Richard Schulz
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View article: Matrix metalloproteinase inhibition protects against junctophilin‐2 proteolysis during doxorubicin‐induced cardiotoxicity
Matrix metalloproteinase inhibition protects against junctophilin‐2 proteolysis during doxorubicin‐induced cardiotoxicity Open
Background and Purpose Treatment of cancer patients with anthracyclines is known to cause dose‐dependent cardiotoxicity through several mechanisms including enhanced oxidative stress, ultimately resulting in defective excitation–contractio…
View article: MMP-2 inhibition attenuates ER stress-mediated cell death during myocardial ischemia-reperfusion injury by preserving IRE1α
MMP-2 inhibition attenuates ER stress-mediated cell death during myocardial ischemia-reperfusion injury by preserving IRE1α Open
Endoplasmic reticulum (ER) stress is one of the major events accompanying myocardial ischemia-reperfusion (IR) injury, as hypoxia and oxidative stress disrupt protein folding in the ER. As a result, the unfolded protein response (UPR) is a…
View article: EFFECTS OF CHILDCARE, WORK, AND CAREGIVING INTENSITY ON MALE AND FEMALE FAMILY CAREGIVERS
EFFECTS OF CHILDCARE, WORK, AND CAREGIVING INTENSITY ON MALE AND FEMALE FAMILY CAREGIVERS Open
Objectives The Behavioral Risk Factor Surveillance System sampled 54,076 caregivers between 2015 and 2017 providing an opportunity to evaluate risk factors for poor mental and physical health among a representative sample of U.S. adult car…
View article: Novel methods for assessment of vulnerability to financial exploitation (FE)
Novel methods for assessment of vulnerability to financial exploitation (FE) Open
Financial exploitation (FE) is a complex problem influenced by many factors. This article introduces two novel methods for assessment of FE vulnerability: (1) performance-based measures of financial skills using web-based simulations of co…
View article: Effects of Childcare, Work, and Caregiving Intensity on Male and Female Family Caregivers
Effects of Childcare, Work, and Caregiving Intensity on Male and Female Family Caregivers Open
Objectives The Behavioral Risk Factor Surveillance System sampled 54,076 caregivers between 2015 and 2017 providing an opportunity to evaluate risk factors for poor mental and physical health among a representative sample of U.S. adult car…
View article: Evaluation of Face Validity and Acceptability of the Care Partner Hospital Assessment Tool
Evaluation of Face Validity and Acceptability of the Care Partner Hospital Assessment Tool Open
Background and Objectives Care partners of hospitalized older adults report their caregiving needs are not being addressed. The Care Partner Hospital Assessment Tool (CHAT) is a feasible and appropriate tool for practitioners’ use with car…
View article: The Role of Preparedness for Caregiving on the Relationship Between Caregiver Distress and Potentially Harmful Behaviors
The Role of Preparedness for Caregiving on the Relationship Between Caregiver Distress and Potentially Harmful Behaviors Open
This work extends research suggesting a link between indicators of distress among informal caregivers (CG) (e.g., depression and burden), and potentially harmful behaviors (PHB), including feeling like yelling or screaming at the care reci…
View article: FINANCIAL SCAMS TARGETING OLDER ADULTS DURING COVID-19
FINANCIAL SCAMS TARGETING OLDER ADULTS DURING COVID-19 Open
The COVID pandemic afforded financial scammers with new opportunities to target older adults. This paper presents data from a telephone survey conducted June–September, 2020 with 380 participants from a larger National Institute of Aging s…
View article: Evaluating the Appropriateness and Feasibility of the Care Partner Hospital Assessment Tool (CHAT)
Evaluating the Appropriateness and Feasibility of the Care Partner Hospital Assessment Tool (CHAT) Open
Hospital practitioners rely on care partners of older adults to provide complex care without identifying and addressing their needs. The Care Partner Hospital Assessment Tool (CHAT) was developed to identify the education skill training ne…
View article: Examining Mental and Physical Health Status Among Sandwich Generation Caregivers
Examining Mental and Physical Health Status Among Sandwich Generation Caregivers Open
With a sample of 54,076 caregivers, the Behavioral Risk Factor Surveillance System (BRFSS, 2015-2017) provides an opportunity to assess the impact of caregiving on U.S. adults varying in age, gender, and race. We focused on sandwich genera…
View article: Caregiving Self-efficacy as a Mediator of Negative Emotional States and Potentially Harmful Behaviors
Caregiving Self-efficacy as a Mediator of Negative Emotional States and Potentially Harmful Behaviors Open
Potentially harmful behaviors (PHB), such as wanting to scream at or hit a care recipient, are more likely when caregivers experience higher levels of stress. The current study expands on this research and identifies caregiving self-effica…
View article: Family Caregiving for Persons With Emotional, Developmental, and Behavioral Disorders During COVID-19
Family Caregiving for Persons With Emotional, Developmental, and Behavioral Disorders During COVID-19 Open
COVID-19 has the potential to exacerbate stresses of family caregiving. While studies during COVID-19 have focused on caregivers of those with memory / cognitive issues like Alzheimer’s Disease, less attention has been paid to those caring…
View article: Bridging the Family Care Gap
Bridging the Family Care Gap Open
This symposium aims to create a scientific and policy roadmap to offset the impending shortage of family caregivers available to assist older adults in the U.S. (i.e., the “family care gap”). Drawing on public health, cultural frameworks, …
View article: Compassion in dementia caregiving: Psychometric properties of the Caregiving Compassion Scale in Spanish caregivers
Compassion in dementia caregiving: Psychometric properties of the Caregiving Compassion Scale in Spanish caregivers Open
Compassion has been suggested as a relevant variable for understanding dementia caregivers’ psychological distress. The objectives were to analyse the psychometric properties of the Caregiving Compassion Scale (CCS) and to explore the asso…
View article: Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study
Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study Open
The purpose of this pilot study was to assess Chronic Myeloid Leukemia (CML) patients’ adherence to, beliefs about, and barriers to oral anticancer agents (OAC) using brief self-report measures in community-based cancer clinics. Patients c…
View article: The Development and Content Validation of the Care Partner Hospital Assessment Tool
The Development and Content Validation of the Care Partner Hospital Assessment Tool Open
Background/Objectives: When aging adults are hospitalized due to a major health event, they often turn to care partners (‘family members or friends’) for support. Assessment of care partners’ needs during hospital care may be important to …
View article: Family Caregiving During the COVID-19 Pandemic
Family Caregiving During the COVID-19 Pandemic Open
Background and Objectives The coronavirus disease 2019 (COVID-19) pandemic has negatively affected persons with existing chronic health conditions. The pandemic also has the potential to exacerbate the stresses of family caregiving. We com…
View article: Are family caregivers willing to pay for support interventions?
Are family caregivers willing to pay for support interventions? Open
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View article: Vulnerability to Financial Scams Among Older Adults: Cognitive and Psychosocial Factors
Vulnerability to Financial Scams Among Older Adults: Cognitive and Psychosocial Factors Open
This paper presents baseline results from a longitudinal study funded by National Institute on Aging examining financial exploitation (FE) among 720 White, African-American, and Hispanic adults age 60 and older. Our proposed conceptual mod…
View article: Racial/ethnic and gender disparities in the use of erythropoiesis-stimulating agents and blood transfusions: cancer management under Medicare’s reimbursement policy
Racial/ethnic and gender disparities in the use of erythropoiesis-stimulating agents and blood transfusions: cancer management under Medicare’s reimbursement policy Open
BACKGROUND: Because of increasing safety concerns related to erythropoiesisstimulating agents (ESAs), the Centers for Medicare & Medicaid Services issued a Medicare reimbursement policy change regarding these medications in cancer patients…
View article: Predictors of Patient Portal Use Among Community-Dwelling Older Adults
Predictors of Patient Portal Use Among Community-Dwelling Older Adults Open
Older adults lag behind their younger counterparts in the use of patient portals, which may limit their ability to engage in health care. A better understanding of the factors associated with portal use among older adults is needed. We exa…
View article: Improving Support for Family Caregivers of People with a Serious Illness in the United States: Strategic Agenda and Call to Action
Improving Support for Family Caregivers of People with a Serious Illness in the United States: Strategic Agenda and Call to Action Open
Background: An estimated 30% of the adult American population are caregivers and many of the people they support live with serious illnesses. Caregivers provide an average of 20 hours of services per week and are heavily involved in assist…
View article: Family Caregiving for Older Adults
Family Caregiving for Older Adults Open
Family members are the primary source of support for older adults with chronic illness and disability. Thousands of published empirical studies and dozens of reviews have documented the psychological and physical health effects of caregivi…
View article: FINANCIAL EXPLOITATION OF OLDER ADULTS: PRELIMINARY RESULTS FROM A PROSPECTIVE LONGITUDINAL STUDY
FINANCIAL EXPLOITATION OF OLDER ADULTS: PRELIMINARY RESULTS FROM A PROSPECTIVE LONGITUDINAL STUDY Open
This paper presents study design and preliminary results from a new study funded by the National Institute on Aging that is examining financial exploitation (FE) among 720 White, African-American and Hispanic adults age 60+ (240 per group;…
View article: WHITE MATTER INTEGRITY UNDERLYING SUBSYNDROMAL DEPRESSION SYMPTOMS IN DEMENTIA CAREGIVERS
WHITE MATTER INTEGRITY UNDERLYING SUBSYNDROMAL DEPRESSION SYMPTOMS IN DEMENTIA CAREGIVERS Open
Past research shows that major depression is associated with lower white matter integrity in fronto-limbic and other areas. But it is not known whether the integrity of these white matter connections is associated with subsyndromal depress…
View article: Activity patterns related to depression symptoms in stressed dementia caregivers
Activity patterns related to depression symptoms in stressed dementia caregivers Open
These novel findings suggest that morning activity may protect dCGs from depression symptoms. Future studies should test whether helping dCGs get active in the morning influences the other features of depression in this population (i.e. in…
View article: Gender differences in short-term cardiovascular effects of giving and receiving support for health concerns in marriage.
Gender differences in short-term cardiovascular effects of giving and receiving support for health concerns in marriage. Open
Receiving support individually may be more important than receiving support mutually for older adult spouses coping with their health concerns. Also, support interventions for couples coping with health conditions should take into account …
View article: Joint modeling of bivariate longitudinal and survival data in spouse pairs
Joint modeling of bivariate longitudinal and survival data in spouse pairs Open
We investigated the association between longitudinally measured depression scores and survival times simultaneously for paired spouse data from the Cardiovascular Health Study (CHS). We propose a joint model incorporating within pair corre…