Richa Pant
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View article: Artificial intelligence as a proficient tool in detecting pulmonary tuberculosis in massive population screening programs: a case study in Chennai, India
Artificial intelligence as a proficient tool in detecting pulmonary tuberculosis in massive population screening programs: a case study in Chennai, India Open
Genki demonstrated excellent value as a TB screening tool in remote locations in Chennai, India. Employing a CADe-based approach for systematic TB screening is cost-effective and reduces workload in high-burden and low-resource settings.
View article: Validation of a Deep Learning Model for Detecting Chest Pathologies from Digital Chest Radiographs
Validation of a Deep Learning Model for Detecting Chest Pathologies from Digital Chest Radiographs Open
Purpose: Manual interpretation of chest radiographs is a challenging task and is prone to errors. An automated system capable of categorizing chest radiographs based on the pathologies identified could aid in the timely and efficient diagn…
View article: Automated assessment of chest CT severity scores in patients suspected of COVID-19 infection
Automated assessment of chest CT severity scores in patients suspected of COVID-19 infection Open
Background The COVID-19 pandemic has claimed numerous lives in the last three years. With new variants emerging every now and then, the world is still battling with the management of COVID-19. Purpose To utilize a deep learning model for t…
View article: A deep learning approach for automated diagnosis of pulmonary embolism on computed tomographic pulmonary angiography
A deep learning approach for automated diagnosis of pulmonary embolism on computed tomographic pulmonary angiography Open
View article: Levels of Autonomous Radiology
Levels of Autonomous Radiology Open
Radiology, being one of the younger disciplines of medicine with a history of just over a century, has witnessed tremendous technological advancements and has revolutionized the way we practice medicine today. In the last few decades, medi…
View article: A deep learning approach for automated diagnosis of pulmonary embolism on computed tomographic pulmonary angiography
A deep learning approach for automated diagnosis of pulmonary embolism on computed tomographic pulmonary angiography Open
Background Computed tomographic pulmonary angiography (CTPA) is the diagnostic standard for confirming Pulmonary Embolism (PE). Since PE is a life-threatening condition, early diagnosis and treatment are critical to avoid PE-associated mor…
View article: Deep-learning-based automatic detection of pulmonary nodules from chest radiographs
Deep-learning-based automatic detection of pulmonary nodules from chest radiographs Open
Background Most early lung cancers appear as pulmonary nodules on medical imaging, however, radiologists frequently overlook these on chest radiographs. We assessed if a deep learning-based artificial intelligence model can help detect pul…
View article: Observer performance evaluation of the feasibility of a deep learning model to detect cardiomegaly on chest radiographs
Observer performance evaluation of the feasibility of a deep learning model to detect cardiomegaly on chest radiographs Open
Background Cardiothoracic ratio (CTR) is the ratio of the diameter of the heart to the diameter of the thorax. An abnormal CTR (>0.55) is often an indicator of an underlying pathological condition. The accurate prediction of an abnormal CT…
View article: Deep-learning-based automatic detection of pulmonary nodules from chest radiographs
Deep-learning-based automatic detection of pulmonary nodules from chest radiographs Open
Objective To assess a deep learning-based artificial intelligence model for the detection of pulmonary nodules on chest radiographs and to compare its performance with board-certified human readers. Methods For this retrospective study, 30…
View article: Validation of a Deep Learning Model to aid in COVID-19 Detection from Digital Chest Radiographs
Validation of a Deep Learning Model to aid in COVID-19 Detection from Digital Chest Radiographs Open
Introduction Using artificial intelligence in imaging practice helps ensure study list reprioritization, prompt attention to urgent studies, and reduces the reporting turn-around time. Purpose We tested a deep learning-based artificial int…
View article: Levels of Autonomous Radiology (Preprint)
Levels of Autonomous Radiology (Preprint) Open
UNSTRUCTURED Radiology, being one of the younger disciplines of medicine with a history of just over a century, has witnessed tremendous technological advancements and has revolutionized the way we practice medicine today. In the last few…
View article: RING finger protein TOPORS modulates the expression of tumor suppressor <i>SMAR1</i> in colorectal cancer via the TLR4‐TRIF pathway
RING finger protein TOPORS modulates the expression of tumor suppressor <i>SMAR1</i> in colorectal cancer via the TLR4‐TRIF pathway Open
TOP1‐binding arginine/serine‐rich protein (TOPORS), a really interesting new gene finger protein, has the ability to bind to a palindromic consensus DNA sequence that enables it to function as a potential transcriptional regulator. However…
View article: An artificial intelligence system for predicting mortality in COVID-19 patients using chest X-rays: a retrospective study
An artificial intelligence system for predicting mortality in COVID-19 patients using chest X-rays: a retrospective study Open
Background Early prediction of disease severity in COVID-19 patients is essential. Chest X-ray (CXR) is a faster, widely available, and less expensive imaging modality that may be useful in predicting mortality in COVID-19 patients. Artifi…
View article: Tumor suppressor SMAR1 regulates PKM alternative splicing by HDAC6-mediated deacetylation of PTBP1
Tumor suppressor SMAR1 regulates PKM alternative splicing by HDAC6-mediated deacetylation of PTBP1 Open
View article: Tumor Suppressor SMAR1 Regulates PKM Alternative Splicing by HDAC6 Mediated Deacetylation of PTBP1
Tumor Suppressor SMAR1 Regulates PKM Alternative Splicing by HDAC6 Mediated Deacetylation of PTBP1 Open
Background:Highly proliferating cancer cells exhibit the Warburg effect by regulation of PKM alternative splicing and promoting the expression of PKM2. Majority of the alternative splicing events are known to occur in the nuclear matrix wh…
View article: Epigenetic Regulation of Adipogenesis in Development of Metabolic Syndrome
Epigenetic Regulation of Adipogenesis in Development of Metabolic Syndrome Open
Obesity is one of the biggest public health concerns identified by an increase in adipose tissue mass as a result of adipocyte hypertrophy and hyperplasia. Pertaining to the importance of adipose tissue in various biological processes, any…
View article: Wnt Signaling and Its Significance Within the Tumor Microenvironment: Novel Therapeutic Insights
Wnt Signaling and Its Significance Within the Tumor Microenvironment: Novel Therapeutic Insights Open
Wnt signaling is one of the central mechanisms regulating tissue morphogenesis during embryogenesis and repair. The pivot of this signaling cascade is the Wnt ligand, which binds to receptors belonging to the Frizzled family or the ROR1/RO…
View article: SMAR1 favors immunosurveillance of cancer cells by modulating calnexin and MHC I expression
SMAR1 favors immunosurveillance of cancer cells by modulating calnexin and MHC I expression Open
Down-regulation or loss of MHC class I expression is a major mechanism used by cancer cells to evade immunosurveillance and increase their oncogenic potential. MHC I mediated antigen presentation is a complex regulatory process, controlled…