Robben Schat
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View article: Case Report: Deep and durable response to talazoparib in germline BRCA2-mutated rectal neuroendocrine carcinoma
Case Report: Deep and durable response to talazoparib in germline BRCA2-mutated rectal neuroendocrine carcinoma Open
High-grade neuroendocrine carcinoma (NEC) of the rectum is a rare and aggressive malignancy, with limited treatment options and a poor prognosis. We report the successful off-label use of the PARP inhibitor talazoparib in a patient with me…
Synchronous Succinate Dehydrogenase Subunit B (SDHB)-Deficient Gallbladder Paraganglioma and Periduodenal Well-Differentiated Neuroendocrine Tumor: A Case Report Open
Paragangliomas are extra-adrenal neuroendocrine neoplasms (NENs), and those arising in the gallbladder are exceedingly rare. Pathogenic variants in the succinate dehydrogenase (SDH) complex are well-established drivers of paragangliomas an…
View article: Case Report: Metastatic small bowel adenocarcinoma with DNA mismatch repair deficiency in an organ transplant recipient treated with anti-PD-1 immunotherapy
Case Report: Metastatic small bowel adenocarcinoma with DNA mismatch repair deficiency in an organ transplant recipient treated with anti-PD-1 immunotherapy Open
We present a case of a 65-year-old woman with a history of kidney and pancreas transplants for type 1 diabetes mellitus who presented with small bowel obstruction and was found to have a poorly differentiated small bowel adenocarcinoma wit…
Surgical microwave ablation for multifocal non-resectable liver metastases: a single institution experience treating five or more liver lesions Open
Thermal ablation can provide acceptable DFS and OS, even with high volume metastatic colorectal cancers. Future efforts should be focused on defining selection criteria for those most likely to benefit from this aggressive approach.
Impact of 18-French Rectal Tube Placement on Image Quality of Multiparametric Prostate MRI Open
This study compared prostate multiparametric MRI (mpMRI) performed using an 18-French rectal tube in place throughout the examination after initial placement by a technologist (n = 97) with mpMRI performed without rectal tube placement (n …