Richard Anney
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View article: Author response: Relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis
Author response: Relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis Open
View article: The relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis
The relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis Open
Cognitive abilities are often linked to mental health across various disorders, a pattern observed even in childhood. However, the extent to which this relationship is represented by different neurobiological units of analysis, such as mul…
View article: Author response: The relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis
Author response: The relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis Open
View article: Relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis
Relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis Open
Cognitive abilities are closely tied to mental health from early childhood. This study explores how neurobiological units of analysis of cognitive abilities—multimodal neuroimaging and polygenic scores (PGS)—represent this connection. Usin…
View article: The relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis
The relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis Open
Cognitive abilities are often associated with mental health across different disorders, beginning in childhood. However, the extent to which the relationship between cognitive abilities and mental health is represented in part by different…
View article: Common risk alleles for schizophrenia within the major histocompatibility complex predict white matter microstructure
Common risk alleles for schizophrenia within the major histocompatibility complex predict white matter microstructure Open
Recent research has highlighted the role of complement genes in shaping the microstructure of the brain during early development, and in contributing to common allele risk for Schizophrenia. We hypothesised that common risk variants for sc…
View article: The relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis
The relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis Open
Cognitive abilities are often linked to mental health across various disorders, a pattern observed even in childhood. However, the extent to which this relationship is represented by different neurobiological units of analysis, such as mul…
View article: Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression
Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression Open
While more samples are needed to reach genome-wide levels of significance, the results presented confirm PPD as a polygenic and heritable phenotype. There is also evidence that despite a high correlation with MDD, PPD may have unique genet…
View article: Corrigendum to “Characterising depression trajectories in young people at high familial risk of depression” [J. Affect. Disord. 337 (2023) 66–74 (15 September)]
Corrigendum to “Characterising depression trajectories in young people at high familial risk of depression” [J. Affect. Disord. 337 (2023) 66–74 (15 September)] Open
View article: Phenotypic effects of genetic variants associated with autism
Phenotypic effects of genetic variants associated with autism Open
View article: Common risk alleles for schizophrenia within the Major Histocompatibility Complex predict white matter microstructure
Common risk alleles for schizophrenia within the Major Histocompatibility Complex predict white matter microstructure Open
Recent research has highlighted the role of complement genes in shaping the microstructure of the brain during early development, and in contributing to common allele risk for Schizophrenia. We hypothesised that common risk variants for sc…
View article: Characterising depression trajectories in young people at high familial risk of depression
Characterising depression trajectories in young people at high familial risk of depression Open
View article: DRAGON-Data: a platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts
DRAGON-Data: a platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts Open
Background Current psychiatric diagnoses, although heritable, have not been clearly mapped onto distinct underlying pathogenic processes. The same symptoms often occur in multiple disorders, and a substantial proportion of both genetic and…
View article: Copy Number Variants Increasing Risk for Schizophrenia: Shared and Distinct Effects on Brain Morphometry and Cognitive Performance
Copy Number Variants Increasing Risk for Schizophrenia: Shared and Distinct Effects on Brain Morphometry and Cognitive Performance Open
View article: Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p
Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p Open
View article: Longitudinally stable, brain‐based predictive models mediate the relationships between childhood cognition and socio‐demographic, psychological and genetic factors
Longitudinally stable, brain‐based predictive models mediate the relationships between childhood cognition and socio‐demographic, psychological and genetic factors Open
Cognitive abilities are one of the major transdiagnostic domains in the National Institute of Mental Health's Research Domain Criteria (RDoC). Following RDoC's integrative approach, we aimed to develop brain‐based predictive models for cog…
View article: Investigating Direct and Indirect Genetic Effects in Attention-Deficit/Hyperactivity Disorder Using Parent-Offspring Trios
Investigating Direct and Indirect Genetic Effects in Attention-Deficit/Hyperactivity Disorder Using Parent-Offspring Trios Open
View article: Investigating direct and indirect genetic effects in attention deficit hyperactivity disorder (ADHD) using parent-offspring trios
Investigating direct and indirect genetic effects in attention deficit hyperactivity disorder (ADHD) using parent-offspring trios Open
Background Attention deficit hyperactivity disorder (ADHD) is highly heritable, but little is known about the relative effects of transmitted (i.e. direct) and non-transmitted (i.e. indirect) common variant risks. Using parent-offspring tr…
View article: Genetic common variants associated with cerebellar volume and their overlap with mental disorders: a study on 33,265 individuals from the UK-Biobank
Genetic common variants associated with cerebellar volume and their overlap with mental disorders: a study on 33,265 individuals from the UK-Biobank Open
View article: DRAGON-Data: A platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts
DRAGON-Data: A platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts Open
Introduction Current psychiatric diagnoses, although heritable, have not been clearly mapped onto distinct underlying pathogenic processes. The same symptoms often occur in multiple disorders, and a substantial proportion of both genetic a…
View article: Sleep disturbances in ADHD: investigating the contribution of polygenic liability for ADHD and sleep-related phenotypes
Sleep disturbances in ADHD: investigating the contribution of polygenic liability for ADHD and sleep-related phenotypes Open
Sleep disturbances are common in attention deficit hyperactivity disorder (ADHD) and associated with poor outcomes. We tested whether, in children with ADHD, (1) polygenic liability for sleep phenotypes is over- or under-transmitted from p…
View article: The antecedents and outcomes of persistent and remitting adolescent depressive symptom trajectories: a longitudinal, population-based English study
The antecedents and outcomes of persistent and remitting adolescent depressive symptom trajectories: a longitudinal, population-based English study Open
View article: Motivation and Cognitive Abilities as Mediators Between Polygenic Scores and Psychopathology in Children
Motivation and Cognitive Abilities as Mediators Between Polygenic Scores and Psychopathology in Children Open
View article: Investigating regions of shared genetic variation in attention deficit/hyperactivity disorder and major depressive disorder: a GWAS meta-analysis
Investigating regions of shared genetic variation in attention deficit/hyperactivity disorder and major depressive disorder: a GWAS meta-analysis Open
View article: Longitudinally stable, brain-based predictive models mediate the relationships between childhood cognition and socio-demographic, psychological and genetic factors
Longitudinally stable, brain-based predictive models mediate the relationships between childhood cognition and socio-demographic, psychological and genetic factors Open
Cognitive abilities are one of the major transdiagnostic domains in the National Institute of Mental Health’s Research Domain Criteria (RDoC). Following RDoC’s integrative approach, we aimed to develop brain-based predictive models for cog…
View article: Sub-diagnostic effects of genetic variants associated with autism
Sub-diagnostic effects of genetic variants associated with autism Open
While over a hundred genes are significantly associated with autism, little is known about the prevalence of variants affecting them in the general population. Nor do we fully appreciate the phenotypic diversity beyond the formal autism di…
View article: A Genetics-First Approach to Dissecting the Heterogeneity of Autism: Phenotypic Comparison of Autism Risk Copy Number Variants
A Genetics-First Approach to Dissecting the Heterogeneity of Autism: Phenotypic Comparison of Autism Risk Copy Number Variants Open
Many CNV carriers do not meet full diagnostic criteria for autism but nevertheless meet clinical cutoffs for autistic traits. Although profile differences between variants were observed, there is considerable variability in clinical sympto…
View article: Effects of Thyroid Status on Regional Brain Volumes: A Diagnostic and Genetic Imaging Study in UK Biobank
Effects of Thyroid Status on Regional Brain Volumes: A Diagnostic and Genetic Imaging Study in UK Biobank Open
Background Thyroid hormone is essential for optimal human neurodevelopment and may modify the risk of attention-deficit/hyperactivity disorder (ADHD). However, the brain structures involved are unknown and it is unclear if the adult brain …
View article: Identifying genetic variants associated with cerebellar volume in 33,265 individuals from the UK-Biobank
Identifying genetic variants associated with cerebellar volume in 33,265 individuals from the UK-Biobank Open
There is expanding interest in researching the cerebellum given accumulating evidence of its important contributions to cognitive and emotional functions, in addition to more established sensorimotor roles. While large genome-wide associat…
View article: Functional impact of global rare copy number variation in autism spectrum disorders
Functional impact of global rare copy number variation in autism spectrum disorders Open
The autism spectrum disorders (ASDs) are a group of conditions characterized by impairments in reciprocal social interaction and communication, and the presence of restricted and repetitive behaviors1. Individuals with an ASD vary greatly …