of a Prototype Optical Computed Tomography System
Validation of a Prototype Optical Computed Tomography System Open
In radiation cancer treatments, the most of the side effects could be minimized using a proper dosimeter. Gel dosimeter is the only three-dimensional dosimeter and magnetic resonance imaging (MRI) is the gold standard method for gel dosime…
View article: Candidate gene biodosimeters of mice and human exposure to ionizing radiation by quantitative reverse transcription polymerase chain reaction
Candidate gene biodosimeters of mice and human exposure to ionizing radiation by quantitative reverse transcription polymerase chain reaction Open
Understanding of cellular responses to ionizing radiation (IR) is essential for the development of predictive markers useful for assessing human exposure. Biological markers of exposure to IR in human populations are of great interest for …