Rhodri Saunders
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View article: Economic Impact Model of Incorporating Cxbladder Monitor in the Surveillance of Nonmuscle Invasive Bladder Cancer
Economic Impact Model of Incorporating Cxbladder Monitor in the Surveillance of Nonmuscle Invasive Bladder Cancer Open
Introduction: Guideline recommended surveillance of nonmuscle invasive bladder cancer (NMIBC) involves frequent cystoscopies. Cxbladder Monitor (CxbM) is a noninvasive urinary genomic test with high negative predictive value for NMIBC recu…
View article: Intrarenal Pressure Monitoring During Ureteroscopy: A Delphi Panel Consensus
Intrarenal Pressure Monitoring During Ureteroscopy: A Delphi Panel Consensus Open
A group of experts were asked their opinion on pressure within the kidney (intrarenal pressure, IRP) during a procedure called ureteroscopy (URS), when a narrow telescope is passed through the bladder and into the tube connected to the kid…
View article: The burden of venous thromboembolism in ten countries: a cost-of-illness Markov model on surgical and ICU patients
The burden of venous thromboembolism in ten countries: a cost-of-illness Markov model on surgical and ICU patients Open
The burden of hospital-acquired VTE is substantial both from an economic and from a patient perspective in all countries evaluated.
View article: Validation of a Model Estimating the Budget Impact of Video Capsule Endoscopy for Surveillance of Crohn’s Disease in an Italian Center
Validation of a Model Estimating the Budget Impact of Video Capsule Endoscopy for Surveillance of Crohn’s Disease in an Italian Center Open
Background: Crohn’s disease is a chronic ailment affecting the gastrointestinal tract. Mucosal healing, a marker of reduced disease activity, is currently assessed in the colonic sections using ileocolonoscopy and magnetic resonance entero…
View article: Validation of a Model Estimating the Budget Impact of Video Capsule Endoscopy for Surveillance of Crohn’s Disease in an Italian Center
Validation of a Model Estimating the Budget Impact of Video Capsule Endoscopy for Surveillance of Crohn’s Disease in an Italian Center Open
Background Crohn’s disease is a chronic ailment affecting the gastrointestinal tract. Mucosal healing, a marker of reduced disease activity, is currently assessed in the colonic sections using ileocolonoscopy and magnetic resonance enteros…
View article: Efficacy and safety of V-Loc™ barbed sutures versus conventional suture techniques in gynecological surgery: a systematic review and meta-analysis
Efficacy and safety of V-Loc™ barbed sutures versus conventional suture techniques in gynecological surgery: a systematic review and meta-analysis Open
View article: A Health Economic Analysis Exploring the Cost Consequence of Using a Surgical Site Infection Prevention Bundle for Hip and Knee Arthroplasty in Germany
A Health Economic Analysis Exploring the Cost Consequence of Using a Surgical Site Infection Prevention Bundle for Hip and Knee Arthroplasty in Germany Open
Background According to the European Centre for Disease Prevention and Control, surgical site infections (SSIs) constitute over 50% of all hospital-acquired infections. Reducing SSIs can enhance healthcare efficiency. Objective This study …
View article: A Health Economic Analysis Exploring the Cost Consequence of Using a Surgical Site Infection Prevention Bundle for Hip and Knee Arthroplasty in Germany
A Health Economic Analysis Exploring the Cost Consequence of Using a Surgical Site Infection Prevention Bundle for Hip and Knee Arthroplasty in Germany Open
Background: According to the European Centre for Disease Prevention and Control, surgical site infections (SSIs) constitute over 50% of all hospital-acquired infections. Reducing SSIs can enhance healthcare efficiency. Objective: This stud…
View article: Patient Safety during Propofol Sedation before and after Implementation of Capnography Monitoring
Patient Safety during Propofol Sedation before and after Implementation of Capnography Monitoring Open
Endoscopic procedures are routinely applied to cancer screening programs and surveillance. The preferred technique is usually deep sedation with propofol being a convenient agent allowing for a quicker patient recovery while maintaining a …
View article: Evaluating the Environmental Impact of Single-Use and Multi-Use Surgical Staplers with Staple Line Buttressing in Laparoscopic Bariatric Surgery
Evaluating the Environmental Impact of Single-Use and Multi-Use Surgical Staplers with Staple Line Buttressing in Laparoscopic Bariatric Surgery Open
The environmental impact of surgery can be greatly reduced by using MUS with pre-attached buttressing rather than SUS with separate buttressing.
View article: Cost-effectiveness of mechanical thromboprophylaxis for cesarean deliveries in Brazil
Cost-effectiveness of mechanical thromboprophylaxis for cesarean deliveries in Brazil Open
Objective To evaluate the cost-effectiveness of using mechanical thromboprophylaxis for patients undergoing a cesarean delivery in Brazil. Methods A decision-analytic model built in TreeAge software was used to compare the cost and effecti…
View article: Fast In-House Next-Generation Sequencing in the Diagnosis of Metastatic Non-small Cell Lung Cancer: A Hospital Budget Impact Analysis
Fast In-House Next-Generation Sequencing in the Diagnosis of Metastatic Non-small Cell Lung Cancer: A Hospital Budget Impact Analysis Open
Background Targeted therapy for cancer is becoming more frequent as the understanding of the molecular pathogenesis increases. Molecular testing must be done to use targeted therapy. Unfortunately, the testing turnaround time can delay the…
View article: Fast In-House Next-Generation Sequencing in the Diagnosis of Metastatic Non-small Cell Lung Cancer: A Hospital Budget Impact Analysis
Fast In-House Next-Generation Sequencing in the Diagnosis of Metastatic Non-small Cell Lung Cancer: A Hospital Budget Impact Analysis Open
Background: Targeted therapy for cancer is becoming more frequent as the understanding of the molecular pathogenesis increases. Molecular testing must be done to use targeted therapy. Unfortunately, the testing turnaround time can delay th…
View article: A single-patient-use ECG system for cardiothoracic surgery admissions in the UK: A cost-consequence analysis
A single-patient-use ECG system for cardiothoracic surgery admissions in the UK: A cost-consequence analysis Open
Background Deep sternal wound infections (DSWI) are severe complications in up to 1.36% of coronary artery bypass grafting (CABG) procedures in the United Kingdom. Each event adds between £4,000 and £11,000 in healthcare costs, owing prima…
View article: PP150 The Role Of Expert Consensus In UK Guidance: Patient Selection For Hydrogel Spacer Use During Prostate Cancer Radiotherapy
PP150 The Role Of Expert Consensus In UK Guidance: Patient Selection For Hydrogel Spacer Use During Prostate Cancer Radiotherapy Open
Introduction In UK males, prostate cancer is the most common cancer, with over 47,500 diagnosed annually. Radiotherapy is a highly effective curative treatment but can be limited by dose to surrounding normal-tissues such as the rectum. Ra…
View article: PP34 Next Generation Sequencing For Informing Lung Cancer Therapy In Europe – Hospital Impact With A Lifecycle Perspective
PP34 Next Generation Sequencing For Informing Lung Cancer Therapy In Europe – Hospital Impact With A Lifecycle Perspective Open
Introduction Next-generation sequencing (NGS) can be run in-house or outsourced to an independent laboratory. It has enabled wider use of deoxyribonucleic acid/ribonucleic acid (DNA + RNA) sequencing in clinical practice. Within oncology, …
View article: Capsule endoscopy in Crohn's disease surveillance: A monocentric, retrospective analysis in Italy
Capsule endoscopy in Crohn's disease surveillance: A monocentric, retrospective analysis in Italy Open
Background Crohn's disease (CD) is a potentially debilitating condition that burdens Italian healthcare substantially. The symptomatic management relies on prompt therapy adjustment to reduce flares and follow-up diagnostic inputs to maxim…
View article: Cancer patient management: Current use of next-generation sequencing in the EU TOP4
Cancer patient management: Current use of next-generation sequencing in the EU TOP4 Open
The evident information gap between involved parties and demand for consistent national guidelines could be filled by health economics analyses tailored to local specifics to provide factual leverage for a structured adoption of NGS testin…
View article: Moving preinduction cervical ripening to a lower acuity inpatient setting using the synthetic hygroscopic cervical dilator: a cost-consequence analysis for the United States
Moving preinduction cervical ripening to a lower acuity inpatient setting using the synthetic hygroscopic cervical dilator: a cost-consequence analysis for the United States Open
In this theoretical study, implementing a ripening room using SHCDs resulted in the lowest time burden and the second lowest costs. The cheapest option for preinduction cervical ripening was vaginal misoprostol.
View article: Synthetic osmotic dilators (Dilapan-S) or dinoprostone vaginal inserts (Propess) for inpatient induction of labour: A UK cost-consequence model
Synthetic osmotic dilators (Dilapan-S) or dinoprostone vaginal inserts (Propess) for inpatient induction of labour: A UK cost-consequence model Open
View article: Corrigendum: Service evaluation of the impact of capnography on the safety of procedural sedation
Corrigendum: Service evaluation of the impact of capnography on the safety of procedural sedation Open
[This corrects the article DOI: 10.3389/fmed.2022.867536.].
View article: Delphi study to identify consensus on patient selection for hydrogel rectal spacer use during radiation therapy for prostate cancer in the UK
Delphi study to identify consensus on patient selection for hydrogel rectal spacer use during radiation therapy for prostate cancer in the UK Open
Objectives To identify consensus on patient prioritisation for rectal hydrogel spacer use during radiation therapy for the treatment of prostate cancer in the UK. Design Delphi study consisting of two rounds of online questionnaires, two v…
View article: EE225 Economic and Clinical Impact of a Novel, Antiviral Therapy on COVID-19 in the US
EE225 Economic and Clinical Impact of a Novel, Antiviral Therapy on COVID-19 in the US Open
View article: Service Evaluation of the Impact of Capnography on the Safety of Procedural Sedation
Service Evaluation of the Impact of Capnography on the Safety of Procedural Sedation Open
Background Capnography has been associated with a reduced incidence of events related to respiratory compromise during procedural sedation. Methods A prospective service evaluation was conducted at a large United Kingdom (UK) teaching hosp…
View article: Economic and clinical impact of a novel, light-based, at-home antiviral treatment on mild-to-moderate COVID-19
Economic and clinical impact of a novel, light-based, at-home antiviral treatment on mild-to-moderate COVID-19 Open
At-home, antiviral treatment with RD-X19 or other interventions with similar efficacy that decrease both symptomatic days and transmission probabilities can be used in concert with vaccines to reduce COVID-19 cases, deaths, and direct heal…
View article: Proportional-assist ventilation with load-adjustable gain factors for mechanical ventilation: a cost-utility analysis
Proportional-assist ventilation with load-adjustable gain factors for mechanical ventilation: a cost-utility analysis Open
Use of PAV+ mode is expected to benefit patient care in the intensive care unit (ICU) and be a cost-effective alternative to PSV in the Canadian setting. Canadian hospital payers may therefore consider how best to optimally deliver mechani…
View article: PP290 Ongoing Swedish Initiatives To Improve The Potential For Real World Data Assessment Of Medical Devices
PP290 Ongoing Swedish Initiatives To Improve The Potential For Real World Data Assessment Of Medical Devices Open
Introduction In 2020, the Swedish regions cemented a national managed-introduction project for medical devices, to ensure equal, cost-effective, and appropriate use. Health technology assessment (HTA) is an important component of the proje…
View article: PP275 Incorporating Quality-Of-Care Indicators In Health Economic Modelling: A Case-Study On Surgical Site Infections In Cardiac Surgery
PP275 Incorporating Quality-Of-Care Indicators In Health Economic Modelling: A Case-Study On Surgical Site Infections In Cardiac Surgery Open
Introduction Surgical site infections (SSIs) are preventable adverse events placing a large burden on service providers. Reusable electrocardiogram lead-and-wire systems can hold infection vectors after cleaning. Single-patient-use cable-a…
View article: PP205 The Use Of Real-World Evidence To Support National Institute For Health And Care Excellence Medical Technology Submissions
PP205 The Use Of Real-World Evidence To Support National Institute For Health And Care Excellence Medical Technology Submissions Open
Introduction Although randomized controlled trials (RCTs) are recognized as providing the highest level of clinical evidence, few medical device RCTs are available due to underfunding or inherent challenges associated with trial design. Th…
View article: PP206 Health Technology Assessment Guidance In The United Kingdom: Addressing Issues Specific To Medical Devices
PP206 Health Technology Assessment Guidance In The United Kingdom: Addressing Issues Specific To Medical Devices Open
Introduction The United Kingdom spends approximately GBP4.2 billion (USD5.6 billion; EUR4.7 billion) each year on medical devices, but healthcare providers receive little health technology assessment (HTA) guidance on cost-effective device…