Rober Boshra
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View article: Decoding Analyses Show Dynamic Waxing and Waning of Event-Related Potentials in Coma Patients
Decoding Analyses Show Dynamic Waxing and Waning of Event-Related Potentials in Coma Patients Open
Background/Objectives: Coma prognosis is challenging, as patient presentation can be misleading or uninformative when using behavioral assessments only. Event-related potentials have been shown to provide valuable information about a patie…
View article: From Group-Level Statistics to Single-Subject Prediction: Machine Learning Detection of Concussion in Retired Athletes
From Group-Level Statistics to Single-Subject Prediction: Machine Learning Detection of Concussion in Retired Athletes Open
There has been increased effort to understand the neurophysiological effects of concussion aimed to move diagnosis and identification beyond current subjective behavioral assessments that suffer from poor sensitivity. Recent evidence sugge…
View article: From Group-Level Statistics to Single-Subject Prediction: Machine Learning Detection of Concussion in Retired Athletes
From Group-Level Statistics to Single-Subject Prediction: Machine Learning Detection of Concussion in Retired Athletes Open
There has been increased effort to understand the neurophysiological effects of concussion aimed to move diagnosis and identification beyond current subjective behavioral assessments that suffer from poor sensitivity. Recent evidence sugge…
View article: Tracking auditory mismatch negativity responses during full conscious state and coma
Tracking auditory mismatch negativity responses during full conscious state and coma Open
The mismatch negativity (MMN) is considered the electrophysiological change-detection response of the brain, and therefore a valuable clinical tool for monitoring functional changes associated with return to consciousness after severe brai…
View article: Years of play alter MRI measures of brain health in former Canadian Football League athletes: a pilot study
Years of play alter MRI measures of brain health in former Canadian Football League athletes: a pilot study Open
Introduction: Concussive and sub-concussive blows are commonly sustained during contact sports. Through a detailed neuroimaging analysis, this pilot study aimed to determine if a history of sport-related concussions exacerbated cognitive d…
View article: Case studies in neuroscience: reversible signatures of edema following electric and piezoelectric craniotomy drilling in macaques
Case studies in neuroscience: reversible signatures of edema following electric and piezoelectric craniotomy drilling in macaques Open
Close examination of structural MRI in eight nonhuman primates following craniotomy surgeries for intracranial electrophysiology highlights a prevalence of hyperintensities on T2-weighted scans following surgeries conducted using electric …
View article: Reversible edema following electric drilling of macaque craniotomy
Reversible edema following electric drilling of macaque craniotomy Open
In-vivo electrophysiology requires direct access to brain tissue, necessitating the development and refinement of surgical procedures and techniques that promote the health and well-being of the animal subjects. Here, we report a series of…
View article: Eliciting and Recording Event Related Potentials (ERPs) in Behaviourally Unresponsive Populations: A Retrospective Commentary on Critical Factors
Eliciting and Recording Event Related Potentials (ERPs) in Behaviourally Unresponsive Populations: A Retrospective Commentary on Critical Factors Open
A consistent limitation when designing event-related potential paradigms and interpreting results is a lack of consideration of the multivariate factors that affect their elicitation and detection in behaviorally unresponsive individuals. …
View article: Prevalence of spelling errors affects reading behavior across languages.
Prevalence of spelling errors affects reading behavior across languages. Open
This cross-linguistic study investigated the impact of spelling errors on reading behavior in five languages (Chinese, English, Finnish, Greek, and Hebrew). Learning theories predict that correct and incorrect spelling alternatives (e.g., …
View article: N2b Reflects the Cognitive Changes in Executive Functioning After Concussion: A Scoping Review
N2b Reflects the Cognitive Changes in Executive Functioning After Concussion: A Scoping Review Open
Objectives: The N2b is an event-related potential (ERP) component thought to index higher-order executive function. While the impact of concussion on executive functioning is frequently discussed in the literature, limited research has bee…
View article: Neurophysiological markers of cognitive deficits and recovery in concussed adolescents
Neurophysiological markers of cognitive deficits and recovery in concussed adolescents Open
The present study sought to determine: 1) whether concussed adolescents exhibited deficits in neurocognitive functioning as reflected by neurophysiological alterations; 2) if neurophysiological alterations could be linked to supplementary …
View article: On the time-course of functional connectivity: theory of a dynamic progression of concussion effects
On the time-course of functional connectivity: theory of a dynamic progression of concussion effects Open
The current literature presents a discordant view of mild traumatic brain injury and its effects on the human brain. This dissonance has often been attributed to heterogeneities in study populations, aetiology, acuteness, experimental para…
View article: Neurophysiological Correlates of Concussion: Deep Learning for Clinical Assessment
Neurophysiological Correlates of Concussion: Deep Learning for Clinical Assessment Open
Concussion has been shown to leave the afflicted with significant cognitive and neurobehavioural deficits. The persistence of these deficits and their link to neurophysiological indices of cognition, as measured by event-related potentials…
View article: Development of a point of care system for automated coma prognosis: a prospective cohort study protocol
Development of a point of care system for automated coma prognosis: a prospective cohort study protocol Open
Introduction Coma is a deep state of unconsciousness that can be caused by a variety of clinical conditions. Traditional tests for coma outcome prediction are based mainly on a set of clinical observations. Recently, certain event-related …
View article: Stepping Beyond Behaviour: Explainable Machine Learning for Clinical Neurophysiological Assessment of Concussion Progression
Stepping Beyond Behaviour: Explainable Machine Learning for Clinical Neurophysiological Assessment of Concussion Progression Open
The present dissertation details a sequence of studies in mild traumatic brain injury, the progression of its effects on the human brain as recorded by event-related electroencephalography, and potential applications of machine learning al…
View article: Normal Brain Response to Propofol in Advance of Recovery from Unresponsive Wakefulness Syndrome
Normal Brain Response to Propofol in Advance of Recovery from Unresponsive Wakefulness Syndrome Open
Up to 40% of individuals with unresponsive wakefulness syndrome (UWS) actually might be conscious. Recent attempts to detect covert consciousness in behaviorally unresponsive patients via neurophysiological patterns are limited by the need…
View article: Automated Machine Learning Framework for EEG/ERP Analysis: Viable Improvement on Traditional Approaches?
Automated Machine Learning Framework for EEG/ERP Analysis: Viable Improvement on Traditional Approaches? Open
Event Related Potential (ERP) measures derived from the electroencephalogram (EEG) have been widely used in research on language, cognition, and pathology. The high dimensionality (time x channel x condition) of a typical EEG/ERP dataset m…