Rie Karasawa
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View article: POS0421 GLUCOSE TRANSPORTER 1 REGULATES MECHANICAL STRESS-ACTIVATED SUBCHONDRAL BONE FORMATION VIA THE SIGNAL TRANSDUCTION NETWORK OF CELLULAR ENERGY SENSOR, NAD+-DEPENDENT DEACETYLASE (SIRTUIN 1) AND OSTEOGENIC TRANSCRIPTION FACTOR, RUNT-RELATED TRANSCRIPTION FACTOR 2 (RUNX2), IN SUBCHONDRAL BONE TISSUE
POS0421 GLUCOSE TRANSPORTER 1 REGULATES MECHANICAL STRESS-ACTIVATED SUBCHONDRAL BONE FORMATION VIA THE SIGNAL TRANSDUCTION NETWORK OF CELLULAR ENERGY SENSOR, NAD+-DEPENDENT DEACETYLASE (SIRTUIN 1) AND OSTEOGENIC TRANSCRIPTION FACTOR, RUNT-RELATED TRANSCRIPTION FACTOR 2 (RUNX2), IN SUBCHONDRAL BONE TISSUE Open
View article: Association of anti-TPM4 autoantibodies with vasculopathic cutaneous manifestations in juvenile dermatomyositis
Association of anti-TPM4 autoantibodies with vasculopathic cutaneous manifestations in juvenile dermatomyositis Open
Objectives AECAs are detected in multiple forms of vasculitis or vasculopathy, including JDM. High levels of tropomyosin alpha-4 chain (TPM4) gene expression in cutaneous lesions and TPM4 protein expression in some endothelial cells (ECs) …
View article: Association of anti-HSC70 autoantibodies with cutaneous ulceration and severe disease in juvenile dermatomyositis
Association of anti-HSC70 autoantibodies with cutaneous ulceration and severe disease in juvenile dermatomyositis Open
Objectives JDM is an inflammatory myopathy characterized by prominent vasculopathy. AECAs are frequently detected in inflammatory and autoimmune diseases. We sought to determine whether AECAs correlate with clinical features of JDM, and th…
View article: Plasma exosomes from children with juvenile dermatomyositis are taken up by human aortic endothelial cells and are associated with altered gene expression in those cells
Plasma exosomes from children with juvenile dermatomyositis are taken up by human aortic endothelial cells and are associated with altered gene expression in those cells Open
View article: 020. IDENTIFICATION OF TARGET ANTIGENS FOR ANTI-ENDOTHELIAL CELL ANTIBODIES IN PATIENTS WITH TAKAYASU’S ARTERITIS USING PROTEOMICS
020. IDENTIFICATION OF TARGET ANTIGENS FOR ANTI-ENDOTHELIAL CELL ANTIBODIES IN PATIENTS WITH TAKAYASU’S ARTERITIS USING PROTEOMICS Open
cytoplasmic antibody (ANCA) is with ANCA-associated vasculitis the presence of anti-(ANETA) in patients with type of AAV.However, the in MPA remain unknown.or absence of ANETA in the sera y indirect immunofluorescence.igated the NET induct…
View article: Plasma exosomes from children with juvenile dermatomyositis are taken up by human aortic endothelial cells and are associated with altered gene expression in those cells
Plasma exosomes from children with juvenile dermatomyositis are taken up by human aortic endothelial cells and are associated with altered gene expression in those cells Open
Background The pathology of juvenile dermatomyositis (JDM) is characterized by prominent vessel wall and perivascular inflammation. This feature of the disease has remained unexplained and under-investigated. We have hypothesized that plas…
View article: Effects of Low-Level Laser Therapy on Clinical Characteristics and Laboratory Profiles in Synovitis in patients with Rheumatoid Arthritis
Effects of Low-Level Laser Therapy on Clinical Characteristics and Laboratory Profiles in Synovitis in patients with Rheumatoid Arthritis Open
Rheumatoid arthritis (RA) is a chronic disease that requires long-term administration of immunomodulatory drugs, resulting in a greater risk of side effects such as serious infections, malignancies, hepatic or renal dysfunction and cardiov…
View article: Multiple target autoantigens on endothelial cells identified in juvenile dermatomyositis using proteomics
Multiple target autoantigens on endothelial cells identified in juvenile dermatomyositis using proteomics Open
Children with JDM express antibodies to autoantigens in endothelial cells. The clinical and pathological significance of such autoantibodies require further investigation.
View article: Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting
Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting Open
View article: Water-soluble C60-(OH)24 fullerene hydroxide as a therapeutic agent against the degeneration of articular cartilage in osteoarthritis
Water-soluble C60-(OH)24 fullerene hydroxide as a therapeutic agent against the degeneration of articular cartilage in osteoarthritis Open
View article: Using proteomic and genomic methods to understand JDM
Using proteomic and genomic methods to understand JDM Open
Juvenile dermatomyositis is a complex illness characterized by vascular/perivascular inflammation, primarily in the skin and muscles. In this review, we discuss how proteomic and genomic technologies have expanded our understanding of the …