Robbin Newlin
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View article: High-throughput CRISPR-mediated 3D enrichment platform for functional interrogation of chemotherapeutic resistance
High-throughput CRISPR-mediated 3D enrichment platform for functional interrogation of chemotherapeutic resistance Open
Cancer is a disease of somatic mutations. These cellular mutations compete to dominate their microenvironment and dictate the disease outcome. While a therapeutic approach to target specific driver mutations helps to manage the disease, su…
View article: Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets
Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets Open
Recent advances in chemotherapeutics highlight the importance of molecularly-targeted perturbagens. Although these therapies typically address dysregulated cancer cell proteins, there are increasing therapeutic modalities that take into co…
View article: PAR2 regulates regeneration, transdifferentiation, and death
PAR2 regulates regeneration, transdifferentiation, and death Open