Rivka Adar
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View article: GMP-like and MLP-like Subpopulations of Hematopoietic Stem and Progenitor Cells Harboring Mutated EZH2 and TP53 at Diagnosis Promote Acute Myeloid Leukemia Relapse: Data of Combined Molecular, Functional, and Genomic Single-Stem-Cell Analyses
GMP-like and MLP-like Subpopulations of Hematopoietic Stem and Progenitor Cells Harboring Mutated EZH2 and TP53 at Diagnosis Promote Acute Myeloid Leukemia Relapse: Data of Combined Molecular, Functional, and Genomic Single-Stem-Cell Analyses Open
Acute myeloid leukemia (AML) is associated with unfavorable patient outcomes primarily related to disease relapse. Since specific types of leukemic hematopoietic stem and progenitor cells (HSPCs) are suggested to contribute to AML propagat…
View article: Retrospective cell lineage reconstruction in Humans using short tandem repeats
Retrospective cell lineage reconstruction in Humans using short tandem repeats Open
Cell lineage analysis aims to uncover the developmental history of an organism back to its cell of origin 1 . Recently, novel in vivo methods and technologies utilizing genome editing enabled important insights into the cell lineages of an…
View article: Comparison of seven single cell Whole Genome Amplification commercial kits using targeted sequencing
Comparison of seven single cell Whole Genome Amplification commercial kits using targeted sequencing Open
Advances in biochemical technologies have led to a boost in the field of single cell genomics. Observation of the genome at a single cell resolution is currently achieved by pre-amplification using whole genome amplification (WGA) techniqu…
View article: A generic, cost-effective, and scalable cell lineage analysis platform
A generic, cost-effective, and scalable cell lineage analysis platform Open
Advances in single-cell genomics enable commensurate improvements in methods for uncovering lineage relations among individual cells. Current sequencing-based methods for cell lineage analysis depend on low-resolution bulk analysis or rely…