Explanipedia

Assessing social cognition and risk-taking behaviour in patients with young-onset dementia: Study protocol for the YOD-RiSoCo observational prospective cohort study Open

Floor Gelmers, Rients B. Huitema, Myrthe E. Scheenen, Barbara C. Van Munster, Jacoba M. Spikman · 2025

Background Certain subtypes of young onset dementia (YOD), such as the behavioural variant of FTD or the behavioural variant of AD (bvYOD), present with changes in social behaviour instead of memory impairments. These symptoms are often un…

Profile of impairments in social and non-social cognition in vascular dementia compared to Alzheimer’s disease and behavioral variant frontotemporal dementia Open

Fijanne Strijkert, Rients B. Huitema, Barbara C. Van Munster, Jacoba M. Spikman · 2025

Objective: Impairments in emotion recognition, a crucial component of social cognition, have been previously demonstrated in patients with behavioral variant frontotemporal dementia (bv-FTD) and Alzheimer’s disease (AD). However, to date, …

Comment on: “Neuropsychiatric Presentations of Common Dementia Syndromes: A Concise Review for Primary Care Team Members” Open

Fijanne Strijkert, Myrthe E. Scheenen, Rients B. Huitema, Esther van den Berg, Barbara C van Munster , et al. · 2025

Assessing the Validity of Diffusion Weighted Imaging Models: A Study in Patients with Post-Surgical Lower-Grade Glioma Open

Anouk van der Hoorn, Lesley E. Manusiwa, Hiska L. van der Weide, Peter F. Sinnige, Rients B. Huitema , et al. · 2025

Background: Diffusion weighted imaging (DWI) is used for monitoring purposes for lower-grade glioma (LGG). While the apparent diffusion coefficient (ADC) is clinically used, various DWI models have been developed to better understand the m…

Visual feature processing in a large stroke cohort: evidence against modular organization Open

Selma Lugtmeijer, Alicja Sobolewska, Anouk R Smits, Ben Schmand, Edward H.F. de Haan , et al. · 2025

Mid-level visual processing represents a crucial stage between basic sensory input and higher-level object recognition. The conventional model posits that fundamental visual qualities, such as colour and motion, are processed in specialize…

P01.09.A THE NEUROCOGNITIVE FUNCTIONING OF LOWER GRADE GLIOMA PATIENTS BEFORE START OF RADIOTHERAPY IS ASSOCIATED WITH THE RADIOLOGICAL APPEARANCE OF THE BRAIN Open

Hiska L. van der Weide, Miranda C.A. Kramer, F F Siebenga, Johannes A. Langendijk, A. Bannink , et al. · 2023

BACKGROUND The cause for neurocognitive function (NCF) impairments in patients with lower grade glioma (LGG) is typically multifactorial. The aim of this study was to explore the relationship between NCF and the radiological appearance of …

Impaired Emotion Recognition: A Potential Marker for Social Behavioral Problems in Patients With Amnestic Mild Cognitive Impairment and Early Alzheimer Disease? Open

Fijanne Strijkert, Rients B. Huitema, Barbara C. Van Munster, Jacoba M. Spikman · 2023

Objective: Emotion recognition, an important aspect of social cognition, can be impaired already in early Alzheimer disease dementia and amnestic mild cognitive impairment (aMCI) and may underly social behavioral changes, which can increas…

Clinical relevance of the radiation dose bath in lower grade glioma, a cross-sectional pilot study on neurocognitive and radiological outcome Open

Hiska L. van der Weide, J Kłos, Johannes A. Langendijk, Charlotte L. Brouwer, Peter F. Sinnige , et al. · 2022

Cognitive Impairment in Long-Term Survivors of Testicular Cancer More Than 20 Years after Treatment Open

J. Stelwagen, A.T. Meuleman, Sjoukje Lubberts, Gerrie Steursma, Lara M. Kruyt , et al. · 2021

Background: Impaired cognition can be a late effect after treatment in long-term testicular cancer (TC) survivors, negatively affecting their daily life. However, little data is available beyond 20 years post-treatment. We assessed cogniti…

Measuring emotion recognition: Added value in diagnosing dementia of the Alzheimer’s disease type Open

Fijanne Strijkert, Rients B. Huitema, Jacoba M. Spikman · 2021

Neuropsychological tests, particularly for episodic memory, are used to classify patients in memory clinics. Still, the differential diagnosis between dementia of the Alzheimer’s disease type (Dementia‐AD), mild cognitive impairment (MCI),…

Effect of working four night shifts on driving performance and risk behaviour in traffic of anaesthesiology residents Open

Clemens R. M. Barends, Marleen Wever, Jaap Domburg, G. Wietasch, Rients B. Huitema · 2021

Editor, Residents training to become medical specialists work night shifts on a regular basis. The accompanying sleep–wake pattern has detrimental effects on cognitive functions and task performance.1,2 These effects extend beyond the perf…

Are visual working memory and episodic memory distinct processes? Insight from stroke patients by lesion-symptom mapping Open

Selma Lugtmeijer, Linda Geerligs, F.E. de Leeuw, Edward H.F. de Haan, Roy P. C. Kessels , et al. · 2021

The neural underpinnings of facial emotion recognition in ischemic stroke patients Open

Nils S. van den Berg, Edward H.F. de Haan, Rients B. Huitema, Jacoba M. Spikman · 2021

Deficits in facial emotion recognition occur frequently after stroke, with adverse social and behavioural consequences. The aim of this study was to investigate the neural underpinnings of the recognition of emotional expressions, in parti…

RADT-28. RADIATION DOSE-DEPENDENT LONG-TERM NEUROCOGNITIVE DECLINE IN LOW GRADE GLIOMA PATIENTS: RESULTS OF A CROSS-SECTIONAL STUDY Open

Peter F. Sinnige, Hiske van der Weide, Miranda C.A. Kramer, Roelien H. Enting, Ingeborg Bosma , et al. · 2020

BACKGROUND Radiotherapy is a well-known risk factor for neurocognitive decline in glioma patients. Advanced radiotherapy techniques enable more selective brain irradiation. However, limited data exists on which brain regions are most relev…

Comparing static and dynamic emotion recognition tests: Performance of healthy participants Open

Sara Khosdelazad, Lieke S. Jorna, Skye McDonald, Sandra E. Rakers, Rients B. Huitema , et al. · 2020

Facial expressions have a communicatory function and the ability to read them is a prerequisite for understanding feelings and thoughts of other individuals. Impairments in recognition of facial emotional expressions are frequently found i…

Emotion Recognition and Traffic-Related Risk-Taking Behavior in Patients with Neurodegenerative Diseases Open

Nils S. van den Berg, Fransje E. Reesink, Edward H.F. de Haan, H.P.H. Kremer, Jacoba M. Spikman , et al. · 2020

Objectives: Neurodegenerative diseases (NDDs), such as Alzheimer’s disease, frontotemporal dementia, dementia with Lewy bodies, and Huntington’s disease, inevitably lead to impairments in higher-order cognitive functions, including the per…

Driving Performance in Patients With Idiopathic Cervical Dystonia; A Driving Simulator Pilot Study Open

J. van den Dool, Bart Visser, Rients B. Huitema, Simone R. Caljouw, Marina A.J. Tijssen · 2020

Objective: To explore driving performance and driving safety in patients with cervical dystonia (CD) on a simulated lane tracking, intersections and highway ride and to compare it to healthy controls. Design: This study was p…

Impairments in Emotion Recognition and Risk-Taking Behavior After Isolated, Cerebellar Stroke Open

Nils S. van den Berg, Rients B. Huitema, Jacoba M. Spikman, Gert-Jan Luijckx, Edward H.F. de Haan · 2020

A shrunken world – micropsia after a right occipito-parietal ischemic stroke Open

Nils S. van den Berg, Rients B. Huitema, Jacoba M. Spikman, Peter Jan van Laar, Edward H.F. de Haan · 2019

Micropsia is a rare condition in which patients perceive the outside world smaller in size than it actually is. We examined a patient who, after a right occipito-parietal stroke, subjectively reported perceiving everything at seventy perce…

F36 Are social cognitive deficits a predictor for the onset of huntington’s disease? Open

Maxime Vos, Meike Herben-Dekker, Jacoba M. Spikman, Berry Kremer, Rients B. Huitema · 2018

Background The clinical diagnosis of Huntington's disease (HD) is based on motor symptoms, although these can be preceded by cognitive changes. However, it is still difficult to predict the clinical onset of HD based on neuropsychological …

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