Richard A. Forsgård
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View article: Acute effects of butyrate on intestinal permeability in patients with irritable bowel syndrome assessed by a novel colonoscopy research model.
Acute effects of butyrate on intestinal permeability in patients with irritable bowel syndrome assessed by a novel colonoscopy research model. Open
Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder for which effective treatment strategies are insufficient. Butyrate, a microbiota-derived short-chain fatty acid believed to strengthen the intestinal barrier function…
View article: The effects of a 6-week intervention with Limosilactobacillus reuteri ATCC PTA 6475 alone and in combination with L. reuteri DSM 17938 on gut barrier function, immune markers, and symptoms in patients with IBS-D—An exploratory RCT
The effects of a 6-week intervention with Limosilactobacillus reuteri ATCC PTA 6475 alone and in combination with L. reuteri DSM 17938 on gut barrier function, immune markers, and symptoms in patients with IBS-D—An exploratory RCT Open
Background An increased intestinal permeability is a common feature in patients with diarrhoea-predominant irritable bowel syndrome (IBS-D). Probiotics have shown to improve IBS symptoms and might also affect intestinal barrier function. A…
View article: Butyrate-promoting fibers improves fasting plasma glucose levels in subjects with prediabetes – A randomized, double-blinded, placebo-controlled crossover study
Butyrate-promoting fibers improves fasting plasma glucose levels in subjects with prediabetes – A randomized, double-blinded, placebo-controlled crossover study Open
View article: The effects of a 6-week probiotic intervention on gut barrier function, immune markers and symptoms in patients with irritable bowel syndrome
The effects of a 6-week probiotic intervention on gut barrier function, immune markers and symptoms in patients with irritable bowel syndrome Open
View article: The Effects of Fermentable Dietary Fibre Supplementation on Intestinal Barrier Function, Intestinal Microbiome, and Inflammation in Microscopic Colitis Patients—A Randomised, Triple-Blinded, Placebo-Controlled Trial
The Effects of Fermentable Dietary Fibre Supplementation on Intestinal Barrier Function, Intestinal Microbiome, and Inflammation in Microscopic Colitis Patients—A Randomised, Triple-Blinded, Placebo-Controlled Trial Open
Background: Microscopic colitis (MC) is a chronic inflammatory disease of the colon that primarily manifests as chronic watery diarrhoea. The aetiology of MC is still unknown, but the current hypothesis states that MC results from an abnor…
View article: Interindividual Variation in Gut Nitrergic Neuron Density Is Regulated By GDNF Levels and ETV1
Interindividual Variation in Gut Nitrergic Neuron Density Is Regulated By GDNF Levels and ETV1 Open
Our results reveal how normal variation in GDNF levels influence ENS size, composition, and gut function, suggesting a mechanism for well-known interindividual variation among those parameters.
View article: <i>Limosilactobacillus reuteri</i> DSM 17938 supplementation and SARS-CoV-2 specific antibody response in healthy adults: a randomized, triple-blinded, placebo-controlled trial
<i>Limosilactobacillus reuteri</i> DSM 17938 supplementation and SARS-CoV-2 specific antibody response in healthy adults: a randomized, triple-blinded, placebo-controlled trial Open
Studies have shown that probiotics can decrease the symptoms of respiratory tract infections as well as increase antibody responses following certain vaccinations. We examined the effect of probiotic supplementation on anti-SARS-CoV-2 spec…
View article: Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo
Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo Open
View article: Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague–Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles
Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague–Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles Open
View article: Lactose digestion in humans: intestinal lactase appears to be constitutive whereas the colonic microbiome is adaptable
Lactose digestion in humans: intestinal lactase appears to be constitutive whereas the colonic microbiome is adaptable Open
View article: Intestinal permeability as a marker of gastrointestinal health
Intestinal permeability as a marker of gastrointestinal health Open
Intestinal permeability is a key measure of gastrointestinal function and studies have associated increased intestinal permeability with several different pathologies. Clinically, increased intestinal permeability could contribute to disea…
View article: Exercise and gastrointestinal symptoms: running-induced changes in intestinal permeability and markers of gastrointestinal function in asymptomatic and symptomatic runners
Exercise and gastrointestinal symptoms: running-induced changes in intestinal permeability and markers of gastrointestinal function in asymptomatic and symptomatic runners Open
View article: Chemotherapy-induced gastrointestinal toxicity is associated with changes in serum and urine metabolome and fecal microbiota in male Sprague–Dawley rats
Chemotherapy-induced gastrointestinal toxicity is associated with changes in serum and urine metabolome and fecal microbiota in male Sprague–Dawley rats Open
View article: Intestinal permeability to iohexol as an in vivo marker of chemotherapy-induced gastrointestinal toxicity in Sprague–Dawley rats
Intestinal permeability to iohexol as an in vivo marker of chemotherapy-induced gastrointestinal toxicity in Sprague–Dawley rats Open
Chemotherapeutic drugs, such as 5-fluorouracil, oxaliplatin, and irinotecan, increase intestinal permeability to iohexol. Measuring intestinal permeability to iohexol could provide a simple marker for assessing chemotherapy-induced gastroi…