Rik Schalbroeck
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View article: Is the Time Right to Start Testing if Late-Onset Depression is Associated With the Development of an α-Synucleinopathy Like Parkinson’s Disease? A Double Systematic Review and Meta-Analysis
Is the Time Right to Start Testing if Late-Onset Depression is Associated With the Development of an α-Synucleinopathy Like Parkinson’s Disease? A Double Systematic Review and Meta-Analysis Open
Parkinson's disease (PD) is characterized by two neurobiological markers: pathological α-synuclein and/or a dopaminergic deficit. Depression is common in PD, and may precede motor signs, particularly in late-onset depression (LOD). We cond…
View article: Access to services for autistic people across Europe
Access to services for autistic people across Europe Open
Background Autistic communities in Europe continue to face difficulties accessing services despite increasing rates of autism diagnosis in recent years. Methods To investigate autistic people’s access to services in Europe and reasons for …
View article: Childhood Trauma As a Mediator of the Association Between Autistic Traits and Psychotic Experiences: Evidence From the Avon Longitudinal Study of Parents and Children Cohort
Childhood Trauma As a Mediator of the Association Between Autistic Traits and Psychotic Experiences: Evidence From the Avon Longitudinal Study of Parents and Children Cohort Open
Background Little is known on whether associations between childhood autistic traits and psychotic experiences persist into adulthood and whether genetic confounding and childhood trauma influence them. Here we investigate the associations…
View article: Cerebral [18F]-FDOPA Uptake in Autism Spectrum Disorder and Its Association with Autistic Traits
Cerebral [18F]-FDOPA Uptake in Autism Spectrum Disorder and Its Association with Autistic Traits Open
Dopaminergic signaling is believed to be related to autistic traits. We conducted an exploratory 3,4-dihydroxy-6-[18F]-fluoro-L-phenylalanine positron emission tomography/computed tomography ([18F]-FDOPA PET/CT) study, to examine cerebral …
View article: Childhood trauma as a mediator of the association between autistic traits and psychotic experiences: evidence from the ALSPAC birth cohort
Childhood trauma as a mediator of the association between autistic traits and psychotic experiences: evidence from the ALSPAC birth cohort Open
Introduction: There is increasing evidence that autistic traits are associated with psychotic experiences. However, the mechanisms underlying such associations are still unknown. In this longitudinal birth cohort study, we examine the rela…
View article: Orderly chaos
Orderly chaos Open
Autistic individuals are widely exposed to socially adverse events, such as social exclusion, bullying, and trauma. The social defeat hypothesis of schizophrenia predicts that these socially defeating experiences increase striatal dopamine…
View article: The social defeat hypothesis of schizophrenia: a parsimonious explanation for multiple psychosis risk factors?
The social defeat hypothesis of schizophrenia: a parsimonious explanation for multiple psychosis risk factors? Open
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View article: Risk of non-affective psychotic disorder or bipolar disorder in autism spectrum disorder: a longitudinal register-based study in the Netherlands
Risk of non-affective psychotic disorder or bipolar disorder in autism spectrum disorder: a longitudinal register-based study in the Netherlands Open
Background Individuals with autism spectrum disorder (ASD) appear to be at increased risk of non-affective psychotic disorder (NAPD) and bipolar disorder (BD). However, most previous studies examined the co-occurrence of ASD and NAPD or BD…
View article: O10.4. INCREASED RISKS FOR NON-AFFECTIVE PSYCHOTIC DISORDER AND BIPOLAR DISORDER IN AUTISM SPECTRUM DISORDER
O10.4. INCREASED RISKS FOR NON-AFFECTIVE PSYCHOTIC DISORDER AND BIPOLAR DISORDER IN AUTISM SPECTRUM DISORDER Open
Young adults with autism spectrum disorder (ASD) appear to be at increased risk for non-affective psychotic disorder (NAPD) and bipolar disorder (BD). However, previous studies have mostly examined the co-occurrence of ASD with NAPD and BD…
View article: A Context-Sensing Mobile Phone App (Q Sense) for Smoking Cessation: A Mixed-Methods Study
A Context-Sensing Mobile Phone App (Q Sense) for Smoking Cessation: A Mixed-Methods Study Open
${\bf Background:}$ A major cause of lapse and relapse to smoking during a quit attempt is craving triggered by cues from a smoker's immediate environment. To help smokers address these cue-induced cravings when attempting to quit, we have…