Richard Komakech
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View article: SMART-HERBALOMICS: An innovative multi-omics approach to studying medicinal plants grown in controlled systems such as phytotrons
SMART-HERBALOMICS: An innovative multi-omics approach to studying medicinal plants grown in controlled systems such as phytotrons Open
This article introduces SH for the first time as an integrative approach that offers a comprehensive and sustainable pathway to develop standardized, safe, and evidence-based herbal therapies. It bridges the fields of ethnopharmacology and…
View article: Agricultural sustainability through smart farming systems: A comparative analysis between the Republic of Korea and Republic of Uganda
Agricultural sustainability through smart farming systems: A comparative analysis between the Republic of Korea and Republic of Uganda Open
Kenneth Happy ・ Roggers Gang ・ Yeongjun Ban ・ Sungyu Yang ・ Endang Rahmat ・ Denis Okello ・ Richard Komakech ・ Okello Cyrus ・ Kalule Okello David ・ Youngmin Kang. J Plant Biotechnol 2024;51:167-201. https://doi.org/10.5010/JPB.2024.51.018.1…
View article: Comparative antiplasmodial activity, cytotoxicity, and phytochemical contents of <i>Warburgia ugandensis</i> stem bark against <i>Aspilia africana</i> wild and <i>in vitro</i> regenerated tissues
Comparative antiplasmodial activity, cytotoxicity, and phytochemical contents of <i>Warburgia ugandensis</i> stem bark against <i>Aspilia africana</i> wild and <i>in vitro</i> regenerated tissues Open
Denis Okello ･Jeremiah Gathirwa ･Alice Wanyoko ･Richard Komakech ･Yuseong Chung ･Roggers Gang ･ Francis Omujal ･Youngmin Kang. J Plant Biotechnol 2023;50:97-107. https://doi.org/10.5010/JPB.2023.50.013.097
View article: Assessment of anatomical characteristics of the medicinal plant African cherry (<i>Prunus africana</i>) for its accurate taxonomic identification
Assessment of anatomical characteristics of the medicinal plant African cherry (<i>Prunus africana</i>) for its accurate taxonomic identification Open
Richard Komakech ·Sungyu Yang ·Jun Ho Song ·Goya Choi ·Yong-Goo Kim·Denis Okello · Francis Omujal ·Grace Nambatya Kyeyune ·Motlalepula Gilbert Matsabisa ·Youngmin Kang. J Plant Biotechnol 2022;49:139-44. https://doi.org/10.5010/JPB.2022.49…
View article: GC–MS and LC-TOF–MS profiles, toxicity, and macrophage-dependent in vitro anti-osteoporosis activity of Prunus africana (Hook f.) Kalkman Bark
GC–MS and LC-TOF–MS profiles, toxicity, and macrophage-dependent in vitro anti-osteoporosis activity of Prunus africana (Hook f.) Kalkman Bark Open
Osteoporosis affects millions of people worldwide. As such, this study assessed the macrophage-dependent in vitro anti-osteoporosis, phytochemical profile and hepatotoxicity effects in zebrafish larvae of the stem bark extracts of P. afric…
View article: Root Extract of a Micropropagated Prunus africana Medicinal Plant Induced Apoptosis in Human Prostate Cancer Cells (PC-3) via Caspase-3 Activation
Root Extract of a Micropropagated Prunus africana Medicinal Plant Induced Apoptosis in Human Prostate Cancer Cells (PC-3) via Caspase-3 Activation Open
Prostate cancer is one of the major causes of cancer-related deaths among men globally. Medicinal plants have been explored as alternative treatment options. Herein, we assessed the in vitro cytotoxic effects of 70% ethanolic root extracts…
View article: Indirect in vitro Regeneration of the Medicinal Plant, Aspilia africana, and Histological Assessment at Different Developmental Stages
Indirect in vitro Regeneration of the Medicinal Plant, Aspilia africana, and Histological Assessment at Different Developmental Stages Open
The medicinal plant, Aspilia africana , has been traditionally used in several African countries to treat many diseases such as tuberculosis, cough, inflammation, malaria, osteoporosis, and diabetes. In this study, we developed a protocol …
View article: Scale-up production of Rehmannia glutinosa adventitious root biomass in bioreactors and improvement of its acteoside content by elicitation
Scale-up production of Rehmannia glutinosa adventitious root biomass in bioreactors and improvement of its acteoside content by elicitation Open
Rehmannia glutinosa is an important medicinal crop that has been widely used globally to treat various ailments such as hematinic deficiencies, diabetes, and adrenal disorders. To provide a sustainable supply to meet large demands, alterna…
View article: Antioxidant Activity, Polyphenolic Content, and FT-NIR Analysis of Different Aspilia africana Medicinal Plant Tissues
Antioxidant Activity, Polyphenolic Content, and FT-NIR Analysis of Different Aspilia africana Medicinal Plant Tissues Open
Aspilia africana has been used for generations to treat many diseases in Africa. Its biological activities, including antioxidant and anti-inflammatory potential, are attributed to a number of secondary metabolites, including alkaloids and…
View article: Anatomical Characteristics of African Cherry (Prunus Africana) Medicinal Plant for its Accurate Taxonomic Identification
Anatomical Characteristics of African Cherry (Prunus Africana) Medicinal Plant for its Accurate Taxonomic Identification Open
Background: The genus Prunus (Family Rosaceae) comprises over 400 plant species and exhibits vast biodiversity worldwide. Due to its wide distribution, its taxonomic classification is important. Anatomical characters are conserved and stab…
View article: An in vitro Propagation of Aspilia africana (Pers.) C. D. Adams, and Evaluation of Its Anatomy and Physiology of Acclimatized Plants
An in vitro Propagation of Aspilia africana (Pers.) C. D. Adams, and Evaluation of Its Anatomy and Physiology of Acclimatized Plants Open
Aspilia africana (Pers.) C. D. Adams is an important medicinal plant, that has been used as traditional medicine in many African countries for the treatment of various health problems, including inflammatory conditions, osteoporosis, tuber…
View article: Effects of commercial soils on germination, early growth, and chlorophyll content of <i>Aspilia africana</i>, a medicinal plant
Effects of commercial soils on germination, early growth, and chlorophyll content of <i>Aspilia africana</i>, a medicinal plant Open
Other SectionsAbstractIntroductionMaterials and MethodResultsDiscussionConclusionAcknowledgementsConflict of interestReference
View article: A Micropropagation Protocol for the Endangered Medicinal Tree Prunus africana (Hook f.) Kalkman: Genetic Fidelity and Physiological Parameter Assessment
A Micropropagation Protocol for the Endangered Medicinal Tree Prunus africana (Hook f.) Kalkman: Genetic Fidelity and Physiological Parameter Assessment Open
Prunus africana is an endangered medicinal plant and hence new propagation methods are urgently required to increase its populations. Unfortunately, propagation through seeds is challenging due to its long flowering cycle and recalcitrant …
View article: Verification of the Field Productivity and Bioequivalence of a Medicinal Plant (Polygonum multiflorum) Developed Using an In Vitro Culture Method
Verification of the Field Productivity and Bioequivalence of a Medicinal Plant (Polygonum multiflorum) Developed Using an In Vitro Culture Method Open
Polygonum multiflorum Thunb. is a perennial plant that belongs to Polygonaceae. Root tissues are the main plant parts used as medicinal herbs in Korean oriental medicine. The P. multiflorum tuber is well known for its medicinal properties …
View article: Verification of the Field Productivity of Rehmannia glutinosa (Gaertn.) DC. Developed Through Optimized In Vitro Culture Method
Verification of the Field Productivity of Rehmannia glutinosa (Gaertn.) DC. Developed Through Optimized In Vitro Culture Method Open
Rehmannia glutinosa (Gaertn.) DC is a perennial plant belonging to the family Scropulariidae. The root of R. glutinosa is used in oriental medicine and mainly grown using rootstock rather than seed cultivation, which gives rise to several …
View article: Effects of Processed <i>Polygonum multiflorum</i> with KIOM Patent on Bone Remodeling‐Related Protein Expression in Human Osteoblast‐Like SaOS‐2 Cells
Effects of Processed <i>Polygonum multiflorum</i> with KIOM Patent on Bone Remodeling‐Related Protein Expression in Human Osteoblast‐Like SaOS‐2 Cells Open
This present study evaluated the effects of processed P. multiflorum on osteogenesis using Sarcoma osteogenic (SaOS‐2) cell lines and osteoclastogenesis of bone marrow‐derived macrophage cells (BMM) and to elucidate differences in effect o…
View article: <i>In Vitro</i> Antiosteoporosis Activity and Hepatotoxicity Evaluation in Zebrafish Larvae of Bark Extracts of <i>Prunus jamasakura</i> Medicinal Plant
<i>In Vitro</i> Antiosteoporosis Activity and Hepatotoxicity Evaluation in Zebrafish Larvae of Bark Extracts of <i>Prunus jamasakura</i> Medicinal Plant Open
Osteoporosis is one of the main health problems in the world today characterized by low bone mass and deterioration in bone microarchitecture. In recent years, the use of natural products approach to treat it has been in the increase. In t…
View article: Anti-inflammatory and analgesic potential of Tamarindus indica Linn. (Fabaceae): a narrative review
Anti-inflammatory and analgesic potential of Tamarindus indica Linn. (Fabaceae): a narrative review Open
Chronic inflammation is one of the causes of a number of non-infectious diseases in the world. Over the years, Tamarindus indica has played fundamental roles in traditional medicine as an anti-inflammatory and analgesic drug. It is a comme…
View article: The Wound Healing Potential of<i> Aspilia africana</i> (Pers.) C. D. Adams (Asteraceae)
The Wound Healing Potential of<i> Aspilia africana</i> (Pers.) C. D. Adams (Asteraceae) Open
Wounds remain one of the major causes of death worldwide. Over the years medicinal plants and natural compounds have played an integral role in wound treatment. Aspilia africana (Pers.) C. D. Adams which is classified among substances with…
View article: Maximizing seedling and root tuber production in Polygonum multiflorum for use in ethnomedicine
Maximizing seedling and root tuber production in Polygonum multiflorum for use in ethnomedicine Open
There is need for a robust production mechanisms to meet the ever increasing demand for herbal medicine in the world today. In this study, we developed a standard protocol for the in vitro culture of Polygonum multiflorum to rapidly produc…
View article: Traditional Indian medicine (TIM) and traditional Korean medicine (TKM): aconstitutional-based concept and comparison
Traditional Indian medicine (TIM) and traditional Korean medicine (TKM): aconstitutional-based concept and comparison Open
Traditional and complementary medicine (T&CM) plays an integral role in providing health care worldwide. It is based on sound fundamental principles and centuries of practices. This study compared traditional Indian medicine (TIM) and trad…
View article: A Review of the Potential of Phytochemicals from <i>Prunus africana</i> (Hook f.) Kalkman Stem Bark for Chemoprevention and Chemotherapy of Prostate Cancer
A Review of the Potential of Phytochemicals from <i>Prunus africana</i> (Hook f.) Kalkman Stem Bark for Chemoprevention and Chemotherapy of Prostate Cancer Open
Prostate cancer remains one of the major causes of death worldwide. In view of the limited treatment options for patients with prostate cancer, preventive and treatment approaches based on natural compounds can play an integral role in tac…