Reza Vahidi
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View article: 6-Gingerol modulates miRNAs and PODXL gene expression via methyltransferase enzymes in NB4 cells: an in silico and in vitro study
6-Gingerol modulates miRNAs and PODXL gene expression via methyltransferase enzymes in NB4 cells: an in silico and in vitro study Open
This investigation delves into the influence of predicted microRNAs on DNA methyltransferases (DNMTs) and the PODXL gene within the NB4 cell line, aiming to elucidate their roles in the pathogenesis of acute myeloid leukemia (AML). A compr…
View article: Catechin-Induced changes in PODXL, DNMTs, and miRNA expression in Nalm6 cells: an integrated in silico and in vitro approach
Catechin-Induced changes in PODXL, DNMTs, and miRNA expression in Nalm6 cells: an integrated in silico and in vitro approach Open
View article: Modulation of IKK/NF-κB Signaling: A Therapeutic Mechanism of Shilajit in Breast Cancer Cells
Modulation of IKK/NF-κB Signaling: A Therapeutic Mechanism of Shilajit in Breast Cancer Cells Open
Background: Shilajit is a natural pale-brown to blackish-brown phytocomplex that exudes from mountain rocks in various parts of the world. In recent years, numerous pharmacological effects of shilajit have been explored through extensive e…
View article: Catechin-induced changes in PODXL, DNMTs, and miRNA expression in NALM6 cells: An integrated in silico and in vitro approach
Catechin-induced changes in PODXL, DNMTs, and miRNA expression in NALM6 cells: An integrated in silico and in vitro approach Open
Background This study explored the impact of predicted miRNAs on DNA methyltransferases (DNMTs) and thePODXLgene in NALM6 cells, revealing the significance of these miRNAs in acute lymphocytic leukemia (ALL). Methods We employed a multifac…
View article: MicroRNAs: Potential prognostic and theranostic biomarkers in chronic lymphocytic leukemia
MicroRNAs: Potential prognostic and theranostic biomarkers in chronic lymphocytic leukemia Open
Small noncoding ribonucleic acids called microRNAs coordinate numerous critical physiological and biological processes such as cell division, proliferation, and death. These regulatory molecules interfere with the function of many genes by…
View article: Hydrogel nanocomposite based on alginate/zeolite for burn wound healing: <i>In vitro</i> and <i>in vivo</i> study.
Hydrogel nanocomposite based on alginate/zeolite for burn wound healing: <i>In vitro</i> and <i>in vivo</i> study. Open
These findings revealed that although the incorporation of zeolites did not induce a significant beneficial effect in comparison with Alg hydrogel, using zeolite capacity in hydrogel for loading the antibiotics or other effective compounds…
View article: Kermanian propolis induces apoptosis through upregulation of Bax/Bcl-2 ratio in acute myeloblastic leukemia cell line (NB4)
Kermanian propolis induces apoptosis through upregulation of Bax/Bcl-2 ratio in acute myeloblastic leukemia cell line (NB4) Open
Objective: Propolis is a viscous resinous honeybee-produced substance with numerous medicinal functions; its composition and texture varies according to the geographic location. It is considered to be a promising natural source for the man…
View article: Elevated Bax/Bcl-2 Ratio: A Cytotoxic Mode of Action of Kermanian Propolis Against an Acute Lymphoblastic Leukemia Cell Line, NALM-6
Elevated Bax/Bcl-2 Ratio: A Cytotoxic Mode of Action of Kermanian Propolis Against an Acute Lymphoblastic Leukemia Cell Line, NALM-6 Open
View article: Predicting the possible effect of miR-203a-3p and miR-29a-3p on <i>DNMT3B</i> and <i>GAS7</i> genes expression
Predicting the possible effect of miR-203a-3p and miR-29a-3p on <i>DNMT3B</i> and <i>GAS7</i> genes expression Open
Aberrant expression of genes involved in methylation, including DNA methyltransferase 3 Beta ( DNMT3B ), can cause hypermethylation of various tumor suppressor genes. In this regard, various molecular factors such as microRNAs can play a c…
View article: High resolution melting analysis and detection of Leishmania resistance: the role of multi drug resistance 1 gene
High resolution melting analysis and detection of Leishmania resistance: the role of multi drug resistance 1 gene Open
View article: Ubiquitous convalescent plasma: An artificial universal plasma for COVID-19 patients
Ubiquitous convalescent plasma: An artificial universal plasma for COVID-19 patients Open
View article: Band 3 Protein: An Effective Interrogation Tool of Storage Lesions in RBC Units
Band 3 Protein: An Effective Interrogation Tool of Storage Lesions in RBC Units Open
View article: Green Synthesis of Stable Silver Nanoparticles Using Teucrium polium Extract: In-vitro Anticancer Activity on NALM-6
Green Synthesis of Stable Silver Nanoparticles Using Teucrium polium Extract: In-vitro Anticancer Activity on NALM-6 Open
The therapeutic effect of silver nanoparticles on leukaemia cancerous cells has been demonstrated in several studies. However, most of these nanoparticles are toxic to normal cells as well as cancerous cells. In the present study, green ch…
View article: Bcl<sub>2</sub>-dependent antineoplastic effects of <i>Calotropis procera</i> root extract against canine mammary tumor cells.
Bcl<sub>2</sub>-dependent antineoplastic effects of <i>Calotropis procera</i> root extract against canine mammary tumor cells. Open
There has been a prevailing trend in the application of herbal medicine as cancer therapeutics. Calotropis procera is an ayurvedic plant applied to ameliorate various illnesses. There is no report on the anti-tumor effects of the ro…
View article: Cord blood serum harvesting by hydroxyethyl starch: a fetal bovine serum alternative in expansion of umbilical cord-derived mesenchymal stem cells
Cord blood serum harvesting by hydroxyethyl starch: a fetal bovine serum alternative in expansion of umbilical cord-derived mesenchymal stem cells Open
View article: High Resolution Melting Analysis in Leishmania Resistance: The Role of Multi Drug Resistance 1 Gene
High Resolution Melting Analysis in Leishmania Resistance: The Role of Multi Drug Resistance 1 Gene Open
Objective Pentavalent antimonial compounds are currently used to treat Leishmaniasis. Resistance to these drugs is a serious problem. The purpose of this study was to evaluate the mutations in the multi-drug resistance 1 (MDR1) gene in bio…
View article: Evaluation of MDR1 and MRPA genes expression in different types of dry cutaneous leishmaniasis
Evaluation of MDR1 and MRPA genes expression in different types of dry cutaneous leishmaniasis Open
Objective The resistance to antimony-containing glucantime is a major obstacle to successful treatment, especially in endemic areas. Looking the molecular mechanisms involved in this drug resistance will help in choosing the best treatment…
View article: Ability of Real-time PCR for Differential Diagnosis of Various Forms of Cutaneous Leishmaniasis: A Comparative Study with Histopathology
Ability of Real-time PCR for Differential Diagnosis of Various Forms of Cutaneous Leishmaniasis: A Comparative Study with Histopathology Open
objective: Histopathological studies suggest that parasite load is different between acute and chronic forms of cutaneous leishmaniasis (CL). However, highly sensitive detection methods are still needed to distinguish different forms of le…
View article: Ability of real-time PCR for differential diagnosis of various forms of cutaneous leishmaniasis: a comparative study with histopathology
Ability of real-time PCR for differential diagnosis of various forms of cutaneous leishmaniasis: a comparative study with histopathology Open
View article: Ability of Real-time PCR for Differential Diagnosis of Various Forms of Cutaneous Leishmaniasis: A Comparative Study with Histopathology
Ability of Real-time PCR for Differential Diagnosis of Various Forms of Cutaneous Leishmaniasis: A Comparative Study with Histopathology Open
objective: Histopathological studies suggest that parasite load is different between acute and chronic forms of cutaneous leishmaniasis (CL). However, highly sensitive detection methods are still needed to distinguish different forms of le…
View article: Ability of Real-time PCR for Differential Diagnosis of Various Forms of Cutaneous Leishmaniasis: A Comparative Study with Histopathology
Ability of Real-time PCR for Differential Diagnosis of Various Forms of Cutaneous Leishmaniasis: A Comparative Study with Histopathology Open
objective: Histopathological studies suggest that parasite load is different between acute and chronic forms of cutaneous leishmaniasis (CL). However, highly sensitive detection methods are still needed to distinguish different forms of le…
View article: Ability of Real-time PCR in diagnose Differentiation Various Forms of Cutaneous Leishmaniasis: A Comparative Study with Histopathology
Ability of Real-time PCR in diagnose Differentiation Various Forms of Cutaneous Leishmaniasis: A Comparative Study with Histopathology Open
objective: Histopathological studies suggest that parasite load is different between acute and chronic forms of cutaneous leishmaniasis (CL). However, highly sensitive detection methods are still needed to distinguish different forms of le…
View article: Peripheral Blood-Derived Mesenchymal Stem Cells: Growth Factor-Free Isolation, Molecular Characterization and Differentiation.
Peripheral Blood-Derived Mesenchymal Stem Cells: Growth Factor-Free Isolation, Molecular Characterization and Differentiation. Open
In spite of the absence of any stimulating factor, the cells adhered to the flasks and developed a rather homogeneous, spindle-shaped morphology after consecutive passages. The cells were confirmed to have mesenchymal phenotype by expressi…
View article: Commentary: Acute Myocardial Response to Stretch: What We (don't) Know
Commentary: Acute Myocardial Response to Stretch: What We (don't) Know Open
GENERAL COMMENTARY article Front. Physiol., 02 March 2017Sec. Striated Muscle Physiology Volume 8 - 2017 | https://doi.org/10.3389/fphys.2017.00121
View article: Erratum: The anti-inflammatory properties of Satureja khuzistanica Jamzad essential oil attenuate the effects of traumatic brain injuries in rats
Erratum: The anti-inflammatory properties of Satureja khuzistanica Jamzad essential oil attenuate the effects of traumatic brain injuries in rats Open
View article: The anti-inflammatory properties of Satureja khuzistanica Jamzad essential oil attenuate the effects of traumatic brain injuries in rats
The anti-inflammatory properties of Satureja khuzistanica Jamzad essential oil attenuate the effects of traumatic brain injuries in rats Open
Traumatic brain injury (TBI) is a major health concern affecting the general public as well as military personnel. However, there is no FDA-approved therapy for the treatment of TBIs. In this work, we investigated the neurotherapeutic effe…