Robert Bjerknes
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View article: Associations Between Weight-Related Measurements and Pubertal Markers in Norwegian Girls: The Bergen Growth Study 2
Associations Between Weight-Related Measurements and Pubertal Markers in Norwegian Girls: The Bergen Growth Study 2 Open
Context Previous studies that have documented the association between puberty and overweight and obesity have typically used body mass index (BMI) as a measure of weight status, and menarche as outcome. Other markers of body weight or pube…
Exposure to Per- and Polyfluoroalkyl Substances and Timing of Puberty in Norwegian Boys: Data from the Bergen Growth Study 2 Open
Per- and polyfluoroalkyl substances (PFAS) are widespread environmental contaminants with endocrine-disruptive properties. Their impact on puberty in boys is unclear. In this cross-sectional study, we investigated the association between P…
Levels of per- and polyfluoroalkyl substances (PFAS) in Norwegian children stratified by age and sex - Data from the Bergen Growth Study 2 Open
PFAS exposure was widespread in the sample population of Norwegian children analyzed in this study. Approximately one out of five children had PFAS levels above safety limits, indicating a potential risk of negative health effects. The maj…
View article: Deep phenotyping of pubertal development in Norwegian children: the Bergen Growth Study 2
Deep phenotyping of pubertal development in Norwegian children: the Bergen Growth Study 2 Open
Ultrasound-based assessments of puberty provided novel references for breast developmental stages and enabled the measurement of testicular volume on a continuous scale. Endocrine z-scores allowed for an intuitive interpretation of changin…
View article: Reference Curves for Pediatric Endocrinology: Leveraging Biomarker Z-Scores for Clinical Classifications
Reference Curves for Pediatric Endocrinology: Leveraging Biomarker Z-Scores for Clinical Classifications Open
Context Hormone reference intervals in pediatric endocrinology are traditionally partitioned by age and lack the framework for benchmarking individual blood test results as normalized z-scores and plotting sequential measurements onto a ch…
Psychological health in preschool children with underweight, overweight or obesity: a regional cohort study Open
Objective To examine if underweight (UW), overweight (OW) or obesity (OB), or body mass index (BMI) expressed as its SD score (BMI SDS), were associated with psychological difficulties in preschool children. Design Regional cohort study. S…
Low BMI, but not high BMI, influences the timing of puberty in boys Open
Background Previous studies investigating the association between weight status and onset of puberty in boys have been equivocal. It is currently unclear to what extent weight class influences puberty onset and progression. Objectives To e…
View article: Hormone References for Ultrasound Breast Staging and Endocrine Profiling to Detect Female Onset of Puberty
Hormone References for Ultrasound Breast Staging and Endocrine Profiling to Detect Female Onset of Puberty Open
Context Application of ultrasound (US) to evaluate attainment and morphology of glandular tissue provides a new rationale for evaluating onset and progression of female puberty, but currently no hormone references complement this method. F…
References for Ultrasound Staging of Breast Maturation, Tanner Breast Staging, Pubic Hair, and Menarche in Norwegian Girls Open
Context Discriminating adipose and glandular tissue is challenging when clinically assessing breast development. Ultrasound facilitates staging of pubertal breast maturation (US B), but has not been systematically compared to Tanner breast…
Reference data for testicular volume measured with ultrasound and pubic hair in Norwegian boys are comparable with Northern European populations Open
Aim To estimate references for testicular volume measured with ultrasound and Tanner stages of pubic hair in Norwegian boys, and to compare the timing of puberty with data from similar populations. Methods Testicular volume was derived fro…
A family‐oriented intervention programme to curtail obesity from five years of age had no effect over no intervention Open
Aim To examine the effect of a family‐oriented multidisciplinary intervention programme to curtail weight increase in young children with obesity. Methods Children who weighed more than one kilogram above the 97th percentile for height at …
View article: Testicular Ultrasound to Stratify Hormone References in a Cross-Sectional Norwegian Study of Male Puberty
Testicular Ultrasound to Stratify Hormone References in a Cross-Sectional Norwegian Study of Male Puberty Open
Context Testicular growth represents the best clinical variable to evaluate male puberty, but current pediatric hormone references are based on chronological age and subjective assessments of discrete puberty development stages. Determinat…
Norwegian children and adolescents in blended families are at risk of larger one‐year BMI increments Open
Aim To study how sociodemographic factors and family structure associate with baseline BMI z‐scores (BMIz) and BMIz change in 767 Norwegian children aged 6‐15 years. Methods Baseline BMIz and 1‐year BMIz increments in children from the Ber…
Social and somatic determinants of underweight, overweight and obesity at 5 years of age: a Norwegian regional cohort study Open
Objective To identify associations between the weight groups underweight (UW), overweight (OW) and obesity (OB) at 5 years of age and exposures related to pregnancy, anthropometric measures at birth, sociodemographic factors, and family he…
BMI and BMI SDS in childhood: annual increments and conditional change Open
Background Early detection of abnormal weight gain in childhood may be important for preventive purposes. It is still debated which annual changes in BMI should warrant attention. Aim To analyse 1-year increments of Body Mass Index (BMI) a…