Richard M. Ruddy
YOU?
Author Swipe
View article: Derivation and validation of the Pediatric Community‐Acquired Pneumonia Severity (PedCAPS) score: A prospective cohort study
Derivation and validation of the Pediatric Community‐Acquired Pneumonia Severity (PedCAPS) score: A prospective cohort study Open
Introduction Community‐acquired pneumonia (CAP) is a frequent and costly cause of pediatric emergency department (ED) visits and hospitalizations. Previous prognostic tools for CAP are limited by small samples, single‐center or retrospecti…
View article: E060 Casting post intra-articular steroid injection to treat fixed flexion deformity in patients with juvenile idiopathic arthritis
E060 Casting post intra-articular steroid injection to treat fixed flexion deformity in patients with juvenile idiopathic arthritis Open
Background/Aims Children with Juvenile Idiopathic Arthritis (JIA) who present to the National Centre for Paediatric Rheumatology (NCPR) with active inflammation of a knee or elbow joint in conjunction with a fixed flexion deformity (FFD) o…
View article: Epidemiology of diagnostic errors in pediatric emergency departments using electronic triggers
Epidemiology of diagnostic errors in pediatric emergency departments using electronic triggers Open
Objectives We applied three electronic triggers to study frequency and contributory factors of missed opportunities for improving diagnosis (MOIDs) in pediatric emergency departments (EDs): return visits within 10 days resulting in admissi…
View article: Time to Clinical Stability in Children With Community-Acquired Pneumonia
Time to Clinical Stability in Children With Community-Acquired Pneumonia Open
BACKGROUND AND OBJECTIVES Time to clinical stability (TCS) is a commonly used outcome in adults with community-acquired pneumonia (CAP), yet few studies have evaluated TCS in children. Our objective was to determine the association between…
View article: Assessing the Revised Safer Dx Instrument <sup>®</sup> in the understanding of ambulatory system design changes for type 1 diabetes and autism spectrum disorder in pediatrics
Assessing the Revised Safer Dx Instrument <sup>®</sup> in the understanding of ambulatory system design changes for type 1 diabetes and autism spectrum disorder in pediatrics Open
Objectives We sought within an ambulatory safety study to understand if the Revised Safer Dx instrument may be helpful in identification of diagnostic missed opportunities in care of children with type 1 diabetes (T1D) and autism spectrum …
View article: Viral Detection Is Associated With Severe Disease in Children With Suspected Community-Acquired Pneumonia
Viral Detection Is Associated With Severe Disease in Children With Suspected Community-Acquired Pneumonia Open
Objective To evaluate the role of virus detection on disease severity among children presenting to the emergency department (ED) with suspected community-acquired pneumonia (CAP). Methods We performed a single-center prospective study of c…
View article: Impact of Adjunct Corticosteroid Therapy on Quality of Life for Children With Suspected Pneumonia
Impact of Adjunct Corticosteroid Therapy on Quality of Life for Children With Suspected Pneumonia Open
Objective To determine the association between adjunct corticosteroid therapy and quality of life (QoL) outcomes in children with signs and symptoms of lower respiratory tract infection and clinical suspicion for community-acquired pneumon…
View article: Safer Type 1 Diabetes Care at Home: SEIPS-based Process Mapping with Parents and Clinicians
Safer Type 1 Diabetes Care at Home: SEIPS-based Process Mapping with Parents and Clinicians Open
Introduction: The limited data indicate that pediatric medical errors in the outpatient setting, including at home, are common. This study is the first step of our Ambulatory Pediatric Patient Safety Learning Lab to address medication erro…
View article: Types of diagnostic errors reported by paediatric emergency providers in a global paediatric emergency care research network
Types of diagnostic errors reported by paediatric emergency providers in a global paediatric emergency care research network Open
Background Diagnostic errors, reframed as missed opportunities for improving diagnosis (MOIDs), are poorly understood in the paediatric emergency department (ED) setting. We investigated the clinical experience, harm and contributing facto…
View article: Developing Consensus on Clinical Outcomes for Children with Mild Pneumonia: A Delphi Study
Developing Consensus on Clinical Outcomes for Children with Mild Pneumonia: A Delphi Study Open
Background The absence of consensus for outcomes in pediatric antibiotic trials is a major barrier to research harmonization and clinical translation. We sought to develop expert consensus on study outcomes for clinical trials of children …
View article: Antibiotic use and outcomes among children hospitalized with suspected pneumonia
Antibiotic use and outcomes among children hospitalized with suspected pneumonia Open
Background Although viral etiologies predominate, antibiotics are frequently prescribed for community‐acquired pneumonia (CAP). Objective We evaluated the association between antibiotic use and outcomes among children hospitalized with sus…
View article: Incorporation of biomarkers into a prediction model for paediatric radiographic pneumonia
Incorporation of biomarkers into a prediction model for paediatric radiographic pneumonia Open
Objective The aim of this study was to evaluate biomarkers to predict radiographic pneumonia among children with suspected lower respiratory tract infections (LRTI). Methods We performed a single-centre prospective cohort study of children…
View article: Feasibility and reliability of telemedicine examinations for respiratory distress in children: A pilot study
Feasibility and reliability of telemedicine examinations for respiratory distress in children: A pilot study Open
Respiratory disorders are a leading cause of acute care visits by children. Data establishing the reliability of telemedicine in evaluating children with respiratory concerns are limited. The overall objective of this pilot study was to ev…
View article: Serious Bacterial Infections in Young Febrile Infants With Positive Urinalysis Results
Serious Bacterial Infections in Young Febrile Infants With Positive Urinalysis Results Open
It is unknown whether febrile infants 29 to 60 days old with positive urinalysis results require routine lumbar punctures for evaluation of bacterial meningitis. OBJECTIVE To determine the prevalence of bacteremia and/or bacterial meningit…
View article: Factors Associated With Antibiotic Use for Children Hospitalized With Pneumonia
Factors Associated With Antibiotic Use for Children Hospitalized With Pneumonia Open
BACKGROUND Antibiotics are frequently used for community-acquired pneumonia (CAP), although viral etiologies predominate. We sought to determine factors associated with antibiotic use among children hospitalized with suspected CAP. METHODS…
View article: Validation of Prediction Models for Pneumonia Among Children in the Emergency Department
Validation of Prediction Models for Pneumonia Among Children in the Emergency Department Open
BACKGROUND Several prediction models have been reported to identify patients with radiographic pneumonia, but none have been validated or broadly implemented into practice. We evaluated 5 prediction models for radiographic pneumonia in chi…
View article: A Prediction Model for Pediatric Radiographic Pneumonia
A Prediction Model for Pediatric Radiographic Pneumonia Open
BACKGROUND Chest radiographs (CXRs) are frequently used in the diagnosis of community-acquired pneumonia (CAP). We sought to construct a predictive model for radiographic CAP based on clinical features to decrease CXR use. METHODS We perfo…
View article: 999. Nasal Mucosal Cytokines: Potential Biomarkers for Pediatric Pneumonia Severity and Etiology
999. Nasal Mucosal Cytokines: Potential Biomarkers for Pediatric Pneumonia Severity and Etiology Open
Background Community acquired pneumonia (CAP) is a leading cause of mortality in children < 5 years, but our understanding of disease pathogenesis remains limited. The objective of this study was to define the local host immune response…
View article: Respiratory Colonization and Short-Term Temporal Changes in the Urinary Metabolome of Children
Respiratory Colonization and Short-Term Temporal Changes in the Urinary Metabolome of Children Open
The human metabolome may vary based on age, over time, and in the presence of viral carriage and bacterial colonization—a common scenario in children. We used nuclear magnetic resonance spectroscopy to identify and quantify urinary metabol…
View article: Predictive Value of Clinician “Gestalt” in Pediatric Community-Acquired Pneumonia
Predictive Value of Clinician “Gestalt” in Pediatric Community-Acquired Pneumonia Open
OBJECTIVES: Validated prognostic tools for pediatric community-acquired pneumonia (CAP) do not exist. Thus, clinicians rely on “gestalt” in management decisions for children with CAP. We sought to determine the ability of clinician gestalt…
View article: Development and Internal Validation of a Prediction Model to Risk Stratify Children With Suspected Community-Acquired Pneumonia
Development and Internal Validation of a Prediction Model to Risk Stratify Children With Suspected Community-Acquired Pneumonia Open
Background Although community-acquired pneumonia (CAP) is one of the most common infections in children, no tools exist to risk stratify children with suspected CAP. We developed and validated a prediction model to risk stratify and inform…
View article: Proadrenomedullin Predicts Severe Disease in Children With Suspected Community-acquired Pneumonia
Proadrenomedullin Predicts Severe Disease in Children With Suspected Community-acquired Pneumonia Open
Background Proadrenomedullin (proADM), a vasodilatory peptide with antimicrobial and anti-inflammatory properties, predicts severe outcomes in adults with community-acquired pneumonia (CAP) to a greater degree than C-reactive protein and p…
View article: Biomarkers and Disease Severity in Children With Community-Acquired Pneumonia
Biomarkers and Disease Severity in Children With Community-Acquired Pneumonia Open
BACKGROUND: Host biomarkers predict disease severity in adults with community-acquired pneumonia (CAP). We evaluated the association of the white blood cell (WBC) count, absolute neutrophil count (ANC), C-reactive protein (CRP), and procal…
View article: Antibiotic Use and Outcomes in Children in the Emergency Department With Suspected Pneumonia
Antibiotic Use and Outcomes in Children in the Emergency Department With Suspected Pneumonia Open
BACKGROUND AND OBJECTIVES: Antibiotic therapy is often prescribed for suspected community-acquired pneumonia (CAP) in children despite a lack of knowledge of causative pathogen. Our objective in this study was to investigate the associatio…
View article: Validation of the British Thoracic Society Severity Criteria for Pediatric Community-acquired Pneumonia
Validation of the British Thoracic Society Severity Criteria for Pediatric Community-acquired Pneumonia Open
Background: The British Thoracic Society (BTS) guideline for pediatric community-acquired pneumonia (CAP) outlines severity criteria to guide clinical decision-making. Our objective was to examine the predictive performance of the criteria…
View article: Diagnostic Testing and Antibiotic Use in Young Children With Community-Acquired Pneumonia in the United States, 2008–2015
Diagnostic Testing and Antibiotic Use in Young Children With Community-Acquired Pneumonia in the United States, 2008–2015 Open
Diagnostic testing and antibiotics are not routinely recommended for young children with community-acquired pneumonia. In a national sample of >6 million outpatient 1- to 6-year-olds with community-acquired pneumonia between 2008 and 20…
View article: A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections
A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections Open
We derived and validated an accurate prediction rule to identify febrile infants 60 days and younger at low risk for SBIs using the urinalysis, ANC, and procalcitonin levels. Once further validated on an independent cohort, clinical applic…
View article: 261. Alternative Antibiotic Prescribing for Community Acquired Pneumonia (CAP) in Pediatric Patients in Relation to Allergy Status
261. Alternative Antibiotic Prescribing for Community Acquired Pneumonia (CAP) in Pediatric Patients in Relation to Allergy Status Open
BACKGROUND: While 10% of the population may report a penicillin (PCN) allergy, it has been shown that 90% of these patients are not allergic and may still be able to take PCN safely. Inaccurate reporting of a PCN allergy may lead to prescr…