Explanipedia

Supplementary Table S1 from Phase I Study to Assess the Combination of Afatinib with Trastuzumab in Patients with Advanced or Metastatic HER2-Positive Breast Cancer Open

Alistair Ring, Duncan Wheatley, Helen Hatcher, R. A. Laing, Ruth Plummer , et al. · 2023

Supplementary Table S1. Best overall response (RECIST version 1.1)

Supplementary Table S1 from Phase I Study to Assess the Combination of Afatinib with Trastuzumab in Patients with Advanced or Metastatic HER2-Positive Breast Cancer Open

Alistair Ring, Duncan Wheatley, Helen Hatcher, R. A. Laing, Ruth Plummer , et al. · 2023

Supplementary Table S1. Best overall response (RECIST version 1.1)

Data from Phase I Study to Assess the Combination of Afatinib with Trastuzumab in Patients with Advanced or Metastatic HER2-Positive Breast Cancer Open

Alistair Ring, Duncan Wheatley, Helen Hatcher, R. A. Laing, Ruth Plummer , et al. · 2023

Purpose: The HER2 mAb, trastuzumab, is a standard therapy for patients with HER2-positive breast cancer before acquired resistance. Afatinib, an irreversible, oral, small-molecule ErbB family blocker, shows clinical activity in tras…

Data from Phase I Study to Assess the Combination of Afatinib with Trastuzumab in Patients with Advanced or Metastatic HER2-Positive Breast Cancer Open

Alistair Ring, Duncan Wheatley, Helen Hatcher, R. A. Laing, Ruth Plummer , et al. · 2023

Purpose: The HER2 mAb, trastuzumab, is a standard therapy for patients with HER2-positive breast cancer before acquired resistance. Afatinib, an irreversible, oral, small-molecule ErbB family blocker, shows clinical activity in tras…

The Observational Capabilities of the Square Kilometer Array Open

Maria Grazia Labate, L. Stringhetti, Gerhard Swart, Shin’ichiro Asayama, R. A. Laing , et al. · 2023

VLBI20-30: a scientific roadmap for the next decade -- The future of the European VLBI Network Open

T. Venturi, Z. Paragi, M. Lindqvist, A. Bartkiewicz, R. Beswick , et al. · 2021

This white paper describes the science case for Very Long Baseline Interferometry (VLBI) and provides suggestions towards upgrade paths for the European VLBI Network (EVN). The EVN is a distributed long-baseline radio interferometric array…

A Wideband Polarization Study of Cygnus A with the JVLA. I: The Observations and Data Open

M. Lerato Sebokolodi, Rick Perley, J. A. Eilek, C. L. Carilli, O. Smirnov , et al. · 2020

We present results from deep, wideband, high spatial and spectral resolution observations of the nearby luminous radio galaxy Cygnus A with the Jansky Very Large Array. The high surface brightness of this source enables detailed polarimetr…

VLBI20-30: a scientific roadmap for the next decade -- The future of the European VLBI Network Open

T. Venturi, Z. Paragi, M. Lindqvist, A. Bartkiewicz, R. Beswick , et al. · 2020

This white paper describes the science case for Very Long Baseline Interferometry (VLBI) and provides suggestions towards upgrade paths for the European VLBI Network (EVN). The EVN is a distributed long-baseline radio interferometric array…

The Cocoon Shocks of Cygnus A: Pressures and Their Implications for the Jets and Lobes Open

Bradford Snios, P. E. J. Nulsen, M. W. Wise, Martijn de Vries, M. Birkinshaw , et al. · 2018

We use 2.0 Msec of Chandra observations to investigate the cocoon shocks of Cygnus A and some implications for its lobes and jet. Measured shock Mach numbers vary in the range 1.18–1.66 around the cocoon. We estimate a total outburst energ…

The X-ray ribs within the cocoon shock of Cygnus A Open

Ryan Duffy, D. M. Worrall, M. Birkinshaw, P. E. J. Nulsen, M. W. Wise , et al. · 2018

This article has been accepted for publication in Monthly Notices of the Royal Astronomical Society. ©: 2018 The Authors. Published by Oxford University Press on behalf of the Royal Astronomical Society. All rights reserved

BlackHoleCam: Fundamental physics of the galactic center Open

C. Goddi, H. Falcke, M. Krämer, Luciano Rezzolla, Christiaan D. Brinkerink , et al. · 2017

using radio telescopes (including the Atacama large millimeter array or ALMA).The BlackHoleCam project exploits the synergy between these three different techniques and contributes directly to them at different levels.These efforts will ev…

MP79-20 PATHOLOGICAL ANALYSIS OF PATIENTS UNDERGOING RADICAL PROSTATECTOMY WHO WERE POTENTIAL CANDIDATES FOR FOCAL THERAPY Open

Ricardo Soares, R. A. Laing, Ben Haagsma, Krishna Patil, Christopher Eden , et al. · 2016

This analysis evaluates the impact of intrinsic and extrinsic factors on fluciclovine (18F) PET-CT scan detection rate (DR) in a biochemical relapse (BR) cohort.Diagnostic performance compared to histology and clinical follow-up is reporte…

Studies of Relativistic Jets in Active Galactic Nuclei with SKA Open

I. Agudo, Markus Boettcher, H. Falcke, Markos Georganopoulos, G. Ghisellini , et al. · 2015

Relativistic jets in active galactic nuclei (AGN) are among the most powerful astrophysical objects discovered to date. Indeed, jetted AGN studies have been considered a prominent science case for SKA, and were included in several differen…

Kinematics and Dynamics of kiloparsec-scale Jets in Radio Galaxies with SKA Open

R. A. Laing · 2015

We explore the use of SKA to deduce the physical parameters of kiloparsec-scale jet flows in radio galaxies.Jets in Active Galactic Nuclei are relativistic where they are first formed, but their speeds and compositions change as they propa…

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