Richella Ryan
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View article: 17 Optimising palliative care assessment: a quality improvement project on IPOS integration during hospice admissions
17 Optimising palliative care assessment: a quality improvement project on IPOS integration during hospice admissions Open
Background The Integrated Palliative care Outcome Scale (IPOS) is an important tool for patient care in the palliative setting. Consistent evidence shows that it facilitates comprehensive assessment, improves symptom management, and foster…
View article: 170 Clinical characteristics and risk factors for distress amongst hospice inpatients needing Phenobarbital for deep sedation at the end of life: a single-site service evaluation
170 Clinical characteristics and risk factors for distress amongst hospice inpatients needing Phenobarbital for deep sedation at the end of life: a single-site service evaluation Open
Background Terminal agitation is a common symptom in the last days of life which is usually manageable using standard measures. In rare circumstances, it's necessary to use Phenobarbital. This service evaluation aimed to describe the chara…
View article: 134 Restructuring the hospice MDT meeting: what do hospice healthcare professionals want and need from their MDT meetings?
134 Restructuring the hospice MDT meeting: what do hospice healthcare professionals want and need from their MDT meetings? Open
Background Multidisciplinary team (MDT) meetings are important in various specialties to ensure organised and collaborative care for patients. In palliative care, the MDT includes but is not limited to doctors, nurses, therapists, psycholo…
View article: Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease
Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease Open
Importance Chronic breathlessness is common in people with chronic obstructive pulmonary disease (COPD). Regular, low-dose, extended-release morphine may relieve breathlessness, but evidence about its efficacy and dosing is needed. Objecti…
View article: Anticipatory syringe pumps: benefits and risks
Anticipatory syringe pumps: benefits and risks Open
We welcome the Association of Supportive and Palliative Care Pharmacy’s (ASPCP) recent position statement that the perceived benefit of the anticipatory prescribing of a syringe pump (driver) does not outweigh potential risks.1 This is an …
View article: Anticipatory prescribing in community end-of-life care in the UK and Ireland during the COVID-19 pandemic: online survey
Anticipatory prescribing in community end-of-life care in the UK and Ireland during the COVID-19 pandemic: online survey Open
Background Anticipatory prescribing (AP) of injectable medications in advance of clinical need is established practice in community end-of-life care. Changes to prescribing guidelines and practice have been reported during the COVID-19 pan…
View article: 82 Anticipatory prescribing in community end of life care in the UK: a mixed-methods study of healthcare professionals’ views concerning best practice and areas in need of improvement
82 Anticipatory prescribing in community end of life care in the UK: a mixed-methods study of healthcare professionals’ views concerning best practice and areas in need of improvement Open
Introduction Anticipatory prescribing (AP), the supply of injectable medication to a patient in advance of need, is well-established practice in the UK although there is currently limited evidence and guidance to support best practice. Wit…
View article: 11 How is anticipatory prescribing in community end of life care governed in the UK? A content analysis of national and local guidance documents
11 How is anticipatory prescribing in community end of life care governed in the UK? A content analysis of national and local guidance documents Open
Introduction Anticipatory prescribing (AP) in end of life care is a complex process consisting of at least 5 sequential phases: 1) decision to prescribe, 2) prescribing and dispensing, 3) set-up, storage and monitoring, 4) assessment and a…
View article: Anticipatory syringe drivers: a step too far
Anticipatory syringe drivers: a step too far Open
The recent Gosport War Memorial Hospital inquiry1 has increased UK patient, public and clinician awareness about syringe drivers for continuous subcutaneous delivery of opioids and other medications at the end of life.2 3 The inquiry found…
View article: 49 A UK-wide service evaluation of documents relating to anticipatory prescribing at the end of life
49 A UK-wide service evaluation of documents relating to anticipatory prescribing at the end of life Open
Background Anticipatory Prescribing (AP), or 'Just in Case' prescribing ahead of need, is a well-established component of end of life care in the UK. It aims to facilitate effective symptom control in the home and care home setting and red…
View article: Anticipatory prescribing of injectable medications for adults at the end of life in the community: A systematic literature review and narrative synthesis
Anticipatory prescribing of injectable medications for adults at the end of life in the community: A systematic literature review and narrative synthesis Open
Background: The anticipatory prescribing of injectable medications to provide end-of-life symptom relief is an established community practice in a number of countries. The evidence base to support this practice is unclear. Aim: To review t…
View article: An NT5E Gene Polymorphism Associates with Low Bone Mineral Density in Chronic Kidney Disease Patients
An NT5E Gene Polymorphism Associates with Low Bone Mineral Density in Chronic Kidney Disease Patients Open
Arterial calcification is an independent predictor of all-cause and cardiovascular mortality in end-stage renal disease.CD73, a GPI-linked plasma membrane ecto-enzyme encoded by NT5E gene, is involved in vascular calcification inhibition.M…
View article: 58 Anticipatory prescribing practice at a district general hospital: a service evaluation
58 Anticipatory prescribing practice at a district general hospital: a service evaluation Open
Background NICE guidelines (NG31, 2015) advise that suitable anticipatory medicines (AMs) are prescribed as early as possible for people likely to need symptom control in the last days of life. To date, there has been limited evaluation of…
View article: Anticipatory prescribing of injectable medications for adults at the end of life in the community: A systematic literature review and narrative synthesis
Anticipatory prescribing of injectable medications for adults at the end of life in the community: A systematic literature review and narrative synthesis Open
Background:The anticipatory prescribing of injectable medications to provide end-of-life symptom relief is an established community practice in a number of countries. The evidence base to support this practice is unclear.Aim:To review the …
View article: Breathlessness and inflammation: potential relationships and implications
Breathlessness and inflammation: potential relationships and implications Open
Purpose of review Breathlessness and chronic inflammation both span a wide range of disease contexts and hold prognostic significance. The possibility of a causal relationship between the two has been hypothesized. The aims of this article…
View article: Use of Salivary Diurnal Cortisol as an Outcome Measure in Randomised Controlled Trials: a Systematic Review
Use of Salivary Diurnal Cortisol as an Outcome Measure in Randomised Controlled Trials: a Systematic Review Open
Salivary diurnal cortisol is measured inconsistently across RCTs, which is limiting the interpretation of findings within and across studies. This indicates a need for more validation work, along with consensus guidelines.
View article: What's trending in breathlessness research? Proceedings from the 8th Annual Meeting of the Breathlessness Research Interest Group
What's trending in breathlessness research? Proceedings from the 8th Annual Meeting of the Breathlessness Research Interest Group Open
Breathlessness remains a challenging symptom, common to a multitude of malignant and non-malignant diseases, for which there are limited effective therapies once disease control is optimized. The American Thoracic Society (ATS) statement o…