Robert A. Gaunt
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View article: Finite element model predicts micromotion-induced strain profiles that correlate with the functional performance of Utah arrays in humans and non-human primates
Finite element model predicts micromotion-induced strain profiles that correlate with the functional performance of Utah arrays in humans and non-human primates Open
Objective. Utah arrays are widely used in both humans and non-human primates (NHPs) for intracortical brain–computer interfaces, primarily for detecting electrical signals from cortical tissue to decode motor commands. Recently, these arra…
View article: SpIC3D imaging for spinal in situ contrast 3D visualization
SpIC3D imaging for spinal in situ contrast 3D visualization Open
High-definition visualization techniques are critical for understanding the neuroanatomy of the spinal cord, an essential structure for sensorimotor and autonomic functions, in both healthy and pathological conditions. Magnetic resonance i…
View article: Intracortical microstimulation in humans: a decade of safety and efficacy
Intracortical microstimulation in humans: a decade of safety and efficacy Open
Background Intracortical microstimulation (ICMS) of somatosensory cortex can restore a sense of touch to people with spinal cord injury (SCI). In this early-feasibility clinical trial, we evaluate the safety, efficacy, and longevity of ICM…
View article: Conveying tactile object characteristics through customized intracortical microstimulation of the human somatosensory cortex
Conveying tactile object characteristics through customized intracortical microstimulation of the human somatosensory cortex Open
Microstimulation of the somatosensory cortex can evoke tactile percepts in people with spinal cord injury, providing a means to restore touch. While location and intensity can be reliably conveyed, two issues that prevent creating more com…
View article: Finite element model predicts micromotion-induced strain profiles that correlate with the functional performance of Utah arrays in humans and non-human primates
Finite element model predicts micromotion-induced strain profiles that correlate with the functional performance of Utah arrays in humans and non-human primates Open
Objective Utah arrays are widely used in both humans and non-human primates (NHPs) for intracortical brain-computer interfaces (BCIs), primarily for detecting electrical signals from cortical tissue to decode motor commands. Recently, thes…
View article: Mechanism to translation: Neural prostheses for the lower urinary tract
Mechanism to translation: Neural prostheses for the lower urinary tract Open
View article: Techniques to mitigate lead migration for percutaneous trials of cervical spinal cord stimulation
Techniques to mitigate lead migration for percutaneous trials of cervical spinal cord stimulation Open
Introduction Epidural spinal cord stimulation (SCS) is a clinical neuromodulation technique that is commonly used to treat neuropathic pain, with patients typically undergoing a one-week percutaneous trial phase before permanent implantati…
View article: Biomimetic stimulation patterns drive natural artificial touch percepts using intracortical microstimulation in humans
Biomimetic stimulation patterns drive natural artificial touch percepts using intracortical microstimulation in humans Open
Objective. Intracortical microstimulation (ICMS) of human somatosensory cortex evokes tactile percepts that people describe as originating from their own body, but are not always described as feeling natural. It remains unclear whether sti…
View article: SpIC3D imaging: Spinal In-situ Contrast 3D imaging
SpIC3D imaging: Spinal In-situ Contrast 3D imaging Open
SUMMARY High-definition visualization techniques are critical for understanding the neuroanatomy of the spinal cord, an essential structure for sensorimotor and autonomic functions, in both healthy and pathological conditions. Magnetic res…
View article: A Generalist Intracortical Motor Decoder
A Generalist Intracortical Motor Decoder Open
Mapping the relationship between neural activity and motor behavior is a central aim of sensorimotor neuroscience and neurotechnology. While most progress to this end has relied on restricting complexity, the advent of foundation models in…
View article: New Applications of Neurotechnologies for Neurological Disorders
New Applications of Neurotechnologies for Neurological Disorders Open
View article: A Roadmap for Implanting Electrode Arrays to Evoke Tactile Sensations Through Intracortical Stimulation
A Roadmap for Implanting Electrode Arrays to Evoke Tactile Sensations Through Intracortical Stimulation Open
Intracortical microstimulation (ICMS) is a method for restoring sensation to people with paralysis as part of a bidirectional brain–computer interface (BCI) to restore upper limb function. Evoking tactile sensations of the hand through ICM…
View article: Intracortical microstimulation of human somatosensory cortex induces natural perceptual biases
Intracortical microstimulation of human somatosensory cortex induces natural perceptual biases Open
Time-order error, a psychophysical phenomenon in which the duration in between successive stimuli alters perception, has been studied for decades by neuroscientists and psychologists. To date, however, the locus of these effects is unknown…
View article: Few-shot Algorithms for Consistent Neural Decoding (FALCON) Benchmark
Few-shot Algorithms for Consistent Neural Decoding (FALCON) Benchmark Open
Intracortical brain-computer interfaces (iBCIs) can restore movement and communication abilities to individuals with paralysis by decoding their intended behavior from neural activity recorded with an implanted device. While this activity …
View article: Biomimetic stimulation patterns drive natural artificial touch percepts using intracortical microstimulation in humans
Biomimetic stimulation patterns drive natural artificial touch percepts using intracortical microstimulation in humans Open
Objective Intracortical microstimulation (ICMS) of human somatosensory cortex evokes tactile percepts that people describe as originating from their own body, but are not always described as feeling natural. It remains unclear whether stim…
View article: A novel CNN-based image segmentation pipeline for individualized feline spinal cord stimulation modeling
A novel CNN-based image segmentation pipeline for individualized feline spinal cord stimulation modeling Open
Objective . Spinal cord stimulation (SCS) is a well-established treatment for managing certain chronic pain conditions. More recently, it has also garnered attention as a means of modulating neural activity to restore lost autonomic or sen…
View article: TACTILE EDGES AND MOTION VIA PATTERNED MICROSTIMULATION OF THE HUMAN CORTEX
TACTILE EDGES AND MOTION VIA PATTERNED MICROSTIMULATION OF THE HUMAN CORTEX Open
Intracortical microstimulation (ICMS) of somatosensory cortex evokes tactile sensations whose location and properties can be systematically manipulated by varying the electrode and stimulation parameters 1–3 . This phenomenon can be used t…
View article: A roadmap for implanting microelectrode arrays to evoke tactile sensations through intracortical microstimulation
A roadmap for implanting microelectrode arrays to evoke tactile sensations through intracortical microstimulation Open
Intracortical microstimulation (ICMS) is a method for restoring sensation to people with paralysis as part of a bidirectional brain-computer interface to restore upper limb function. Evoking tactile sensations of the hand through ICMS requ…
View article: Intracortical microstimulation of human somatosensory cortex is sufficient to induce perceptual biases
Intracortical microstimulation of human somatosensory cortex is sufficient to induce perceptual biases Open
A bstract Time-order error, a psychophysical phenomenon in which the duration in between successive stimuli alters perception, has been studied for decades by neuroscientists and psychologists. To date, however, the locus of these effects …
View article: Conveying tactile object characteristics through customized intracortical microstimulation of the human somatosensory cortex
Conveying tactile object characteristics through customized intracortical microstimulation of the human somatosensory cortex Open
Microstimulation of the somatosensory cortex can evoke tactile percepts in people with spinal cord injury, providing a means to restore touch. While location and intensity can be reliably conveyed, two issues that prevent creating more com…
View article: Volitional control of movement interacts with proprioceptive feedback in motor cortex during brain-computer interface control in humans
Volitional control of movement interacts with proprioceptive feedback in motor cortex during brain-computer interface control in humans Open
Vision and proprioception regulate motor output during reaching. To study the effects of sensory input on motor control, brain computer interfaces (BCIs) offer particular advantages. As part of a long-term clinical BCI trial, we implanted …
View article: High-frequency amplitude-modulated sinusoidal stimulation induces desynchronized yet controllable neural firing
High-frequency amplitude-modulated sinusoidal stimulation induces desynchronized yet controllable neural firing Open
Regaining sensory feedback is pivotal for people living with limb amputation. Electrical stimulation of sensory fibers in peripheral nerves has been shown to restore focal percepts in the missing limb. However, conventional rectangular cur…
View article: Microstimulation of human somatosensory cortex evokes task-dependent, spatially patterned responses in motor cortex
Microstimulation of human somatosensory cortex evokes task-dependent, spatially patterned responses in motor cortex Open
View article: Neural Data Transformer 2: Multi-context Pretraining for Neural Spiking Activity
Neural Data Transformer 2: Multi-context Pretraining for Neural Spiking Activity Open
The neural population spiking activity recorded by intracortical brain-computer interfaces (iBCIs) contain rich structure. Current models of such spiking activity are largely prepared for individual experimental contexts, restricting data …
View article: Sensory restoration for improved motor control of prostheses
Sensory restoration for improved motor control of prostheses Open
View article: Tessellation of artificial touch via microstimulation of human somatosensory cortex
Tessellation of artificial touch via microstimulation of human somatosensory cortex Open
When we interact with objects, we rely on signals from the hand that convey information about the object and our interaction with it. A basic feature of these interactions, the locations of contacts between the hand and object, is often on…
View article: Biomimetic multi-channel microstimulation of somatosensory cortex conveys high resolution force feedback for bionic hands
Biomimetic multi-channel microstimulation of somatosensory cortex conveys high resolution force feedback for bionic hands Open
A bstract Manual interactions with objects are supported by tactile signals from the hand. This tactile feedback can be restored in brain-controlled bionic hands via intracortical microstimulation (ICMS) of somatosensory cortex (S1). In IC…
View article: Amputee, clinician, and regulator perspectives on current and prospective upper extremity prosthetic technologies
Amputee, clinician, and regulator perspectives on current and prospective upper extremity prosthetic technologies Open
Existing prosthetic technologies for people with upper limb amputation are being adopted at moderate rates. Once fitted for these devices, many upper limb amputees report not using them regularly or at all. The primary aim of this study wa…
View article: A systematic review of computational models for the design of spinal cord stimulation therapies: from neural circuits to patient‐specific simulations
A systematic review of computational models for the design of spinal cord stimulation therapies: from neural circuits to patient‐specific simulations Open
Seventy years ago, Hodgkin and Huxley published the first mathematical model to describe action potential generation, laying the foundation for modern computational neuroscience. Since then, the field has evolved enormously, with studies s…
View article: High-density spinal cord stimulation selectively activates lower urinary tract nerves
High-density spinal cord stimulation selectively activates lower urinary tract nerves Open
Objective. Epidural spinal cord stimulation (SCS) is a potential intervention to improve limb and autonomic functions, with lumbar stimulation improving locomotion and thoracic stimulation regulating blood pressure. Here, we asked whether …