Rakesh Bhatnagar
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View article: Comparative Analysis of Bio-Based and Traditional Plastics: Life Cycle Assessment, Cost-Benefit Analysis, and Health Impact Evaluation
Comparative Analysis of Bio-Based and Traditional Plastics: Life Cycle Assessment, Cost-Benefit Analysis, and Health Impact Evaluation Open
This article compares extensively the essential parameters of three important parameters between bio-plastics and their traditional petroleum-based counterparts: life cycle analysis, cost-benefit analysis, and health impact analysis. Given…
View article: Enhancing Database Efficiency: A Comprehensive Approach to DB Lock Optimization
Enhancing Database Efficiency: A Comprehensive Approach to DB Lock Optimization Open
Typically, large-scale data transfers into the database cause lots of locking which negatively affects query execution, concurrency, as well as blocking operations such as ALTER, UPDATE, and DELETE. To ensure data consistency, a set of loc…
View article: A Novel Framework for Resilient Glue Jobs: Mitigating 404 and 429 Errors
A Novel Framework for Resilient Glue Jobs: Mitigating 404 and 429 Errors Open
Resilient Apache Glue Jobs: Mitigating 404 and 429 Errors with Proactive Strategies This research paper examines incident management strategies for Apache Glue Jobs, specifically focusing on mitigating the impact of frequent 404 Not Found …
View article: Differential genome organization revealed by comparative topological analysis of <i>Mycobacterium tuberculosis</i> strains H37Rv and H37Ra
Differential genome organization revealed by comparative topological analysis of <i>Mycobacterium tuberculosis</i> strains H37Rv and H37Ra Open
Recent studies have shown that three-dimensional architecture of bacterial chromatin plays an important role in gene expression regulation. However, genome topological organization in Mycobacterium tuberculosis , the etiologic agent of tub…
View article: ANCIENT SCHWANNOMA AS AN EXCEPTIONAL SACRAL SPINAL TUMOUR: A CASE REPORT
ANCIENT SCHWANNOMA AS AN EXCEPTIONAL SACRAL SPINAL TUMOUR: A CASE REPORT Open
Schwannomas predominantly are non-cancerous tumors that develop from the protective covering of nerves. These growths can occur throughout the body and may lead to issues such as pressure symptoms and aesthetic or functional anomalies, dep…
View article: Identification of genes associated with persistence in Mycobacterium smegmatis
Identification of genes associated with persistence in Mycobacterium smegmatis Open
The prevalence of bacterial persisters is related to their phenotypic diversity and is responsible for the relapse of chronic infections. Tolerance to antibiotic therapy is the hallmark of bacterial persistence. In this study, we have scre…
View article: Impacts of Co and Pb on growth and physiological parameters of Portulaca oleracea (Purslane)
Impacts of Co and Pb on growth and physiological parameters of Portulaca oleracea (Purslane) Open
Portulaca oleracea has tendency to remove heavy metals from the soil as it has phytoremediation properties. This plant has potential to with stand heavy metal stress without getting impacts on normal plant physiology. The aim of this study…
View article: Enrichment of Lactic Acid-Producing Bacteria in the Fecal Microbiota of Patients with Ulcerative Colitis in North India
Enrichment of Lactic Acid-Producing Bacteria in the Fecal Microbiota of Patients with Ulcerative Colitis in North India Open
Previous studies have established the relationship between the gut microbiota and ulcerative colitis (UC); however, there is a scarcity of data on the fecal microbiome profile of patients with UC in the Indian population. This study aimed …
View article: IMMUNOMODULATING, PROPHYLACTIC, AND THERAPEUTIC POTENTIAL OF NATURAL PHAGES IN GANGA WATER
IMMUNOMODULATING, PROPHYLACTIC, AND THERAPEUTIC POTENTIAL OF NATURAL PHAGES IN GANGA WATER Open
The present paper explores the immunomodulating, prophylactic, and therapeutic potential of Ganga water. Ganga water is reported to have 200 isolates of phages which is ten times more than Yamuna and Narmada. This diversity of phages sugge…
View article: Supplementary Figure Legend from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
Supplementary Figure Legend from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer Open
Supplementary Figure Legend from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
View article: Data from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
Data from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer Open
Background: Epidemiologic studies have established that women with prior atypical ductal hyperplastic (ADH) lesions have a 5-fold increased risk of developing invasive breast cancer (IBC). However, there is currently no means of identifyin…
View article: Supplementary Figure Legend from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
Supplementary Figure Legend from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer Open
Supplementary Figure Legend from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
View article: Supplementary Figure 1 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
Supplementary Figure 1 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer Open
Supplementary Figure 1 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
View article: Supplementary Tables 1-5 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
Supplementary Tables 1-5 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer Open
Supplementary Tables 1-5 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
View article: Supplementary Figure 1 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
Supplementary Figure 1 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer Open
Supplementary Figure 1 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
View article: Supplementary Tables 1-5 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
Supplementary Tables 1-5 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer Open
Supplementary Tables 1-5 from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
View article: Data from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer
Data from Expression of Carcinoembryonic Antigen Cell Adhesion Molecule 6 Oncoprotein in Atypical Ductal Hyperplastic Tissues Is Associated with the Development of Invasive Breast Cancer Open
Background: Epidemiologic studies have established that women with prior atypical ductal hyperplastic (ADH) lesions have a 5-fold increased risk of developing invasive breast cancer (IBC). However, there is currently no means of identifyin…
View article: Recombinant full-length Bacillus Anthracis protective antigen and its 63 kDa form elicits protective response in formulation with addavax
Recombinant full-length Bacillus Anthracis protective antigen and its 63 kDa form elicits protective response in formulation with addavax Open
Introduction Bacillus anthracis is the causative agent for the lethal disease anthrax, primarily affecting animals and humans in close contact with an infected host. The pathogenicity of B. anthracis is attributed to the secreted exotoxins…
View article: Homology modelling and molecular simulation approach to prediction of B-cell and T-cell epitopes in an OMP25 peptide vaccine against <i>Brucella abortus</i>
Homology modelling and molecular simulation approach to prediction of B-cell and T-cell epitopes in an OMP25 peptide vaccine against <i>Brucella abortus</i> Open
The live attenuated vaccine composition against brucellosis poses potential risks to recipient animals. Therefore, we have analysed an in-silico approach to design a novel multi-epitope vaccine peptide to elicit a desirable immune response…
View article: High Throughput Chromosome Conformation Capture identifies differential genome organization in virulent and avirulent strains of<i>Mycobacterium tuberculosis</i>
High Throughput Chromosome Conformation Capture identifies differential genome organization in virulent and avirulent strains of<i>Mycobacterium tuberculosis</i> Open
Recent studies have shown that three-dimensional architecture of bacterial chromatin plays an important role in gene expression regulation. However, genome topological organization in Mycobacterium tuberculosis (M. tuberculosis) , the etio…
View article: PREVALENCE OF POSITIVITY OF CBNAAT IN EXTRA PULMONARY TUBERCULOSIS
PREVALENCE OF POSITIVITY OF CBNAAT IN EXTRA PULMONARY TUBERCULOSIS Open
Background: TB is the 9th leading cause of death worldwide and the leading cause from a single infectious agent. It is estimated that 15 to 20% of all TB cases are extra pulmonary.
Methods: This study conducted on Patients of EPTB diagnos…
View article: PREVALENCE OF POSITIVITY OF CBNAAT IN PULMONARY TUBERCULOSIS
PREVALENCE OF POSITIVITY OF CBNAAT IN PULMONARY TUBERCULOSIS Open
Background: TB Is the ninth leading cause of death worldwide and the leading cause from a single infectious agent, ranking above HIV/AIDS. In 2016, there were an estimated 1.3 million TB deaths among HIV negative people (down from 1.7 mill…
View article: Network analysis of host-pathogen protein interactions in microbe induced cardiovascular diseases
Network analysis of host-pathogen protein interactions in microbe induced cardiovascular diseases Open
Large-scale visualization and analysis of HPIs involved in microbial CVDs can provide crucial insights into the mechanisms of pathogenicity. The comparison of CVD associated HPIs with the entire set of HPIs can identify the pathways specif…
View article: A clickable folic acid-rhamnose conjugate for selective binding to cancer cells
A clickable folic acid-rhamnose conjugate for selective binding to cancer cells Open
Specific cell surface receptors present in abundance on tumor cells have been used for targeted therapies of antibodies. Antibody based therapies involving antibody recruiting molecules (ARM) for treatment of cancer are selective and have …
View article: Correlation between faecal microbial taxa and ulcerative colitis in different phases of disease activity in a north Indian cohort
Correlation between faecal microbial taxa and ulcerative colitis in different phases of disease activity in a north Indian cohort Open
Background and Aims A link between gut microbiota and Ulcerative colitis (UC) has been established in several studies. However, only a few studies have examined specific changes in microbiota associated with different phases of disease act…
View article: Insights into the molecular determinants involved in <i>Mycobacterium tuberculosis</i> persistence and their therapeutic implications
Insights into the molecular determinants involved in <i>Mycobacterium tuberculosis</i> persistence and their therapeutic implications Open
The establishment of persistent infections and the reactivation of persistent bacteria to active bacilli are the two hurdles in effective tuberculosis treatment. Mycobacterium tuberculosis, an etiologic tuberculosis agent, adapts to numero…
View article: Observational case studies of treatment of skin disorders with natural phages in Ganga water
Observational case studies of treatment of skin disorders with natural phages in Ganga water Open
Background: Skin conditions have multiple causes. Natural phages in the Ganga River have bactericidal qualities against a number of bacterial infections, which help resolve skin conditions. Materials and Methods: We collected water from up…
View article: Zur: Zinc-Sensing Transcriptional Regulator in a Diverse Set of Bacterial Species
Zur: Zinc-Sensing Transcriptional Regulator in a Diverse Set of Bacterial Species Open
Zinc (Zn) is the quintessential d block metal, needed for survival in all living organisms. While Zn is an essential element, its excess is deleterious, therefore, maintenance of its intracellular concentrations is needed for survival. The…
View article: Structure-based drug repurposing to inhibit the DNA gyrase of <i>Mycobacterium tuberculosis</i>
Structure-based drug repurposing to inhibit the DNA gyrase of <i>Mycobacterium tuberculosis</i> Open
Drug repurposing is an alternative avenue for identifying new drugs to treat tuberculosis (TB). Despite the broad-range of anti-tubercular drugs, the emergence of multi-drug-resistant and extensively drug-resistant strains of Mycobacterium…