Richard Weiten
YOU?
Author Swipe
View article: Sexual Medicine and Male InfertilityAltered Endothelin Receptor Expression in Idiopathic Male Infertility: A Potential Therapeutic Target
Sexual Medicine and Male InfertilityAltered Endothelin Receptor Expression in Idiopathic Male Infertility: A Potential Therapeutic Target Open
Objective: Idiopathic male infertility is frequently associated with impaired semen quality, particularly in men diagnosed with oligo-astheno-teratozoospermia (OAT) syn- drome. Recent studies suggest a potential role of the endothelin (ET)…
View article: Cost-Effectiveness Analysis of Perioperative Durvalumab Plus Platin-Based Chemotherapy in Muscle Invasive Bladder Cancer
Cost-Effectiveness Analysis of Perioperative Durvalumab Plus Platin-Based Chemotherapy in Muscle Invasive Bladder Cancer Open
View article: Cost-effectiveness Analysis in the New Era of Treatment Strategies in Metastatic Urothelial Carcinoma Based on Checkmate-901 and EV302/Keynote-A39
Cost-effectiveness Analysis in the New Era of Treatment Strategies in Metastatic Urothelial Carcinoma Based on Checkmate-901 and EV302/Keynote-A39 Open
This report presents a cost-effectiveness analysis of emerging treatment options for metastatic urothelial carcinoma. The combination of enfortumab vedotin + pembrolizumab emerged as the most effective treatment; however, it also proved to…
View article: Among renal cell carcinoma subtypes, only papillary renal cell carcinoma demonstrated relevant TROP-2 positivity as a rationale for antibody-drug conjugates targeting TROP-2
Among renal cell carcinoma subtypes, only papillary renal cell carcinoma demonstrated relevant TROP-2 positivity as a rationale for antibody-drug conjugates targeting TROP-2 Open
Objective To evaluate the expression of trophoblast cell surface antigen-2 (TROP-2), a broadly expressed antibody-drug conjugate (ADC) target, in non-clear cell renal cell carcinoma (non-ccRCC) and to conduct a proof-of-concept analysis as…
View article: Trophoblast cell surface antigen‐2: a promising new biomarker and potential therapeutic target in penile squamous cell carcinoma
Trophoblast cell surface antigen‐2: a promising new biomarker and potential therapeutic target in penile squamous cell carcinoma Open
Objective To evaluate the potential utility of antibody‐drug conjugates targeting trophoblast cell surface antigen‐2 (TROP‐2) in patients with primary penile squamous cell carcinoma (PSCC), patients with recurrence (REC cohort), and patien…
View article: Key learnings from concordant systematic biopsies in prostate‐specific membrane antigen positron emission tomography/computed tomography‐guided prostate biopsies: Enhancing targeting accuracy
Key learnings from concordant systematic biopsies in prostate‐specific membrane antigen positron emission tomography/computed tomography‐guided prostate biopsies: Enhancing targeting accuracy Open
Background Prostate cancer (PCa) diagnosis and staging have evolved with the advent of 68Ga‐Prostate‐specific membrane antigen positron emission tomography/computed tomography (PSMA‐PET/CT). This study investigates the role of complementar…
View article: Current role of systematic biopsy in diagnosis of clinically significant prostate cancer in primary combined MRI-targeted biopsy: a high-volume single-center study
Current role of systematic biopsy in diagnosis of clinically significant prostate cancer in primary combined MRI-targeted biopsy: a high-volume single-center study Open
View article: Increased Severe Adverse Outcomes and Decreased Emergency Room Visits for Pyelonephritis: First Report of Collateral Damage during COVID-19 Pandemic in Urology
Increased Severe Adverse Outcomes and Decreased Emergency Room Visits for Pyelonephritis: First Report of Collateral Damage during COVID-19 Pandemic in Urology Open
Purpose: The coronavirus disease 2019 (COVID-19) pandemic is disrupting urology health-care worldwide. Reduced emergency room visits resulting in adverse outcomes have most recently been reported in pediatrics and cardiology.…
View article: The knockdown of the Mediator complex subunit MED15 restrains urothelial bladder cancer cells' malignancy
The knockdown of the Mediator complex subunit MED15 restrains urothelial bladder cancer cells' malignancy Open
The Mediator complex, a multi-subunit protein complex, plays an integral role in regulating transcription. Genetic alterations of the mediator subunit 15 (MED15) in separate tumor entities have been described previously. However, till now,…
View article: The Mediator complex subunit MED15, a promoter of tumour progression and metastatic spread in renal cell carcinoma
The Mediator complex subunit MED15, a promoter of tumour progression and metastatic spread in renal cell carcinoma Open
The research concludes that MED15 does seem to play a tumour promoting role in the progression and metastatic spread of renal cell carcinoma.
View article: The Contrasting Role of the Mediator Subunit MED30 in the Progression of Bladder Cancer
The Contrasting Role of the Mediator Subunit MED30 in the Progression of Bladder Cancer Open
MED30 appears to be integrated in the progression of the urothelial tumour in the bladder.