Rishi Kumar Jaiswal
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View article: Subtelomeric elements provide stability to short telomeres in telomerase-negative cells of the budding yeast Naumovozyma castellii
Subtelomeric elements provide stability to short telomeres in telomerase-negative cells of the budding yeast Naumovozyma castellii Open
Telomerase plays an important role in sustaining eukaryotic linear chromosomes, as elongation of telomeres is needed to counterbalance the shortening occurring in each replication round. Nevertheless, in telomerase-deficient cells, Alterna…
View article: Editorial: Novel approaches for developing vaccines against influenza virus
Editorial: Novel approaches for developing vaccines against influenza virus Open
Citation: Jaiswal RK and Basu S (2024) Editorial: Novel approaches for developing vaccines against influenza virus. Front. Cell. Infect. Microbiol. 14:1435768. doi: 10.3389/fcimb.2024.1435768
View article: Human CST complex restricts excessive PrimPol repriming upon UV induced replication stress by suppressing p21
Human CST complex restricts excessive PrimPol repriming upon UV induced replication stress by suppressing p21 Open
DNA replication stress, caused by various endogenous and exogenous agents, halt or stall DNA replication progression. Cells have developed diverse mechanisms to tolerate and overcome replication stress, enabling them to continue replicatio…
View article: Role of Immunoglobulin A in COVID-19 and Influenza Infections
Role of Immunoglobulin A in COVID-19 and Influenza Infections Open
Immunoglobulin A (IgA) is critical in the immune response against respiratory infections like COVID-19 and influenza [...]
View article: Challenges In Cancer Immunotherapy
Challenges In Cancer Immunotherapy Open
The concept of deploying the immune system to treat neoplastic diseases emerged in the nineteenth century. It made significant progress in the twentieth century with the advent of new technology. Various immunotherapy treatments exist, inc…
View article: Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair
Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair Open
Despite the high lethality of colorectal cancers (CRCs), only a limited number of genetic risk factors are identified. The mammalian ssDNA-binding protein complex CTC1-STN1-TEN1 protects genome stability, yet its role in tumorigenesis is u…
View article: An assessment of the strategy and status of COVID-19 vaccination in India
An assessment of the strategy and status of COVID-19 vaccination in India Open
The COVID-19 disease continues to cause devastation for almost 3 years of its identification. India is one of the leading countries to set clinical trials, production, and administration of COVID-19 vaccination. Recent COVID-19 vaccine tra…
View article: Children’s SARS-CoV-2 Infection and Their Vaccination
Children’s SARS-CoV-2 Infection and Their Vaccination Open
SARS-CoV-2, a novel coronavirus, causes respiratory tract infections and other complications in affected individuals, and has resulted in numerous deaths worldwide. The unprecedented pace of its transmission worldwide, and the resultant he…
View article: An Assessment of the Bivalent Vaccine as a Second Booster for COVID-19
An Assessment of the Bivalent Vaccine as a Second Booster for COVID-19 Open
In the USA, two monovalent COVID-19 mRNA vaccines are primarily used for vaccination [...]
View article: The telomeric 5′ end nucleotide is regulated in the budding yeast <i>Naumovozyma castellii</i>
The telomeric 5′ end nucleotide is regulated in the budding yeast <i>Naumovozyma castellii</i> Open
The junction between the double-stranded and single-stranded telomeric DNA (ds–ss junction) is fundamental in the maintenance of the telomeric chromatin, as it directs the assembly of the telomere binding proteins. In budding yeast, multip…
View article: SPERMIDINE MAINTAINS TELOMERE LENGTH AND DELAYS AGING
SPERMIDINE MAINTAINS TELOMERE LENGTH AND DELAYS AGING Open
Spermidine, a natural polyamine, has been noticed for its anti-aging properties. Supplementation of this drug prolongs lifespan and diminishes the incidence of age-related pathology. In the human population, spermidine levels decrease as a…
View article: Optical Data Downlinks from OSIRIS on Flying Laptop Satellite
Optical Data Downlinks from OSIRIS on Flying Laptop Satellite Open
Optical High-Speed Telemetry Downlinks for high data volumes from Earth Observation Satellites in Low Earth Orbit (OLEODL) is currently developing into a future standard in high-speed space communications. The German Aerospace Center (DLR)…
View article: Proteomic identification of proteins differentially expressed following overexpression of hTERT (human telomerase reverse transcriptase) in cancer cells
Proteomic identification of proteins differentially expressed following overexpression of hTERT (human telomerase reverse transcriptase) in cancer cells Open
Reverse transcriptase activity of telomerase adds telomeric repeat sequences at extreme ends of the newly replicated chromosome in actively dividing cells. Telomerase expression is not detected in terminally differentiated cells but is not…