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View article: Exercise rehabilitation for people with postural tachycardia syndrome at two secondary care centres in the UK: the PULSE feasibility randomised controlled trial
Exercise rehabilitation for people with postural tachycardia syndrome at two secondary care centres in the UK: the PULSE feasibility randomised controlled trial Open
Objectives The aim of the study was to assess the feasibility of conducting a definitive multicentre randomised controlled trial (RCT) testing an online exercise rehabilitation and behavioural/motivational support intervention for people w…
View article: Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology
Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology Open
Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method for evaluating functional capacity, with oxygen pulse (O 2 Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agre…
View article: Rising arterial stiffness with accumulating comorbidities associates with heart failure with preserved ejection fraction
Rising arterial stiffness with accumulating comorbidities associates with heart failure with preserved ejection fraction Open
Aims Comorbidities play a significant role towards the pathophysiology of heart failure with preserved ejection fraction (HFpEF), characterized by abnormal macrovascular function and altered ventricular–vascular coupling. However, our unde…
View article: Paediatric MRI scans: a regional service evaluation
Paediatric MRI scans: a regional service evaluation Open
Background: In paediatric patients, general anaesthesia (GA) is often required to obtain complete magnetic resonance imaging (MRI) scans without motion artifact,1 with associated risks and costs.2 3 We performed a retrospective review of s…
View article: Co-creation of a complex, multicomponent rehabilitation intervention and feasibility trial protocol for the PostUraL tachycardia Syndrome Exercise (PULSE) study
Co-creation of a complex, multicomponent rehabilitation intervention and feasibility trial protocol for the PostUraL tachycardia Syndrome Exercise (PULSE) study Open
Background: There is a dearth of research to support the treatment of people with Postural Tachycardia Syndrome (PoTS). Despite expert consensus suggesting exercise is recommended for this patient group, there are no randomised control tri…
View article: High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial
High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial Open
Background There is a lack of international consensus regarding the prescription of high-intensity interval training (HIIT) for people with coronary artery disease (CAD) attending cardiac rehabilitation (CR). Aims To assess the clinical ef…
View article: Remote maintenance cardiac rehabilitation (MAINTAIN): A protocol for a randomised feasibility study
Remote maintenance cardiac rehabilitation (MAINTAIN): A protocol for a randomised feasibility study Open
Background Long-term adherence to exercise is often poor for people with coronary heart disease (CHD) who have completed supervised, centre-based cardiac rehabilitation. The aim of this study is to assess the feasibility of a remotely pres…
View article: 7 Remote maintenance cardiac rehabilitation (MAINTAIN): a protocol for a randomised feasibility study
7 Remote maintenance cardiac rehabilitation (MAINTAIN): a protocol for a randomised feasibility study Open
Background Long-term adherence to exercise is often poor for people with coronary heart disease (CHD) who have completed supervised, centre-based cardiac rehabilitation. Wearable activity devices with personalised feedback may remotely sup…
View article: Effectiveness and Safety of Early Initiation of Poststernotomy Cardiac Rehabilitation Exercise Training
Effectiveness and Safety of Early Initiation of Poststernotomy Cardiac Rehabilitation Exercise Training Open
ClinicalTrials.gov Identifier: NCT03223558.
View article: Protocol update for a randomised controlled feasibility trial of exercise rehabilitation for people with postural tachycardia syndrome: the PULSE study
Protocol update for a randomised controlled feasibility trial of exercise rehabilitation for people with postural tachycardia syndrome: the PULSE study Open
Background The PULSE (PostUraL tachycardia Syndrome Exercise) study is a randomised controlled trial assessing the feasibility of conducting a multicentre RCT testing supervised exercise rehabilitation with behavioural and motivational sup…
View article: Use of Lipid-Lowering Therapies Over 2 Years in GOULD, a Registry of Patients With Atherosclerotic Cardiovascular Disease in the US
Use of Lipid-Lowering Therapies Over 2 Years in GOULD, a Registry of Patients With Atherosclerotic Cardiovascular Disease in the US Open
Of patients with ASCVD, most with suboptimal LDL-C levels at baseline, only 17.1% had LLT intensification after 2 years, and two-thirds remained at an LDL-C level greater than 70 mg/dL. Further intensive efforts are needed to achieve optim…
View article: Vietnam
Vietnam Open
The author served as an Army optometrist in Vietnam for one year in 1969-70. He discusses his experiences providing optometric care in a combat zone and comments on how those experiences influenced his subsequent career in private practice.
View article: Does contemporary exercise-based cardiac rehabilitation improve quality of life for people with coronary artery disease? A systematic review and meta-analysis
Does contemporary exercise-based cardiac rehabilitation improve quality of life for people with coronary artery disease? A systematic review and meta-analysis Open
Objectives To determine the effect of contemporary exercise-based cardiac rehabilitation on generic and disease-specific health related quality of life for people with coronary artery disease. Design Systematic review and meta-analysis. St…
View article: Heart failure with preserved ejection fraction (HFpEF) pathophysiology study (IDENTIFY-HF): does increased arterial stiffness associate with HFpEF, in addition to ageing and vascular effects of comorbidities? Rationale and design
Heart failure with preserved ejection fraction (HFpEF) pathophysiology study (IDENTIFY-HF): does increased arterial stiffness associate with HFpEF, in addition to ageing and vascular effects of comorbidities? Rationale and design Open
Aims There has been a paradigm shift proposing that comorbidities are a major contributor towards the heart failure with preserved ejection fraction (HFpEF) syndrome. Furthermore, HFpEF patients have abnormal macrovascular and microvascula…
View article: Exercise rehabilitation programmes for pulmonary hypertension: a systematic review of intervention components and reporting quality
Exercise rehabilitation programmes for pulmonary hypertension: a systematic review of intervention components and reporting quality Open
Objectives To identify the components, and assess the reporting quality, of exercise training interventions for people living with pulmonary hypertension. Design Systematic review with analysis of intervention reporting quality using the C…
View article: Feasibility and effects of intra-dialytic low-frequency electrical muscle stimulation and cycle training: A pilot randomized controlled trial
Feasibility and effects of intra-dialytic low-frequency electrical muscle stimulation and cycle training: A pilot randomized controlled trial Open
Ten weeks of intra-dialytic LF-EMS or cycling improved cardio-respiratory reserve and muscular strength. For patients who are unable or unwilling to cycle during dialysis, LF-EMS is a feasible alternative.
View article: Is exercise-based cardiac rehabilitation effective? A systematic review and meta-analysis to re-examine the evidence
Is exercise-based cardiac rehabilitation effective? A systematic review and meta-analysis to re-examine the evidence Open
Objectives To determine the contemporary effectiveness of exercise-based cardiac rehabilitation (CR) in terms of all-cause mortality, cardiovascular mortality and hospital admissions. Data sources Studies included in or meeting the entry c…
View article: Early initiation of post-sternotomy cardiac rehabilitation exercise training (SCAR): study protocol for a randomised controlled trial and economic evaluation
Early initiation of post-sternotomy cardiac rehabilitation exercise training (SCAR): study protocol for a randomised controlled trial and economic evaluation Open
Introduction Current guidelines recommend abstinence from supervised cardiac rehabilitation (CR) exercise training for 6 weeks post-sternotomy. This practice is not based on empirical evidence, thus imposing potentially unnecessary activit…
View article: Statistical Design of Experiments to Ensure “Rigor and Reproducibility” in Imaging Sciences
Statistical Design of Experiments to Ensure “Rigor and Reproducibility” in Imaging Sciences Open
Journal Article Statistical Design of Experiments to Ensure “Rigor and Reproducibility” in Imaging Sciences Get access Vishwas N Joshi, Vishwas N Joshi Nanoprobes, Incorporated, 95 Horseblock Road, Unit 1, Yaphank, NY, USA Search for other…
View article: Gold Nanoparticle Photoaffinity Labels for Electron Microscopy
Gold Nanoparticle Photoaffinity Labels for Electron Microscopy Open
Journal Article Gold Nanoparticle Photoaffinity Labels for Electron Microscopy Get access Vishwas N Joshi, Vishwas N Joshi Nanoprobes, Incorporated; 95 Horseblock Road, Unit 1; Yaphank, NY Search for other works by this author on: Oxford A…
View article: Gold Nanoparticle Technology to Address Variability in EM Labeling
Gold Nanoparticle Technology to Address Variability in EM Labeling Open
Journal Article Gold Nanoparticle Technology to Address Variability in EM Labeling Get access Richard D Powell, Richard D Powell Nanoprobes, Incorporated, 95 Horseblock Road, Unit 1, Yaphank, NY, USA Search for other works by this author o…
View article: High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation
High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation Open
Introduction Current international guidelines for cardiac rehabilitation (CR) advocate moderate-intensity exercise training (MISS, moderate-intensity steady state). This recommendation predates significant advances in medical therapy for c…