Robert Bonek
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View article: Occupational burnout and perceived barriers at work in Polish neurologists
Occupational burnout and perceived barriers at work in Polish neurologists Open
Burnout is highly prevalent among Polish neurologists, driven by both individual vulnerabilities (belonging to a younger age group, depression, insomnia) and organizational stressors (workload, administrative burden). Strengthening profess…
View article: OPERA and ORATORIO – how the world has been changed by “music”
OPERA and ORATORIO – how the world has been changed by “music” Open
Multiple sclerosis is a chronic autoimmune disease that progresses over time, leading to disability. The condition is still incurable, but available therapies are increasingly effective. Ocrelizumab is the first anti-CD20 monoclonal antibo…
View article: Amantadine in unvaccinated patients with early, mild to moderate <scp>COVID</scp>‐19: A randomized, placebo‐controlled, double‐blind trial
Amantadine in unvaccinated patients with early, mild to moderate <span>COVID</span>‐19: A randomized, placebo‐controlled, double‐blind trial Open
Background and purpose Adamantanes were listed as an interesting option as an early intervention against COVID‐19. We aimed to evaluate the effectiveness of amantadine in preventing the progression of COVID‐19 and its neurological sequelae…
View article: Late and very late onset neuromyelitis optica spectrum disorders – a case series
Late and very late onset neuromyelitis optica spectrum disorders – a case series Open
Background and purpose: Neuromyelitis optica spectrum disorders are a group of autoimmune diseases leading to severe visual and motor impairment with a median disease onset at 39 years. Materials and methods: We present a case series of fo…
View article: Predictive Value of the Third Ventricle Width for Neurological Status in Multiple Sclerosis
Predictive Value of the Third Ventricle Width for Neurological Status in Multiple Sclerosis Open
The third ventricle width (3VW) is an easily calculated measure of brain atrophy. The aim of this study was to evaluate the relation of 3VW to cognitive impairment with adjustment for demographic and clinical confounders, including depress…
View article: Efficacy and Safety of Masitinib in Progressive Forms of Multiple Sclerosis
Efficacy and Safety of Masitinib in Progressive Forms of Multiple Sclerosis Open
This study provides Class II evidence that masitinib 4.5 mg/kg/d decreased progression of disability, measured by the EDSS, in adults with PPMS or patients with nSPMS (with no exacerbations in the last 2 years).
View article: Predictive Value of the Third Ventricle Width for Neurological Status in Multiple Sclerosis
Predictive Value of the Third Ventricle Width for Neurological Status in Multiple Sclerosis Open
The third ventricle width (3VW) is an easily calculated measure of brain atrophy. The aim of this study was to evaluate the relation of 3VW to cognitive impairment with adjustment for demographic and clinical confounders, including depress…
View article: JC Virus Seroprevalence and JCVAb Index in Polish Multiple Sclerosis Patients Treated with Immunomodulating or Immunosuppressive Therapies
JC Virus Seroprevalence and JCVAb Index in Polish Multiple Sclerosis Patients Treated with Immunomodulating or Immunosuppressive Therapies Open
The use of a highly-effective treatment for multiple sclerosis (MS) is associated with a severe risk of developing complications, such as progressive multifocal leukoencephalopathy (PML) caused by the John Cunningham virus (JCV). The aim o…
View article: The Impact of Motor Disability and the Level of Fatigue on Adherence to Therapeutic Recommendations in Patients with Multiple Sclerosis Treated with Immunomodulation
The Impact of Motor Disability and the Level of Fatigue on Adherence to Therapeutic Recommendations in Patients with Multiple Sclerosis Treated with Immunomodulation Open
Aim: The aim of the study was to clarify whether the motor disability and the fatigue-related syndrome affect the level of compliance with therapeutic recommendations. Methods: Prospective studies were conducted among 165 patients treated …
View article: Neurochemical Changes in the Brain and Neuropsychiatric Symptoms in Clinically Isolated Syndrome
Neurochemical Changes in the Brain and Neuropsychiatric Symptoms in Clinically Isolated Syndrome Open
To assess cognitive impairment and affective symptoms and their association with damage to normal-appearing white matter (NAWM) in patients with clinically isolated syndrome (CIS), we compared neuropsychological test scores between patient…
View article: JC Virus Seroprevalence and JCVAb Index in Polish Multiple Sclerosis Treatment-Naïve Patients
JC Virus Seroprevalence and JCVAb Index in Polish Multiple Sclerosis Treatment-Naïve Patients Open
Multiple sclerosis (MS) treatment with new agents is associated with the risk of the development of progressive multifocal leukoencephalopathy (PML). The seropositivity and a high index of anti-John Cunningham virus (JCV) antibodies are so…
View article: Recommendations of the Polish Medical Society of Radiology and the Polish Society of Neurology for a protocol concerning routinely used magnetic resonance imaging in patients with multiple sclerosis
Recommendations of the Polish Medical Society of Radiology and the Polish Society of Neurology for a protocol concerning routinely used magnetic resonance imaging in patients with multiple sclerosis Open
Magnetic resonance imaging (MRI) is a widely used method for the diagnosis of multiple sclerosis that is essential for the detection and follow-up of the disease. OBJECTIVE: The Polish Medical Society of Radiology (PLTR) and the Polish Soc…
View article: Neurochemical Changes in Brain and Neuropsychiatric Symptoms in Clinically Isolated Syndrome
Neurochemical Changes in Brain and Neuropsychiatric Symptoms in Clinically Isolated Syndrome Open
To assess cognitive impairment and affective symptoms and their association with damage to normal-appearing white matter (NAWM) in patients with clinically isolated syndrome (CIS), we compared neuropsychological test scores between patient…
View article: Polish validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS battery): correlation of cognitive impairment with mood disorders and fatigue
Polish validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS battery): correlation of cognitive impairment with mood disorders and fatigue Open
The Polish version of BICAMS is a valid and reliable tool for the assessment of cognitive impairment in patients with MS.
View article: An international multicenter efficacy and safety study of <scp>IqYmune</scp> in initial and maintenance treatment of patients with chronic inflammatory demyelinating polyradiculoneuropathy: <scp>PRISM</scp> study
An international multicenter efficacy and safety study of <span>IqYmune</span> in initial and maintenance treatment of patients with chronic inflammatory demyelinating polyradiculoneuropathy: <span>PRISM</span> study Open
This prospective, multicenter, single‐arm, open‐label phase 3 study aimed to evaluate the efficacy and safety of IqYmune in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Patients received one induction dos…
View article: Adherence to Therapeutic Recommendations in Patients Suffering from Multiple Sclerosis
Adherence to Therapeutic Recommendations in Patients Suffering from Multiple Sclerosis Open
Introduction. Multiple sclerosis is a chronic, inflammatory, immune demyelinating disease of the central nervous system. The effectiveness of MS treatment depends primarily on the effectiveness of drugs and the patient’s compliance with th…
View article: Recommendations of the Polish Medical Society of Radiology andthe Polish Society of Neurology for a protocol concerning routinely usedmagnetic resonance imaging in patients with multiple sclerosis
Recommendations of the Polish Medical Society of Radiology andthe Polish Society of Neurology for a protocol concerning routinely usedmagnetic resonance imaging in patients with multiple sclerosis Open
Magnetic resonance imaging (MRI) is a widely used method for the diagnosis of multiple sclerosis (MS) that is essential for the detection and follow-up of the disease. The Polish Medical Society of Radiology (PLTR) and the Polish Society o…