Rion Morishita
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View article: Guide to dynamic OCT data analysis
Guide to dynamic OCT data analysis Open
Dynamic optical coherence tomography (DOCT) enhances conventional OCT by providing specific information related to flow dynamics, cell motility, and organelle metabolic activity. These biological phenomena can be detected with varying sens…
View article: Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals
Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals Open
The wavelength and system-resolution dependencies of dynamic optical coherence tomography (DOCT) are investigated experimentally and numerically. Experimental investigations demonstrate significant wavelength dependency for the DOCT values…
View article: Dynamic-OCT simulation framework based on mathematical models of intratissue dynamics, image formation, and measurement noise
Dynamic-OCT simulation framework based on mathematical models of intratissue dynamics, image formation, and measurement noise Open
Dynamic optical coherence tomography (DOCT) enables label-free functional imaging by capturing temporal OCT signal variations caused by intracellular and intratissue motions. However, the relationship between DOCT signals and the sample mo…
View article: Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals
Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals Open
The wavelength and system-resolution dependencies of dynamic optical coherence tomography (DOCT) are investigated experimentally and numerically. Experimental investigations demonstrate significant wavelength dependency for the DOCT values…
View article: In vivo dynamic optical coherence tomography of human skin with hardware- and software-based motion correction
In vivo dynamic optical coherence tomography of human skin with hardware- and software-based motion correction Open
In vivo application of dynamic optical coherence tomography (DOCT) is hindered by bulk motion of the sample. We demonstrate DOCT imaging of \invivo human skin by adopting a sample-fixation attachment to suppress bulk motion and a subsequen…
View article: Dynamic-OCT simulation framework based on mathematical models of intratissue dynamics, image formation, and measurement noise
Dynamic-OCT simulation framework based on mathematical models of intratissue dynamics, image formation, and measurement noise Open
Dynamic optical coherence tomography (DOCT) enables label-free functional imaging by capturing temporal OCT signal variations caused by intracellular and intratissue motions. However, the relationship between DOCT signals and the sample mo…
View article: Dynamic optical coherence tomography algorithm for label-free assessment of swiftness and occupancy of intratissue moving scatterers
Dynamic optical coherence tomography algorithm for label-free assessment of swiftness and occupancy of intratissue moving scatterers Open
Dynamic optical coherence tomography (DOCT) statistically analyzes fluctuations in time-sequential OCT signals, enabling label-free and three-dimensional visualization of intratissue and intracellular activities. Current DOCT methods, such…
View article: Label-free visualization and quantification of the drug-type-dependent response of tumor spheroids by dynamic optical coherence tomography
Label-free visualization and quantification of the drug-type-dependent response of tumor spheroids by dynamic optical coherence tomography Open
We demonstrate label-free dynamic optical coherence tomography (D-OCT)-based visualization and quantitative assessment of patterns of tumor spheroid response to three anti-cancer drugs. The study involved treating human breast adenocarcino…
View article: Label-free visualization and quantification of the drug-type-dependent response of tumor spheroids by dynamic optical coherence tomography
Label-free visualization and quantification of the drug-type-dependent response of tumor spheroids by dynamic optical coherence tomography Open
We demonstrate label-free dynamic optical coherence tomography (D-OCT)-based visualization and quantitative assessment of patterns of tumor spheroid response to three anti-cancer drugs. The study involved treating human breast adenocarcino…
View article: Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging
Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging Open
A new formulation of the lateral imaging process of point-scanning optical coherence tomography (OCT) and a new differential contrast method designed by using this formulation are presented. The formulation is based on a mathematical sampl…
View article: Label-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography
Label-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography Open
An organoid is a three-dimensional (3D) in vitro cell culture emulating human organs. We applied 3D dynamic optical coherence tomography (DOCT) to visualize the intratissue and intracellular activities of human induced pluripotent stem cel…
View article: Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging
Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging Open
A new formulation of lateral imaging process of point-scanning optical coherence tomography (OCT) and a new differential contrast method designed by using this formulation are presented. The formulation is based on a mathematical sample mo…
View article: Label-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography
Label-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography Open
An organoid is a three-dimensional (3D) in vitro cell culture emulating human organs. We applied 3D dynamic optical coherence tomography (DOCT) to visualize the intratissue and intracellular activities of human induced pluripotent stem cel…
View article: Label-free metabolic imaging of non-alcoholic-fatty-liver-disease (NAFLD) liver by volumetric dynamic optical coherence tomography
Label-free metabolic imaging of non-alcoholic-fatty-liver-disease (NAFLD) liver by volumetric dynamic optical coherence tomography Open
Label-free metabolic imaging of non-alcoholic fatty liver disease (NAFLD) mouse liver is demonstrated ex vivo by dynamic optical coherence tomography (OCT). The NAFLD mouse is a methionine choline-deficient (MCD)-diet model, and two mice f…
View article: Label-free metabolic imaging of non-alcoholic-fatty-liver-disease\n (NAFLD) liver by volumetric dynamic optical coherence tomography
Label-free metabolic imaging of non-alcoholic-fatty-liver-disease\n (NAFLD) liver by volumetric dynamic optical coherence tomography Open
Label-free metabolic imaging of non-alcoholic fatty liver disease (NAFLD)\nmouse liver is demonstrated ex vivo by dynamic optical coherence tomography\n(OCT). The NAFLD mouse is a methionine choline-deficient (MCD)-diet model, and\ntwo mic…