Ricardo Ney Cobucci
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View article: Uso do ácido acetilsalicílico, expressão de marcadores da pré-eclâmpsia e doppler de artérias uterinas no segundo trimestre gestacional
Uso do ácido acetilsalicílico, expressão de marcadores da pré-eclâmpsia e doppler de artérias uterinas no segundo trimestre gestacional Open
A pré-eclâmpsia (PE) ocorre na gestação com hipertensão e proteinúria e está associada com morbimortalidade materna e fetal. Na fisiopatologia ocorre uma disfunção inflamatória vascular e placentária, alterando marcadores séricos e biofísi…
View article: Segurança do paciente e tecnologia: uma revisão narrativa das principais inovações na última década
Segurança do paciente e tecnologia: uma revisão narrativa das principais inovações na última década Open
Objectives: To review technologies aimed at patient safety over the last decade, identifying their impact on error reduction and care quality. Methods: Narrative review with searches in PubMed and Google Scholar, including studies in Portu…
View article: Association Between Maternal Diet and Frequency of Micronuclei in Mothers and Newborns: A Systematic Review
Association Between Maternal Diet and Frequency of Micronuclei in Mothers and Newborns: A Systematic Review Open
Background/Objectives: The effect of diet on maternal and infant genetic levels has been reported in the literature. Diet-associated DNA damage, such as the presence of micronuclei (MN), may be related to an increased risk of developing ch…
View article: Genetic association between <scp>microRNA</scp> gene polymorphisms and polycystic ovary syndrome susceptibility: A systematic review and meta‐analysis
Genetic association between <span>microRNA</span> gene polymorphisms and polycystic ovary syndrome susceptibility: A systematic review and meta‐analysis Open
Background Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in women of reproductive age, associated with genetic and environmental factors, including microRNA (miRNA) gene polymorphisms. Objective To evaluate the associa…
View article: Apoptosis and G2/M Phase Cell Cycle Arrest Induced by Alkaloid Erythraline Isolated from Erythrina velutina in SiHa Cervical Cancer Cell
Apoptosis and G2/M Phase Cell Cycle Arrest Induced by Alkaloid Erythraline Isolated from Erythrina velutina in SiHa Cervical Cancer Cell Open
Cervical cancer remains a significant global health concern, causing more than 300,000 deaths annually. Erythrina velutina, a tree native to north-eastern Brazil, contains bioactive alkaloids with potential anticancer properties. This stud…
View article: Exosomal MicroRNAs as Epigenetic Biomarkers for Endometriosis: A Systematic Review and Bioinformatics Analysis
Exosomal MicroRNAs as Epigenetic Biomarkers for Endometriosis: A Systematic Review and Bioinformatics Analysis Open
The clinical application of exosomal microRNAs as diagnostic biomarkers presents a promising approach for identifying potential markers of endometriosis. We conducted a systematic review of case–control studies to investigate exosomal micr…
View article: AVALIAÇÃO DO ASSOALHO PÉLVICO DE GESTANTES E PUÉRPERAS ATRAVÉS DA ULTRASONOGRAFIA TRANSPERINEAL E DA ELETROMIOGRAFIA DE SUPERFÍCIE: UMA REVISÃO DE LITERATURA
AVALIAÇÃO DO ASSOALHO PÉLVICO DE GESTANTES E PUÉRPERAS ATRAVÉS DA ULTRASONOGRAFIA TRANSPERINEAL E DA ELETROMIOGRAFIA DE SUPERFÍCIE: UMA REVISÃO DE LITERATURA Open
View article: DESENVOLVIMENTO DE SITE PARA ACOLHIMENTO MULTIDISCIPLINAR E ATENDIMENTO INTEGRAL A MULHERES VÍTIMAS DE VIOLÊNCIA SEXUAL
DESENVOLVIMENTO DE SITE PARA ACOLHIMENTO MULTIDISCIPLINAR E ATENDIMENTO INTEGRAL A MULHERES VÍTIMAS DE VIOLÊNCIA SEXUAL Open
View article: Homozygous AA Genotype of IL-17A and 14-bp Insertion Polymorphism in HLA-G 3′UTR Are Associated with Increased Risk of Gestational Diabetes Mellitus
Homozygous AA Genotype of IL-17A and 14-bp Insertion Polymorphism in HLA-G 3′UTR Are Associated with Increased Risk of Gestational Diabetes Mellitus Open
Gestational diabetes mellitus (GDM) is a common pregnancy complication characterized by hyperglycemia and insulin resistance, with unclear genetic mechanisms. The specific involvement of proinflammatory cytokines, including IL-17A, and the…
View article: Protecting the next generation: how maternal Respiratory Syncytial Virus (RSV) vaccination during pregnancy safeguards child health
Protecting the next generation: how maternal Respiratory Syncytial Virus (RSV) vaccination during pregnancy safeguards child health Open
View article: Efficacy and safety of pembrolizumab in cervical cancer: Protocol for systematic review and meta-analysis of randomized clinical trials
Efficacy and safety of pembrolizumab in cervical cancer: Protocol for systematic review and meta-analysis of randomized clinical trials Open
Purpose This paper reports a systematic review and meta-analysis protocol that will be used to evaluate the efficacy and safety of pembrolizumab, alone or combined with bevacizumab and other therapies, in adult women with cervical carcinom…
View article: BECHECK: DESENVOLVIMENTO DE TECNOLOGIA PARA APOIAR ASSISTÊNCIA EM PERINATOLOGIA
BECHECK: DESENVOLVIMENTO DE TECNOLOGIA PARA APOIAR ASSISTÊNCIA EM PERINATOLOGIA Open
View article: Correction: Effect of maternal diet on the frequency of micronuclei in pregnant women and newborns: A protocol for systematic review and meta-analysis
Correction: Effect of maternal diet on the frequency of micronuclei in pregnant women and newborns: A protocol for systematic review and meta-analysis Open
[This corrects the article DOI: 10.1371/journal.pone.0300714.].
View article: Effect of maternal diet on the frequency of micronuclei in pregnant women and newborns: A protocol for systematic review and meta-analysis
Effect of maternal diet on the frequency of micronuclei in pregnant women and newborns: A protocol for systematic review and meta-analysis Open
Background The effects of diet on maternal and child genetic levels have been previously reported. Diet-associated DNA damage, such as the presence of micronuclei (MN), may be related to an increased risk of developing chronic diseases, su…
View article: DESENVOLVIMENTO DE APP MHEALTH (RN PHOTOINDICATOR) PARA IDENTIFICAÇÃO DA NECESSIDADE DE FOTOTERAPIA EM NEONATOS COM ICTERÍCIA
DESENVOLVIMENTO DE APP MHEALTH (RN PHOTOINDICATOR) PARA IDENTIFICAÇÃO DA NECESSIDADE DE FOTOTERAPIA EM NEONATOS COM ICTERÍCIA Open
Phototherapy represents the primary treatment modality for jaundice in neonates, effectively reducing unconjugated bilirubin levels. The Neonatal Jaundice guideline, established by the National Institute for Health and Care Excellence (NIC…
View article: Effects of vitamin D supplementation on cardiometabolic parameters among patients with metabolic syndrome: A systematic review and GRADE evidence synthesis of randomized controlled trials
Effects of vitamin D supplementation on cardiometabolic parameters among patients with metabolic syndrome: A systematic review and GRADE evidence synthesis of randomized controlled trials Open
View article: Abusive use of Zolpidem as a Result of COVID-19 and Perspectives ofContinuity of the Problem in the Post-Pandemic Period
Abusive use of Zolpidem as a Result of COVID-19 and Perspectives ofContinuity of the Problem in the Post-Pandemic Period Open
Zolpidem is a non-benzodiazepine hypnotic drug that works as a positive modulator of Gamma-Amino Butyric Acid-A (GABA-A) receptors, with high selectivity for α1 subunits. Given this selective binding, the drug has a strong hypnotic activit…
View article: Conhecimento e utilização de metodologias ativas de ensino e matriz de competência por preceptores de residência médica
Conhecimento e utilização de metodologias ativas de ensino e matriz de competência por preceptores de residência médica Open
Introdução: Apesar de já existirem 46 matrizes de competência em diferentes especialidades aprovadas pela comissão nacional de residência médica, e desde 2014 as diretrizes curriculares nacionais já preconizarem a utilização das metodologi…
View article: A-336 Comparison Between the Immune Profile of Pregnant and Postpartum Women with and without COVID-19 by Flow Cytometry
A-336 Comparison Between the Immune Profile of Pregnant and Postpartum Women with and without COVID-19 by Flow Cytometry Open
Background The impacts caused by COVID-19 on pregnant and postpartum women are not well characterized yet. It is well known that, due to pregnancy, the maternal organism undergoes immunological adaptations, which may increase the risk of c…
View article: BJN volume 130 issue 4 Cover and Back matter
BJN volume 130 issue 4 Cover and Back matter Open
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View article: Vitamin E and Its Molecular Effects in Experimental Models of Neurodegenerative Diseases
Vitamin E and Its Molecular Effects in Experimental Models of Neurodegenerative Diseases Open
With the advancement of in vivo studies and clinical trials, the pathogenesis of neurodegenerative diseases has been better understood. However, gaps still need to be better elucidated, which justifies the publication of reviews that explo…
View article: Uma análise do feminino na contemporaneidade a partir da psicanálise
Uma análise do feminino na contemporaneidade a partir da psicanálise Open
Diferentemente de Freud, que considerava a maternidade a forma mais elaborada de desfecho do complexo de Édipo na mulher, para Lacan, ser mãe não bastava para que o ser do sexo feminino encontrasse uma posição enquanto mulher na sexuação, …
View article: Impact of overweight and obesity on disease activity and remission in systemic lupus erythematosus: A systematic review and meta-analysis protocol
Impact of overweight and obesity on disease activity and remission in systemic lupus erythematosus: A systematic review and meta-analysis protocol Open
Background Systemic lupus erythematosus (SLE) is an autoimmune and inflammatory disease that requires treatment with hydroxychloroquine and glucocorticoids. Glucocorticoids are responsible for adverse effects such as increased weight, whic…
View article: Estudo de usabilidade de aplicativo móvel para diagnóstico da endometriose
Estudo de usabilidade de aplicativo móvel para diagnóstico da endometriose Open
Objetivos: Avaliar a usabilidade entre médicos de um aplicativo móvel, Endometriosis Intelligent Application (ENIA), criado para facilitar o diagnóstico da endometriose. Métodos: O estudo envolveu 15 médicos especialistas e 21 residentes e…
View article: Home-Based Indoor Physical Activity Programs for Community-Dwelling Older Adults: A Systematic Review
Home-Based Indoor Physical Activity Programs for Community-Dwelling Older Adults: A Systematic Review Open
Context: Home-based exercise programs are a good strategy to promote benefits to health for people who cannot visit gyms, clinics, or have limited time for physical activity outside. Objective: To synthesize the effect of home-based indoor…
View article: Neuroprotective Potential of Seed Extracts: Review of In Vitro and In Vivo Studies
Neuroprotective Potential of Seed Extracts: Review of In Vitro and In Vivo Studies Open
Introduction: Neurodegenerative diseases are characterized by neuronal dysfunction and death. Studies suggest that some seed extracts have a neuroprotective effect. Considering the increased incidence of these diseases and the need for new…
View article: SISTEMA ACGEST PARA ASSISTÊNCIA À SAÚDE DE GESTANTES E PUÉRPERAS NA ATENÇÃO PRIMÁRIA
SISTEMA ACGEST PARA ASSISTÊNCIA À SAÚDE DE GESTANTES E PUÉRPERAS NA ATENÇÃO PRIMÁRIA Open
Ensuring quality prenatal and puerperal care is one of the public health policies in Brazil aimed at women and developed by nurses and community health agents (CHA) in primary care. Technology can improve the work process of these teams by…
View article: Image-guided endoscopic sinus surgery for patients with chronic rhinosinusitis: a systematic review and meta-analysis
Image-guided endoscopic sinus surgery for patients with chronic rhinosinusitis: a systematic review and meta-analysis Open
Objective: The aim of this study was to compare the quality of life and complications of endoscopic sinus surgery, with and without image guidance, in patients with chronic rhinosinusitis. Design and setting: Systematic review and meta-ana…
View article: Vitamin E Levels in Preterm and Full-Term Infants: A Systematic Review
Vitamin E Levels in Preterm and Full-Term Infants: A Systematic Review Open
Vitamin E deficiency (VED) is associated with clinical repercussions in preterm newborns (PTN), but low levels are also found in full-term newborns (TN). As this inadequacy can compromise neurogenesis in childhood, studies are needed to as…
View article: Effects of selenium supplementation on glycemic control markers in healthy rodents: A systematic review protocol
Effects of selenium supplementation on glycemic control markers in healthy rodents: A systematic review protocol Open
Background In vivo and in vitro studies have shown that Se has an insulin-mimetic action associated with its antioxidant activity. Other studies, in turn, suggest that high Se doses and high selenoprotein expression interfere with insulin …