Rina Jiang
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View article: Clinical features and gut microbiota alterations in hypertensive individuals with left ventricular hypertrophy
Clinical features and gut microbiota alterations in hypertensive individuals with left ventricular hypertrophy Open
Objective This study aims to identify potential diagnostic biomarkers for individuals with hypertension and left ventricular hypertrophy (LVH) by characterizing associated clinical features and gut microbiota profiles. Methods Participants…
View article: Folate receptor β performs an immune checkpoint function in activated macrophages
Folate receptor β performs an immune checkpoint function in activated macrophages Open
Monocytes and macrophages are sentinels of the immune system that distinguish themselves from other cells by expressing the beta isoform of the folate receptor (FRβ). Because FRβ does not bind folate until the monocyte/macrophage is expose…
View article: Tumor-specific activation of folate receptor beta enables reprogramming of immune cells in the tumor microenvironment
Tumor-specific activation of folate receptor beta enables reprogramming of immune cells in the tumor microenvironment Open
Folate receptors can perform folate transport, cell adhesion, and/or transcription factor functions. The beta isoform of the folate receptor (FRβ) has attracted considerable attention as a biomarker for immunosuppressive macrophages and my…
View article: Transfer of exosomal microRNA-203-3p from dendritic cells to bone marrow-derived macrophages reduces development of atherosclerosis by downregulating Ctss in mice
Transfer of exosomal microRNA-203-3p from dendritic cells to bone marrow-derived macrophages reduces development of atherosclerosis by downregulating Ctss in mice Open
Dendritic cell-derived exosomes have been proven to be efficient adjuvant options for anti-tumor vaccines in cancer immunotherapy. However, their potency in atherosclerosis remains unclear. Here we summarize the association of microRNA-203…
View article: Duration of Dual Antiplatelet Therapy and Late Stent Thrombosis Following Percutaneous Coronary Intervention with Second-Generation Drug-Eluting Stents: A Simple Meta-Analysis of Randomized Controlled Trials
Duration of Dual Antiplatelet Therapy and Late Stent Thrombosis Following Percutaneous Coronary Intervention with Second-Generation Drug-Eluting Stents: A Simple Meta-Analysis of Randomized Controlled Trials Open
This simple analysis showed no impact of DAPT duration on the occurrence of late and very late stent thrombosis. Similar late and very late stent thrombosis rates were observed with 6-month versus 12-month duration of DAPT use following PC…